Wuhan Coronavirus: Megathread - Got too big

[Nique la mere de Macron]

I can't wait for their surprised Pikachu faces.

It would be a shame if Antifa and/or BLM decided that this would be a good time to have an old-fashioned riot.

 

[Meriasek]

That doesn't even seem possible. Did literally everyone quit over the mandates?

Maybe they're otherwise sick. Here I noticed a lot of people getting sick with regular colds this year, and often very, very sick, too. But Straya is on the other hemisphere and shouldn't have that issue now.
Maybe it's just because of the normal, regular, and totally well known phenomenon of young people dying of heart attacks. Dunno why they don't prepare for that, I mean, it has been well known that it happens very often.

/edit:
I really hope they're gonna make vaccines mandatory here soon. Because people will drag that shit to the courts, and they will have to look at all the numbers in detail, and will realize that shit's off.
...
Well, that's what I would hope in non-clown-world. Realistically, it'll go to court and all the corrupt faggots will just proclaim shit to be totally fine

 

[Gorilla Tessellator]

@borsabil @Lichen Bark

I think it's possible that COVID-19 could actually be beaten with little more than promptly administering Pepcid and Benadryl. It's not just suppression of mast cell activation. They're antioxidant and possibly antiviral, too.

Effects of diphenhydramine and famotidine on lipid peroxidation and activities of antioxidant enzymes in different rat tissues - PubMed

The potential antioxidant activity of diphenhydramine (histamine H1-receptor antagonist) and famotidine (histamine H2 receptor antagonist) was studied. Diphenhydramine inhibited the spontaneous, Fe(II)-induced and Fe(II)/ascorbate-induced lipid peroxidation, while famotidine showed a biphasic...

pubmed.ncbi.nlm.nih.gov

Identification of antiviral antihistamines for COVID-19 repurposing

There is an urgent need to identify therapies that prevent SARS-CoV-2 infection and improve the outcome of COVID-19 patients. Although repurposed drugs with favorable safety profiles could have significant benefit, widely available prevention or treatment ...

www.ncbi.nlm.nih.gov

Lethal COVID-19 (when it occurs) is almost certainly a result of iron-induced lipid peroxidation.

The role of iron in the pathogenesis of COVID-19 and possible treatment with lactoferrin and other iron chelators

Iron overload is increasingly implicated as a contributor to the pathogenesis of COVID-19. Indeed, several of the manifestations of COVID-19, such as …

www.sciencedirect.com

In the protocol I got from the doctor who prescribed me Ivermectin, Pepcid was mentioned, fortunately it's easy to get.
What you linked suggests that of utmost importance is the fatty acid composition. If one ingests too much PUFA this lipid perioxidation would be sky-high. That's probably another reason why fat people suffer more. Unfortunately, the change of diet would not help immediately, as it takes some time for the body to replace PUFA, but it makes me feel even stronger about avoiding PUFA in my diet.

I wanted to ask you a question about arginine. I take L-Lysine daily to suppress viral replication, and I found at least one paper about potential of L-Lysine for COVID (my folder with all the papers is a total mess, so forgive me I will not link it in this post). You want to keep ratio of lysine/arginine high so it will suppress herpes zoster. I saw that outbreaks of herpes zoster are more common both post-vaccine and in some COVID-19 patients. Wouldn't then arginine be counterproductive?

 

[Super-Chevy454]

It would be a shame if Antifa and/or BLM decided that this would be a good time to have an old-fashioned riot.

They decided to riot anyway against anti-vaxxers. https://kiwifarms.net/threads/break...i-vaccine-mandate-protestors-in-boston.105021

 

[Drain Todger]

In the protocol I got from the doctor who prescribed me Ivermectin, Pepcid was mentioned, fortunately it's easy to get.
What you linked suggests that of utmost importance is the fatty acid composition. If one ingests too much PUFA this lipid perioxidation would be sky-high. That's probably another reason why fat people suffer more. Unfortunately, the change of diet would not help immediately, as it takes some time for the body to replace PUFA, but it makes me feel even stronger about avoiding PUFA in my diet.

Yep, exactly. All the fats and DNA start oxidizing, especially PUFAs, but also cardolipin, LDL, et cetera, due to the Fenton reaction. The end-result is ferroptosis from iron and H2O2 forming lipid hydroperoxides, and parthanatos from Ca2+ dependent pathways overactivating PARP-1.

