This is why YouTubers are hyping Tales Of The Valiant as "the real 6e". I wasn't around for 4e, but I imagine the rise of Pathfinder was like this?
For what it's worth, I gave TotV a skim and I'm not really seeing any real differences. Not enough to pick it up anyway. There's a video going over the differences, and it's kind of needed because to a casual reader, it's basically the same game.
There are other 5e derivatives out there that seem to be doing more with the system. I already mentioned Nimble 5e.
I've said before that I've used Eberron as a backdoor pulp adventure setting. What's a good setting for other genres? And what are some good desert settings? These can be DnD or other systems.
There's obvious stuff. Darksun, Ravenloft, and I've used Eberron as a backdoor pulp adventure before. What about spies, or a desert adventures? I know of Al Quidim, but there's not much content for it, and Pathfinder's equiverlent has been ruined by canon events getting rid of the major villains.