Wuhan Coronavirus: Megathread - Got too big

[Super-Chevy454]

I'm pretty sure I heard about Vitamin D back in May and it was considered another conservative conspiracy theory, but I'm too lazy to prove that.

There was that article published last December then I mentionned in an earlier post about Vitamin D.

Pandemic Penitents | City Journal

Lockdowns are more about faith than science.

www.city-journal.org

https://archive.vn/ybNhg

This specific strategy is no longer in favor among public health officials, but the spirit of the Flagellants lives on. Instead of beatdowns, today’s regulators favor lockdowns, which are less bloody but inflict more social pain. For all the talk about following science, the authorities—and much of the citizenry—can’t resist the primal intuition that a pandemic can be quelled only through public penance. Consider two strategies for dealing with the Covid-19 virus: urge the public to spend time outside in the sun to build up their vitamin D, and to take supplements of the vitamin, repeatedly demonstrated to protect against viral infection; or shut down most businesses, deprive children of classroom education, and order everyone to stay home, a strategy never previously tested and yet to prove effective.
Which strategy would you try first? If you chose the vitamin D, you have no future in the public-health establishment. While a few researchers are touting the vitamin’s potential and advocating government programs to distribute the supplements during the pandemic, the Centers for Disease Control can’t bring itself even to suggest that people take the pills on their own. In its Covid-19 guidelines, the CDC declares that “there are insufficient data to recommend either for or against the use of vitamin D.”
Somehow, though, the “insufficient data” problem disappeared when it came to lockdowns and mask mandates. Before the pandemic, the official expert consensus was against those measures, but the consensus was promptly discarded in the hope that these sacrifices might help. The evidence since then could easily be called insufficient, given the lack of randomized studies and the inconvenient data showing that places with lockdowns didn’t fare any better than the places without strict measures. And given what has emerged about the minuscule rate of transmission in outdoor settings, you could certainly say there’s insufficient evidence to order people to stay inside their homes or to mandate masks outdoors.

 

[Salubrious]

There was that article published last December then I mentionned in an earlier post about Vitamin D.

Pandemic Penitents | City Journal

Lockdowns are more about faith than science.

www.city-journal.org

https://archive.vn/ybNhg

No no, I meant this.

TL;DR = This is an article from June 2nd warning against Vitamin D "misinformation".

https://www.healio.com/news/endocrinology/20200602/researchers-caution-against-misinformation-on-vitamin-d-during-covid19-pandemic

Edit: Here's May 19th.

So yeah, they were calling Vitamin D misinformation two months in.

https://www.nutraingredients.com/Article/2020/05/22/COVID-19-Internet-rife-with-misinformation-about-Vitamin-D-say-scientists#

 

[Andre Richardson]

Oh how the tables have turned.....

 

[Salubrious]

Oh how the tables have turned.....

I think the only thing that bothers me is that New Yorkers have been saying this shit for MONTHS and got ignored.

In fact, there was of course a "fact check" by Politifact and it was "Mostly False" that Cuomo even killed the 6000 that he was originally accused of.

This was AUGUST. We've known this shit for at least six months already.

https://www.politifact.com/factchecks/2020/aug/24/michael-caputo/hhs-official-blames-cuomo-nursing-home-covid-death/

 

[teriyakiburns]

I think the only thing that bothers me is that New Yorkers have been saying this shit for MONTHS and got ignored.

In fact, there was of course a "fact check" by Politifact and it was "Mostly False" that Cuomo even killed the 6000 that he was originally accused of.

This was AUGUST. We've known this shit for at least six months already.

https://www.politifact.com/factchecks/2020/aug/24/michael-caputo/hhs-official-blames-cuomo-nursing-home-covid-death/

Cuomo's problem is that he was getting too much mindshare and could have presented a threat to President BidenHarris in 2024. His usefulness to the party has ended, so he has to be taken out before that happens.

 

[Drain Todger]

It's downright criminal that the WHO, CDC, and other public health organizations and their spokesmen didn't recommend this from the start. Imagine if Dr. Fauci said on his 60 Minutes interview a year ago that "if you can't wear a mask, take vitamin D, and even if you wear a mask, take vitamin D." Thousands of people would still be alive and no doubt millions more would've had easier times when they caught the Chinese virus. If an autistic lunatic like @Drain Todger knows it based on his OCD reading of medical papers, why weren't global health agencies reporting this? And vitamin D is good for lots of other shit too. I started taking vitamin D supplements because I figured that if I caught the Shanghai Shakes then I'd want as easy time as possible and it made me feel better than I have in years.