The oxidized lipids promote autoantibody formation. As I've said before, this is very similar to some aspects of systemic lupus erythematosus.

Immune cell activation in severe COVID-19 resembles lupus

In severe cases of COVID-19, an exuberant activation of antibody-producing cells resembles that seen in systemic lupus erythematosus (SLE).

news.emory.edu

Oxidation-Specific Epitopes in Non-Alcoholic Fatty Liver Disease

An improper balance between the production and elimination of intracellular reactive oxygen species causes increased oxidative stress. Consequently, DNA, RNA, proteins, and lipids are irreversibly damaged, leading to molecular modifications that disrupt normal function. In particular, the...

www.frontiersin.org

I wanted to ask you a question about arginine. I take L-Lysine daily to suppress viral replication, and I found at least one paper about potential of L-Lysine for COVID (my folder with all the papers is a total mess, so forgive me I will not link it in this post). You want to keep ratio of lysine/arginine high so it will suppress herpes zoster. I saw that outbreaks of herpes zoster are more common both post-vaccine and in some COVID-19 patients. Wouldn't then arginine be counterproductive?

The safest way to raise NO without having to take arginine is via the enterosalivary nitrate pathway (like drinking beet juice, for instance). If there is excess superoxide, this nitric oxide will form peroxynitrite, however; peroxynitrite damages DNA and injures mitrochondria, promoting cell stress/death, and also destroys the BH4 cofactor needed by endothelial NOS to make nitric oxide, causing it to make more superoxide instead. Therefore, the superoxide must be removed by superoxide dismutase enzymes, which produce hydrogen peroxide.

This H2O2 contributes to the Fenton reaction unless it, in turn, is broken down into water by catalase or glutathione peroxidase. This is why NAC and selenium are vital; GPX uses both glutathione and selenium as redox substrates to make H2O2 into water. Curcumin in turmeric helps activate Nrf2, raising antioxidant enzyme levels.

This is, of course, why people who are dying of COVID-19 have low vitamin D, low selenium, low glutathione, et cetera. Vitamin D pumps calcium back out of cells, preventing NADPH oxidase overactivation, reducing superoxide release, and also preventing mitochondrial/ER stress and inhibiting coronavirus replication (coronaviruses need lots of calcium pulled into cells as part of their life cycle). Glutathione and selenium help detoxify ROS.

Surviving COVID-19 sepsis is basically all about raising antioxidant capacity by any means.

 

[Escaped Abortion]

The safest way to raise NO without having to take arginine is via the enterosalivary nitrate pathway (like drinking beet juice, for instance). If there is excess superoxide, this nitric oxide will form peroxynitrite, however; peroxynitrite damages DNA and injures mitrochondria, promoting cell stress/death, and also destroys the BH4 cofactor needed by endothelial NOS to make nitric oxide, causing it to make more superoxide instead. Therefore, the superoxide must be removed by superoxide dismutase enzymes, which produce hydrogen peroxide.

This H2O2 contributes to the Fenton reaction unless it, in turn, is broken down into water by catalase or glutathione peroxidase. This is why NAC and selenium are vital; GPX uses both glutathione and selenium as redox substrates to make H2O2 into water. Curcumin in turmeric helps activate Nrf2, raising antioxidant enzyme levels.

This is, of course, why people who are dying of COVID-19 have low vitamin D, low selenium, low glutathione, et cetera. Vitamin D pumps calcium back out of cells, preventing NADPH oxidase overactivation, reducing superoxide release, and also preventing mitochondrial/ER stress and inhibiting coronavirus replication (coronaviruses need lots of calcium pulled into cells as part of their life cycle). Glutathione and selenium help detoxify ROS.

Surviving COVID-19 sepsis is basically all about raising antioxidant capacity by any means.

Hmm, so to my daily routine of 5000-10000 iu D, 600mg quercetin, 600mg NAC, 500mg Tumeric, 25 mg zinc, 500 mg C, is there anything I should add or remove? I haven't ever tried beet juice, but I could look into it to fight against these consequences?

Also, PUFAs are poly unsaturated fats? I mostly cook with butter, but there are times where I use vegetable oil because a recipe specifically requests it, or for shallow frying.

 

[Drain Todger]

Hmm, so to my daily routine of 5000-10000 iu D, 600mg quercetin, 600mg NAC, 500mg Tumeric, 25 mg zinc, 500 mg C, is there anything I should add or remove? I haven't ever tried beet juice, but I could look into it to fight against these consequences?

