I don't know what happened. He first married a nice Japanese waifu. I guess he fucked that up because then he was with that stripper and decided(?) to wife her and knock her up, and I'm not clear in which order.
To try and give a quick and dirty of the fucked up love life of Trey Parker:
Trey Parker was a simp madly in love with his high school sweetheart (who was mormon so in case you wonder where Trey's mormon fetish shit came from). His sweetheart? Not so fucking loyal or even god-damn bright. She was cheating on him with a member of a local college chorus group and WEEKS before South Park debuted on TV, Trey caught her mid-fuck with the chorus guy and dumped her on the spot.
Finding out that his "one true love" was a whore had a radicalizing effect of Trey, turning him full-on misogynist towards women. It also bled into South Park itself: Cartman's mom (named after Trey's ex) because a degenerate whore on the show, while Wendy because the sort of "idealized" version of his ex from before Trey catching her fucking another man.
Trey was now super rich and along with Matt, were big into wasting their newfound fortune on whores and drugs and stripper-prostitutes. But Trey was way more into it than Matt, in that he went out of his way to form himself a harem of stripper-whores, preying on women who he fed the line that he was a newly made millionaire that was betrayed by his childhood sweetheart and could never love again... unless he met the right woman who could teach him to love again.
A couple of weeks of love bombing and finding out if the strippers he gaslit were also hookers on the side, and Trey would hire them for the night and then proceed to bring them into hotel rooms filled with Trey, Matt, and their horny friends and coworkers and fuck the poor stripper whore's brains out. Or she'd come in, find several other whores in the room, and be asked on the spot if she would let the other prostitutes "break her in" to the world of Sapphic sex while he jerked off and gave orders about all of the stuff he wanted done to her sexually by the other hookers, as far as ways Trey dropped his wounded nice guy act and used hookers to vent his hatred towards women over his ex's betrayal.
His second wife was a semi-famous stripper/hooker on the Colorado strip club scene and after several years of degrading sex shit, became Trey's bottom bitch who helped him organize/run his harem for him. Trey paid his harem well for their service, but word leaked out and Trey got put on the "problematic client watch list" on nearly every major strip club in Colorado, getting to the point that newbie strippers weren't allowed to service Trey for fear he'd start gaslighting them and inviting them to a "no means yes, yes means roleplaying lesbian prison rape" meet ups.
Eventually Trey got cold feet over his whoring and boozing and decided to settle down, with a wealthy Japanese heiress and try and have a normal vanilla life as a millionaire. But he couldn't give up his drugs and freaky sex and his bottom bitch and started cheating on his Japanese wife with his bottom bitch. They divorced and since the wife was wealthy, Trey dodged a bullet on the alimony front and resumed his whoring and boozing degeneracy with his future second wife. Who he eventually married after his accountant gave him the proverbial come to Jesus speech about how it was reaching a point financially, that Trey marrying a whore and potentially paying alimony to her, would be cheaper in the long term than paying her thousands of dollars every week for hook ups.
at this point i wouldn't be surprised if matt and trey give up and turn south park into a straight up fujoshit show
They teased doing that but stopped when they found that it wasn't driving away viewers like they thought it would.
Hence them tripling down on Randy and his pot farm last season, since they've realized fans HATE Randy and the pot farm.