COVID-19 is not what people think it is. It really isn't. If people listen to the way the media has presented this virus, they are told that it's a respiratory disease, that it's a pneumonia. While it's accurate to say that it causes a form of pneumonia and acute lung injury, what SARS-CoV-2 actually does is insidious. It attacks the lining of people's blood vessels and causes them to become edematous and leak into the lungs and other vital organs. People who die of COVID-19 do not die of pneumonia. They die of sepsis, heart failure, and disseminated intravascular coagulation brought on by vicious coagulopathy. This is why COVID-19 seems like an "everything-virus" that can injure every organ. It's because the blood vessels supply blood to every organ, and a virus that injures the blood vessels injures the organs, too.

But that's not all it does. COVID-19 also triggers hypoxemia by attacking the lungs, starving the brain and other vital organs of oxygen. It also triggers severe inflammation in each organ that it touches. And, on top of all of that, it causes extreme oxidative stress that leads to lipid peroxidation, ferroptosis, and injury to the mitochondria and reduction in their ability to generate energy for cells.

SARS-CoV-2 pulls a very strange sleight-of-hand with its host-virus interactions. Its proteins disable the body's own antioxidant enzymes, directly activate inflammatory pathways, destroy ACE2 receptors needed to inactivate bradykinin, and also act as calcium ion channels.

What groups of people are most strongly affected by COVID-19? Fat people and black people. What groups of people have metabolic syndrome and a reduced ability to deal with oxidative stress in their vascular endothelium? Fat people and black people. Let me explain.

As I've said before, inside our blood vessels is an enzyme called nitric oxide synthase that makes nitric oxide. Nitric oxide is a tiny signaling molecule that has many uses in the body, because it rapidly diffuses through normally impermeable cell membranes. Nitric oxide is also found in various other places, like cigarette smoke. Notice how smokers are less likely to develop severe COVID-19?

Nitric oxide is actually antiviral against SARS-CoV. It prevents the palmitoylation of the Spike protein of SARS-CoV, and research dating back years has shown this. Palmitoylation is the attachment of a fatty acid to a protein. In the case of SARS-CoV-2 and its spike, this makes it more infectious and makes it replicate faster.

Why does SARS-CoV-2 induce oxidative stress in the host by triggering intracellular calcium release and a bradykinin storm? Simple. It wants to destroy the nitric oxide in your body so it can replicate faster. Here's how that happens. When you have oxidative stress in your body, you have a lot of a free radical called superoxide floating around. This is the O2 anion referred to with the notation O2-. It's just O2, but it's missing an electron. It wants to strip that electron off of surrounding substances, like fats (like your cell membranes, cholesterol, whatever) in order to replace it. Free radicals are molecules that are "unhappy" because they're missing an electron, and this makes them prone to react to things around them in a process very similar to rust, or fire. Free radicals "rust" things in your body. That's what people mean when they say having an "antioxidant diet can help you live longer". What they're actually saying is you should eat things that act as sacrificial molecules to donate electrons to these free radicals so they don't strip electrons off of your cells, your DNA, whatever. Anyway, oxidation-reduction reactions in the body are vital for just about everything, including, uhh, breathing, so you can't live without them. But, I digress.

When superoxide comes in contact with nitric oxide, it forms peroxynitrite by an irreversible chemical reaction that destroys both the superoxide and the nitric oxide. Peroxynitrite is not antiviral against SARS-CoV-2's spike. What it does do is contribute to nitrosative stress.

Superoxide also has other downstream radicals, like hydrogen peroxide, hypochlorous acid, et cetera, and neutrophils dump out enzymes that make tons of these to try and destroy infections. If you have enough hypochlorous acid circulating around, it will actually destroy free heme and injure macrophages and promote the release of iron into the bloodstream. Unliganded free iron is highly reactive (just like it is outside the body, where it rusts readily), and when it reacts with hydrogen peroxide and superoxide, it makes hydroxyl radicals that are so reactive, they oxidize your lipid membranes within nanoseconds, causing irreversible damage.

This is why severe COVID-19 patients have the hallmarks of ferroptosis, or iron-mediated cell death caused by oxidative stress.

SARS-CoV-2 infection: can ferroptosis be a potential treatment target for multiple organ involvement? - Cell Death Discovery

Since the outbreak of the new coronavirus in 2019 (SARS-CoV-2), many studies have been performed to better understand the basic mechanisms and clinical features of the disease. However, uncertainties of the underlying mechanisms of multiple organ involvement remain. A substantial proportion of...

www.nature.com

It's why they have antiphospholipid antibodies (something you usually see in fucking lupus), which form as a reaction to oxidatively damaged phospholipids.