Also, PUFAs are poly unsaturated fats? I mostly cook with butter, but there are times where I use vegetable oil because a recipe specifically requests it, or for shallow frying.

Definitely selenium and beets, possibly even lactoferrin. Avoid PUFAs and dietary iron.

Ferroptosis: mechanisms and links with diseases - Signal Transduction and Targeted Therapy

Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis, autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by the accumulation of lethal lipid species derived from the peroxidation of lipids, which can be prevented by iron...

www.nature.com

Here's a neat little experiment: Google just about anything recommended as a COVID-19 therapeutic, and "antioxidant". Fluvoxamine, melatonin, budesonide, famotidine, diphenhydramine, and most of these other drugs recommended for COVID-19 all have off-target antioxidant effects that may be the "real" therapeutic mode of action.

 

[borsabil]

Regeneron's COVID antibody drug shows protection for up to 8 months

Regeneron Pharmaceuticals Inc said on Monday a single dose of its antibody cocktail reduced the risk of contracting COVID-19 by 81.6% in a late-stage trial, in the two to eight months period following the drug's administration.

www.reuters.com

Regeneron Pharmaceuticals Inc (REGN.O) said on Monday a single dose of its antibody cocktail reduced the risk of contracting COVID-19 by 81.6% in the two to eight months period following the drug's administration in a late-stage trial.

The results showed that antibody therapy, REGEN-COV, has the potential to provide long-lasting immunity from COVID-19 infection, said Myron Cohen, who leads monoclonal antibody efforts for the U.S. National Institutes of Health-sponsored COVID Prevention Network.


Such immunity is particularly important for immunocompromised people and those not responding to vaccines, the company said.

So an antibody therapy is more efficacious in reducing transmission and disease than any of the vaccines. Oh and no adverse risk profile to worry about.

The vaccines aren't vaccines. They're incredibly shitty antibody therapies with horrendous side effects that are being used as short term preventatives. Calling them vaccines was for marketing purposes and to allow the government to mandate their use.

With new and safer treatments available that are patented, so will allow big pharma to continue to fleece the public, hopefully governments will see sense and shit can them all.

Over 5 months with Covid being eliminated in one of the few places on the planet that relies on horse dewormer to treat the coof.

 

[fhqwhgads]

Hmm, so to my daily routine of 5000-10000 iu D, 600mg quercetin, 600mg NAC, 500mg Tumeric, 25 mg zinc, 500 mg C, is there anything I should add or remove? I haven't ever tried beet juice, but I could look into it to fight against these consequences?

Also, PUFAs are poly unsaturated fats? I mostly cook with butter, but there are times where I use vegetable oil because a recipe specifically requests it, or for shallow frying.

Regarding turmeric, I'd read this page on curcumin: https://examine.com/supplements/curcumin/

You might be better off with a curcumin extract than using turmeric, but turmeric itself can be fine as long as you pair it with something that increases its absorption such as piperine.

 

[Nique la mere de Macron]

I am legit baffled at the "no employees/staff" situation, mostly because it doesn't seem confined to places that have been giving out extremely generous unemployment benefits or extending eviction moratoriums or extending benefits that otherwise would have expired by now. So I don't think that "well, you're not paying enough/it pays better or almost as good to just be on the dole" is the real issue.

Spoiler: No sympathy expected

I have been trying to hire a part-time (15h/week) employee for something like NINE MONTHS now. The hours are regular and not weird (no evenings or weekends or graveyard nonsense). Pay is over market. Days off are granted no questions asked. There are Christmas and birthday bonuses. Raises every six months. No vaccination requirement. A "do whatever you're comfortable with" policy on masks. And I can't get anybody to even come in for an INTERVIEW. Have been relying on a temp agency, but it is far from an optimal solution because it's more expensive for me, the employees aren't getting nearly what they would get if they were just working direct, and of course the contract with the agency prevents me from hiring one of the people they send, a few of whom have been pretty good.

It also seems like the issue is not really confined to jobs/industries that tend to hire/attract people in a particular age group, which sends the theory that this is COVID driven out the window, although of course you can't say the same thing for the possibility that it's vaccination side-effects driven.

WTF is up with this????

