This is, unsurprisingly, completely wrong. Last year, there were between 28 and 37 trans people murdered in the US, under varying circumstances (advocates do not discuss the motives, because the goal to build a narrative about a nonexistent hate crime epidemic and clearly establishing that even a handful of these deaths were not hate crimes undermines that). The total population of trans people is estimated at about 1.3 million, so the murder rate for trans people is 3 in 100,000, which is the same as the murder rate for white people, the archetypal super safe and unthreatened demographic.
Black trans women have a 10 in 100,000 rate*, which while a bit less than double the rate of 6 in 100,000 rate for black women, is still a quarter of the staggering 40 in 100,000 for men, so they're still very safe (and in shitposting terms, given they're all men, they're actually extremely safe compared to other black men).
"But Miles," come the objection from some hypothicical Rick supporter, "he said 'murdered for existing', not just murdered in general, so perhaps he meant that black trans women face an unusually high rate of hate crime victimization!"
If we decided to be insanely generous to Rick here and interpret it in that light, he's still wrong, this time on two counts. There's no data on the killer's motives for these cases, and even groups like the HRC that go out of their way to frame things in a narrative supporting light and pushing many contradicting details as out of the way as possible**, only a tiny handful of cases established why they were killed, and it's rarely out of explict bias. One was just an unlucky bystander in an unrelated shooting. So not only is that not proven, it's the exact opposite of a statistical fact.
*It also bares mentioning that with populations this small, it's extremely easy to play with numbers and get a higher results. If 2 professional MTG players get murdered out of a pool of like a thousand pro MTG players, that's a 200 in 100,000 murder rate, but no sane human being would argue that there's therefore an epidemic of anti-MTG hate crimes.
**last time I looked into this, loads of the victims were hookers, a famously dangerous profession, this time there's no mention of that for most victims, but rather than explaining they were not hookers, there's a suspicious non specificity in regards to what exactly they did for a living. You can probably connect the dots yourself