More than 50% of patients with COVID-19 positive for antiphospholipid antibodies

A significant proportion of patients with COVID-19 — up to 52% by one metric — are at least transiently positive for potentially pathogenic antiphospholipid autoantibodies, according to a speaker at ACR Convergence.“Do COVID-19 patients get blood clots? Yes, they do,” Yu Zuo, MD, a physician...

www.healio.com

What does Vitamin D do? It regulates intracellular calcium levels and reduces superoxide production by regulating NADPH oxidase. It also activates a bunch of beneficial genetic activity through its receptor. This, in turn, means less superoxide. Which, in turn, means less nitric oxide destroyed by reaction with superoxide to form peroxynitrite, which means more nitric oxide in the blood vessels, which means slower replication of the virus due to the nitric oxide preventing the palmitoylation of the Spike.

African-Americans, as a group, have far less nitric oxide production in their blood vessels than other ethnic groups. This is a proven scientific fact. It's why they're more susceptible to metabolic syndrome (hypertension, diabetes, etc.). It's also very likely why COVID-19 is so much more aggressive in their bodies than in other groups.

https://www.ahajournals.org/doi/10.1161/01.CIR.0000129087.81352.7A?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed&

There are a number of ways to tackle this problem therapeutically, actually, on top of Vitamin D. Apocynin (it's found in Kutki Powder), quercetin, resveratrol, dietary nitrate, N-acetylcysteine, glutathione supplementation, et cetera. So long as you can prevent the positive feedback loop of inflammation and oxidative stress in COVID-19, you can probably keep someone out of the ICU.

It's insane they would shut people indoors, close gyms, and essentially encourage obesity for a disease that is worse in the obese and people lacking vitamin D. But nothing about this makes any sense. Always remember that according to the media's own studies, something like 90% of all COVID-19 coverage in the media is pessimistic compared to around 60% in medical journals. And in those percentages, remember that the media ALWAYS emphasizes shit like "oh this new strain is even more deadly" compared to things like "here's how vitamin D can reduce deaths".

I'll tell you how it makes sense. It makes sense if the motherfuckers out there who are intentionally perpetuating this crisis are sick, anti-natalist Illuminati bastards who are using a manufactured crisis to usher in the New World Order.

My only intentions in all of this, all along, were to see if I could find out what the hell COVID-19 was, why it caused the symptoms that it did, and what could be done to treat it. Back in March/April, I thought they were going to lock things down for, at the most, a month, to see if they could arrest transmission completely and prevent the virus from becoming endemic. But they didn't. They allowed it to become endemic, while also locking people down for months and months and months, to the point that their health and their livelihoods were jeopardized.

I have never seen such incompetence in my life. In fact, active malice is a far more reasonable explanation for the policies that public officials have pursued. Stuffing COVID-19 positive people into nursing homes in New York was not an innocent little mistake. It was murder. Andrew Cuomo has blood on his hands.

 

[Super-Chevy454]

I think the only thing that bothers me is that New Yorkers have been saying this shit for MONTHS and got ignored.

In fact, there was of course a "fact check" by Politifact and it was "Mostly False" that Cuomo even killed the 6000 that he was originally accused of.

This was AUGUST. We've known this shit for at least six months already.

https://www.politifact.com/factchecks/2020/aug/24/michael-caputo/hhs-official-blames-cuomo-nursing-home-covid-death/

Just in case if Politifact delete that article.

PolitiFact - Is Cuomo directive to blame for nursing home COVID deaths as HHS official claims?

PolitiFact is a fact-checking website that rates the accuracy of claims by elected officials and others on its Truth-O-Meter.

web.archive.org

https://archive.vn/laggK

 

[Zbk3VmLfujjzjxBd43tL]

Cuomo's problem is that he was getting too much mindshare and could have presented a threat to President BidenHarris in 2024. His usefulness to the party has ended, so he has to be taken out before that happens.

It's fascinating seeing a political purge in action where all the garbage Cuomo did that should've seen forced to resign 10 months ago is now brought to the forefront so to remove a political opponent.

African-Americans, as a group, have far less nitric oxide production in their blood vessels than other ethnic groups. This is a proven scientific fact. It's why they're more susceptible to metabolic syndrome (hypertension, diabetes, etc.). It's also very likely why COVID-19 is so much more aggressive in their bodies than in other groups.

I'm skeptical of this as much as I am how people were saying how Asian lungs were different than other race's lungs and that's why the Chinese were doing so bad. Culture and poverty is to blame for a lot of African American health problems with the exception of vitamin D (which wouldn't be an issue for all African Americans, just some, given that dark skinned peoples like native South Africans or Tasmanian Aboriginals lived very far south for centuries with no ill health).