 

[Meriasek]

One of the most annoying things here is the infationary use of "solidarity". "The anti-vaxxers are denying solidarity", "Why should they expect solidarity if they won't give any solidarity by getting vaxxed?"
Fucking "solidarity this, solidarity that". I'm sick of this shit. Thanks to these people I'm an egotist now.

 

[Puff]

One of the most annoying things here is the infationary use of "solidarity". "The anti-vaxxers are denying solidarity", "Why should they expect solidarity if they won't give any solidarity by getting vaxxed?"
Fucking "solidarity this, solidarity that". I'm sick of this shit. Thanks to these people I'm an egotist now.

HA. I already was an objectivist.

 

[borsabil]

I am legit baffled at the "no employees/staff" situation, mostly because it doesn't seem confined to places that have been giving out extremely generous unemployment benefits or extending eviction moratoriums or extending benefits that otherwise would have expired by now. So I don't think that "well, you're not paying enough/it pays better or almost as good to just be on the dole" is the real issue.

Spoiler: No sympathy expected

I have been trying to hire a part-time (15h/week) employee for something like NINE MONTHS now. The hours are regular and not weird (no evenings or weekends or graveyard nonsense). Pay is over market. Days off are granted no questions asked. There are Christmas and birthday bonuses. Raises every six months. No vaccination requirement. A "do whatever you're comfortable with" policy on masks. And I can't get anybody to even come in for an INTERVIEW. Have been relying on a temp agency, but it is far from an optimal solution because it's more expensive for me, the employees aren't getting nearly what they would get if they were just working direct, and of course the contract with the agency prevents me from hiring one of the people they send, a few of whom have been pretty good.

It also seems like the issue is not really confined to jobs/industries that tend to hire/attract people in a particular age group, which sends the theory that this is COVID driven out the window, although of course you can't say the same thing for the possibility that it's vaccination side-effects driven.

WTF is up with this????

The US, on average, adds around 2 million people per year to it's worker pool. A combination of natural growth in the native population and immigration.

Note that labor force participation is static but the gross number (total employed/unemployed) is only slightly increasing, a substantial number of people seem to have just vanished.

https://www.bls.gov/news.release/pdf/empsit.pdf

The first column is October 2020 the last October 2021. These are gross unadjusted numbers from the household survey.

The civilian labor force has grown by just under 1 million, way below the historical average. In comparison the annualised increase for 2018 was 2.5 million.

Where have all these people gone?

There are only a few ways for adults not to be included in the count. Go to prison, go to a nursing home (become institutionalised), leave the country for good or die.

I can tell you for sure that this phenomena is not limited to the US. There are massive labor shortages everywhere. Even in parts of my country, that have never suffered a Covid outbreak, are reporting sudden and unexpected dislocations in the labor market.

Is it the vaccines? I don't know. I doubt a million or so people dying could be covered up so more likely it's a combination of a lot of factors. But it's unprecedented and the fact almost no one is discussing it is definitely strange.

 

[Gorilla Tessellator]

Definitely selenium and beets, possibly even lactoferrin. Avoid PUFAs and dietary iron.

Ferroptosis: mechanisms and links with diseases - Signal Transduction and Targeted Therapy

Ferroptosis is an iron-dependent cell death, which is different from apoptosis, necrosis, autophagy, and other forms of cell death. The process of ferroptotic cell death is defined by the accumulation of lethal lipid species derived from the peroxidation of lipids, which can be prevented by iron...

www.nature.com

Here's a neat little experiment: Google just about anything recommended as a COVID-19 therapeutic, and "antioxidant". Fluvoxamine, melatonin, budesonide, famotidine, diphenhydramine, and most of these other drugs recommended for COVID-19 all have off-target antioxidant effects that may be the "real" therapeutic mode of action.

What do you think about replacing diphenhydramine with cyproheptadine? Personally, I think Benadryl is nasty, and cypro is nicer.

 

[Honka Honka Burning Love]

But someone forgot to tell Big Bird these mRNA vaccines against corona-chan are still experimental.

Man this means that if I kill big bird and fry him up I can't claim it is non GMO food

 

[Salubrious]

I want to know where the NBA got this "2 months for the J&J vaccine", because I'm sure they must have consulted somebody on it. I don't think the NBA pulled it out of thin air.

 

[Gorilla Tessellator]

I want to know where the NBA got this "2 months for the J&J vaccine", because I'm sure they must have consulted somebody on it. I don't think the NBA pulled it out of thin air.