I have never seen such incompetence in my life. In fact, active malice is a far more reasonable explanation for the policies that public officials have pursued. Stuffing COVID-19 positive people into nursing homes in New York was not an innocent little mistake. It was murder. Andrew Cuomo has blood on his hands.

See Hanlon's razor "never attribute to malice what can be explained by stupidity." I think we're seeing a mix of both, since it's incredible how stupid and spineless politicians are.

 

[Bosmadden]

I think the only thing that bothers me is that New Yorkers have been saying this shit for MONTHS and got ignored.

In fact, there was of course a "fact check" by Politifact and it was "Mostly False" that Cuomo even killed the 6000 that he was originally accused of.

This was AUGUST. We've known this shit for at least six months already.

https://www.politifact.com/factchecks/2020/aug/24/michael-caputo/hhs-official-blames-cuomo-nursing-home-covid-death/

We knew about the policies to admit Covid patients into nursing homes back in April. It was being discussed in the right wing press and blogosphere and dismissed as a conspiracy theory. Shit me and other people were discussing it on this thread.

This is Dr. Rachel Levine, Biden's new Dep Sec of Health

Dr. Levine is Jewish troon.

He was previously the Health Sec for the state of Pennsylvania.

Here's an article in the American Spectator from May 2020

Note what is alleged: On March 29, Pennsylvania joined New York and other northeastern states in “ordering nursing homes to admit medically stable residents infected with the coronavirus,” despite warnings from groups like the American Health Care Association that such “health directives” could “unnecessarily cost more lives.”

Pennsylvanians who gasped when they heard that Andrew Cuomo had permitted such directives in New York recoiled in angered amazement when they heard it might have happened in their state, as well.

They were likewise aghast to hear that Dr. Levine removed her own 95-year-old mother from a nursing home. “My mother requested and my sister and I, as her children, complied to move her to another location during the COVID-19 outbreak,” Levine confirmed in a press conference.

Let's all remember that the supposed justification for the lockdowns is to protect the frail and elderly, particularly nursing home patients.

When faced with the first wave the same people pushing this narrative decided to discharge Covid positive patients out of their hospitals and into nursing homes, knowing full well thousands of people would die as a result.

It's not just New York a whole bunch of blue states ran the same policies and is the main reason the first wave of Covid was so deadly.

Cuomo's problem is that he was getting too much mindshare and could have presented a threat to President BidenHarris in 2024. His usefulness to the party has ended, so he has to be taken out before that happens.

Cuomo's done. This story is growing legs and it's a big tell that the DNC media is now covering this.

All of the politicians and government officials who ran this policy should be charged with mass murder.

 

[Bakarina]

Stay in your pod until we flatten the curve and ease burdens on hospitals you get all 30 vaccines, fucking Nazi bigot! Why do you want grandma Little Jimmy to DIE?!?!?!? (archive)

View attachment 1924750

It sounds like stress got to him more than the virus. Stress can kill and can lead to a variety of health problems including weakening the immune system.

 

[Honka Honka Burning Love]

Cuomo's problem is that he was getting too much mindshare

There is also the fact that he is fucking awful.

 

[FatalTater]

Yesterday I went out in the American midwest to do some shopping. Unfortunately I went with my paranoid mask nazi friend. First thing he said to me was about how the CDC wants people to wear 2 masks. I asked if the stores here were asking for that and I got a pouty "No, grumble grumble our governor sux blah blah mumble" as a response. Neither of us wore 2 masks. Neither did anyone else as far as I saw.
We went to Walmart, Aldi, and Dollar Tree. I wore a mask in the stores and the parking lot because it was cold, but took it off in the car. My friend even wore his inside the car except for when we had lunch.
On the way back home he mentioned that he even wears his mask outside in his yard because he's afraid that someone two blocks away might breathe a germ and it will drift over to him. I said that I saw a study that showed that it doesn't do that. He said he saw a study that said it did. I asked him how to know which thing to believe. He said that he's going to believe the worst thing, because his life is the definition of Murphy's Law. (He's not entirely wrong there)
Oddly enough he doesn't fear germs enough to not come around me and my household, or the polyamorous couple he plays cards with once a week.
I wonder if Covid misinformation leading to mental illness will be studied in the future.

Take your vitamin D, guys. Just 1000 IU a day can help, especially in winter.

 

[Bosmadden]

It's fascinating seeing a political purge in action where all the garbage Cuomo did that should've seen forced to resign 10 months ago is now brought to the forefront so to remove a political opponent.