View attachment 2699293

So it begins...

 

[ddw]

11th of June, Cuxhaven, Germany: Healthy kids without pre-existing conditions are not getting the vaccine.
5th of November, Cuxhaven, Germany: Since a kid died to the vaccine, now only healthy kids without pre-existing conditions are getting the vaccine.

Yeah, I don't even know. I don't know how we can ever go back from this madness. How can we look people in the eyes ever again, knowing what's underneath their masks? How can one live in a society knowing that these people are your neighbours and colleagues?
This is fucking depressing.

again, pretty much everyone i knew who bought into this were people i actively wanted to stay away from beforehand

 

[The golden neckbeard]

View attachment 2699076

The US, on average, adds around 2 million people per year to it's worker pool. A combination of natural growth in the native population and immigration.

Note that labor force participation is static but the gross number (total employed/unemployed) is only slightly increasing, a substantial number of people seem to have just vanished.

https://www.bls.gov/news.release/pdf/empsit.pdf

View attachment 2699155


The first column is October 2020 the last October 2021. These are gross unadjusted numbers from the household survey.

The civilian labor force has grown by just under 1 million, way below the historical average. In comparison the annualised increase for 2018 was 2.5 million.

Where have all these people gone?

There are only a few ways for adults not to be included in the count. Go to prison, go to a nursing home (become institutionalised), leave the country for good or die.

I can tell you for sure that this phenomena is not limited to the US. There are massive labor shortages everywhere. Even in parts of my country, that have never suffered a Covid outbreak, are reporting sudden and unexpected dislocations in the labor market.

Is it the vaccines? I don't know. I doubt a million or so people dying could be covered up so more likely it's a combination of a lot of factors. But it's unprecedented and the fact almost no one is discussing it is definitely strange.

Karl denninger over at ticker forum said it started with vaccinations months ago

Its also accelerating...i think there is a bigger story here. These were young people

Unemployment benefits have been gone for awhile now.

Would you notice one out of 350 missing? I wouldnt. Young people do die sometimes.

Was it coof? My money is on vaccines just killing people and it being written off as other things and "short illnesses"

CDC is stupid. They cant even sort a spread sheet of lot numbers to see which batches have poor quality

They are killing people and dont even know it or do know it and someone has been gagged because admitting the vaccine has killed a million people would cause a full on revolt.

The problem is growing so its not something that they will be able to hide. Labor shortages will continue

 

[Mrs. Addams]

That doesn't even seem possible. Did literally everyone quit over the mandates?

I am legit baffled at the "no employees/staff" situation, mostly because it doesn't seem confined to places that have been giving out extremely generous unemployment benefits or extending eviction moratoriums or extending benefits that otherwise would have expired by now. So I don't think that "well, you're not paying enough/it pays better or almost as good to just be on the dole" is the real issue.

Spoiler: No sympathy expected

I have been trying to hire a part-time (15h/week) employee for something like NINE MONTHS now. The hours are regular and not weird (no evenings or weekends or graveyard nonsense). Pay is over market. Days off are granted no questions asked. There are Christmas and birthday bonuses. Raises every six months. No vaccination requirement. A "do whatever you're comfortable with" policy on masks. And I can't get anybody to even come in for an INTERVIEW. Have been relying on a temp agency, but it is far from an optimal solution because it's more expensive for me, the employees aren't getting nearly what they would get if they were just working direct, and of course the contract with the agency prevents me from hiring one of the people they send, a few of whom have been pretty good.

It also seems like the issue is not really confined to jobs/industries that tend to hire/attract people in a particular age group, which sends the theory that this is COVID driven out the window, although of course you can't say the same thing for the possibility that it's vaccination side-effects driven.

WTF is up with this????

From what I’ve been hearing around town, the nurses all transitioned to non-hospital related jobs due to burnout.

As far as the non-nursing jobs, there’s a steady stream of people begging for work but they want upper level jobs, with specific qualifications, not part time or entry level work. Have companies truncated those sort of positions to save costs?

I’ve also heard the following theories:
- All the people who would have filled those jobs died of Covid
- People relocated to cheeper parts of the country and moved back in with their parents (so maybe they’re not working right now?)
- Who is watching the kids that are constantly out of school after Covid exposure? Have moms left the workforce to do this?
- A bunch of the last 10 years worth of male college grads are NEETS and aren’t getting jobs
- Are the boomers retiring?