I'm skeptical of this as much as I am how people were saying how Asian lungs were different than other race's lungs and that's why the Chinese were doing so bad. Culture and poverty is to blame for a lot of African American health problems with the exception of vitamin D (which wouldn't be an issue for all African Americans, just some, given that dark skinned peoples like native South Africans or Tasmanian Aboriginals lived very far south for centuries with no ill health).

See Hanlon's razor "never attribute to malice what can be explained by stupidity." I think we're seeing a mix of both, since it's incredible how stupid and spineless politicians are.

It's the opposite. Darker skinned people absorb less sunlight than the lighter skinned, they would tend to be more prone to Vit D deficiency in colder climates.

The current thinking is that white people only became white around 10,000 years ago. Not as a response to living in colder climates but due to darker skin becoming a mal-adaption with the discovery of farming.

In hunter gatherer societies Vitamin D deficiency is a non issue as red meat is high in Vitamin D. When people became dependent on grains for their calorie intake the only way for their bodies to maintain sufficient vitamin D was via the sun, hence we evolved white folk.

 

[Honka Honka Burning Love]

I wonder if Covid misinformation leading to mental illness will be studied in the future.

The kids between 6-13 that are growing up and still learning social cues and the like are 100% going to have mental issues later on.

 

[The handsome tard]

I think the only thing that bothers me is that New Yorkers have been saying this shit for MONTHS and got ignored.

In fact, there was of course a "fact check" by Politifact and it was "Mostly False" that Cuomo even killed the 6000 that he was originally accused of.

This was AUGUST. We've known this shit for at least six months already.

https://www.politifact.com/factchecks/2020/aug/24/michael-caputo/hhs-official-blames-cuomo-nursing-home-covid-death/

Its a trend about this pandemic with the media claiming shit that the so called "conspiracy theorists/science deniers" have been saying for several months and acting like they are the ones that just found about it.

 

[Salubrious]

Its a trend about this pandemic with the media claiming shit that the so called "conspiracy theorists/science deniers" have been saying for several months and acting like they are the ones that just found about it.

I feel like I'm more of a "conspiracy theorist" now than I was 12 months ago because a shocking number of these theories turns out to be right.

 

[mandatorylurk]

For those keeping track, Trump's adminisatration was hitting this goal for a month, then it dropped under Biden to below 800,000/day, the point Biden said we'll just have to deal with the virus because there's nothing we can do. And on top of all this they've lied and said they inherited no plan which is so bad even cuck Fauci had to call them on the lie.

 

[Just wandering]

Stay in your pod until we flatten the curve and ease burdens on hospitals you get all 30 vaccines, fucking Nazi bigot! Why do you want grandma Little Jimmy to DIE?!?!?!? (archive)

View attachment 1924750

I dunno if it linked, but locking kid inside, always wearing mask and always cleaning their and with purell would atrophy their immune system? Also when authority were originally against mask they said it was bacterial and fungal nest and people didn't know how to use, they maybe were right. Looking at how people don't really use it properly and don't even clean them...

 

[Salubrious]

View attachment 1924978

For those keeping track, Trump's adminisatration was hitting this goal for a month, then it dropped under Biden to below 800,000/day, the point Biden said we'll just have to deal with the virus because there's nothing we can do. And on top of all this they've lied and said they inherited no plan which is so bad even cuck Fauci had to call them on the lie.

To be fair (because I am a fair man), the number of people that are vaccinated was naturally going to drop off over time as the most paranoid and the "mandatory workers" all got their shots early on and then it tapers from there.

But yes, as far as Biden being a liar, and pretending like Trump had no plan, and all Biden's other lies, that's dead on. In fact, restrictions in some places seem to be getting worse as "new variants" keep getting magically found every time it looks like there's some light as the end of the tunnel.

 

[NyQuilninja]

It's fascinating seeing a political purge in action where all the garbage Cuomo did that should've seen forced to resign 10 months ago is now brought to the forefront so to remove a political opponent.

I'm skeptical of this as much as I am how people were saying how Asian lungs were different than other race's lungs and that's why the Chinese were doing so bad. Culture and poverty is to blame for a lot of African American health problems with the exception of vitamin D (which wouldn't be an issue for all African Americans, just some, given that dark skinned peoples like native South Africans or Tasmanian Aboriginals lived very far south for centuries with no ill health).

See Hanlon's razor "never attribute to malice what can be explained by stupidity." I think we're seeing a mix of both, since it's incredible how stupid and spineless politicians are.

Or it was Clever and calculated way to rid themselves of the elderly draining the system