Wuhan Coronavirus: Megathread - Got too big

[KEKMUHLORD]

That's funny. That reminds me of what YoungRippa says: he will only take the vaccine if it unlocks the X gene.

The Based Libertarian himself! I love that dude. I got to watch more of his stuff.

 

[ConfederateIrishman]

Ma'am, this is a wendy's drive thru, can I take your order?

Uhhh can I have a Jr. Baconator with a side of Nuggets and an Diet Coke? Thanks

 

[The High Prophet of Truth]

https://twitter.com/disclosetv/status/1382370017031950341

 

[Ruin]

View attachment 2087299

https://twitter.com/disclosetv/status/1382370017031950341

What a fucking shock. I got called a Nazi for saying this almost a year ago.

 

[Hollywood Hitler]

It's always interesting to see the dynamic New York City vs. "Upstate New York" (aka everything NOT NYC). A lot of people in the city resent the people upstate and vice versa. Even a lot of big politicians like our two Senators consider anything not NYC to be beneath them, and that's half of the population.

Put it this way. Biden won NYS easily (of course), but of his 2 million margin of victory, 1.6 million came from NYC (1.8 million if you include Westchester). So upstate NY is still blue, but it's only like 54% blue.


That's funny. That reminds me of what YoungRippa says: he will only take the vaccine if it unlocks the X gene.

I consider Westchester not upstate since it's a stones throw away from NYC, and how people from Westchester have the same yuppie liberal mentality as those who live in NYC.

 

[Salubrious]

I consider Westchester not upstate since it's a stones throw away from NYC, and how people from Westchester have the same yuppie liberal mentality as those who live in NYC.

I did too, but I didn't want to get (well acksually) since it's not one of the five boroughs.

I'm actually more surprised that Staten Island voted for Trump, pretty heavily too (57-42), but then I saw that it was 75% white (the only borough with a non-Hisplanic white majority) and only 12% below poverty and that explained it.

 

[FAQnews Correspondent]

What a fucking shock. I got called a Nazi for saying this almost a year ago.

You'll still get called a nazi, even if you show video proof.

 

[Salubrious]

View attachment 2087299

https://twitter.com/disclosetv/status/1382370017031950341

Archiving it before the Twitter ban.

youtube-dl.exe -f best https://twitter.com/disclosetv/status/1382370017031950341 -o "CNN Biased with COVID 2021-04-14.mp4"

 

[Sekirodiealot]

I wonder how much overhaul will emergency power go through once the world come back to it's senses

 

[Salubrious]

I wonder how much overhaul will emergency power go through once the world come back to it's senses

If anything, I expect blue states to say that they didn't have enough power because too many people complained or "spread misinformation."

 

[bippu_as_fuck_ls400]

I wonder how much overhaul will emergency power go through once the world come back to it's senses

Lawmakers seek long-term limit on governors’ emergency power​

https://apnews.com/article/legislat...-legislature-113b9847aab2df17975d59da92ebf07c (https://archive.ph/mwlwh)
Excerpt:

As governors loosen long-lasting coronavirus restrictions, state lawmakers across the U.S. are taking actions to significantly limit the power they could wield in future emergencies.

The legislative measures are aimed not simply at undoing mask mandates and capacity limits that have been common during the pandemic. Many proposals seek to fundamentally shift power away from governors and toward lawmakers the next time there is a virus outbreak, terrorist attack or natural disaster.

 

[The High Prophet of Truth]

 

[FAQnews Correspondent]

View attachment 2087554

I, uhh, don't think that was a vaccine dude.

 

[Escaped Abortion]

It's like that euphoria you see people at megachurches experience. They worked themselves into a religious fervor and this is the release. They feel their god within them.

 

[knobslobbin]

Burning man announced they will require proof of vaccine and a negative test for burning man (if it happens) this year.

Have companies gone insane? All medical info, including vaccination status, is protected private info. You can't discriminate based on that info, much less even ask for it. Please lord let the lawsuits rape all these retarded virtue signalling cunts into bankruptcy quickly and repeatedly.

https://journal.burningman.org/2021/04/news/official-announcements/april-2021-update/

edit: imagine if an event required proof of HIV- status to enter. The left would go insane. They have no principles anymore, they are completely morally bankrupt and hopefully enough people will abandon their evil soon because of how blatant they are with the mindless hate now.

 

[4AMPudding]

4) If some variant will actually cause ADE in vaccinated , governments will flip their shit, crank restrictions to 11 and start welding people inside their homes.

What does ADE stand for/mean in this context?

 

[Vecr]

What does ADE stand for/mean in this context?

Antibody dependent enhancement. It probably won't happen, a least to a large degree, because the T cell response is strong.

 

[Drain Todger]

No, I feel you. I'm having a hard time dealing with this myself and I've been feeling like I'm not able to take much more of it either.

I don't intend to get vaccinated, and I'm worried about my folks getting their booster shot on Tuesday. I'm scared things will never go back to some semblance of normalcy.

I want to try and focus on the things that I still have. Focus on the good things that do occasionally pop up and I want to remind myself that this won't last forever. At some point, something will have to give and we all just need to hold on. I can only hope we each don't lose too much along the way.

Stay strong friend.

I'm very, very concerned about the safety and efficacy of the vaccine for a number of reasons. I've found evidence that the Spike protein of SARS-CoV-2 can cause a great deal of inflammation on its own, by attacking the vascular endothelium at various points, increasing the permeability of the BBB, and by binding to bacterial lipopolysaccharides.

The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier

As researchers across the globe have focused their attention on understanding SARS-CoV-2, the picture that is emerging is that of a virus that has ser…

www.sciencedirect.com

SARS-CoV-2 spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity

Abstract. There is a link between high lipopolysaccharide (LPS) levels in the blood and the metabolic syndrome, and metabolic syndrome predisposes patients to s

academic.oup.com

This would happen if someone is infected with the virus, but it would also happen if their cells were made to manufacture this protein by an mRNA vaccine. Loose Spike proteins can do this even without the rest of the virus.

Other issues include the possible lack of protection from variants:

https://www.jewishpress.com/news/health-and-medicine/coronavirus/study-south-african-variant-can-break-through-pfizers-covid-19-vaccine/2021/04/10/

Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2 mRNA vaccinated individuals

The SARS-CoV-2 pandemic has been raging for over a year, creating global detrimental impact. The BNT162b2 mRNA vaccine has demonstrated high protection levels, yet apprehension exists that several variants of concerns (VOCs) can surmount the immune defenses generated by the vaccines...

www.medrxiv.org

As well as the possibility of ADE:

https://www.chop.edu/centers-programs/vaccine-education-center/vaccine-safety/antibody-dependent-enhancement-and-vaccines

Antibody-dependent enhancement and SARS-CoV-2 vaccines and therapies - Nature Microbiology

Mechanisms of antibody-dependent enhancement of disease and mitigation strategies for SARS-CoV-2 vaccines and therapies are discussed.

www.nature.com

What does ADE stand for/mean in this context?

Antibody-Dependent Enhancement of disease, like Dengue Fever, West Nile Virus, or HIV.

The whole point of a vaccine is to train the body's adaptive immune system to produce antibodies that will lock onto the proteins of a virus, neutralizing it and allowing it to be drawn into macrophages, phagocytized, broken down, etc.

ADE happens when you get infected with one strain of a virus (or vaccinated against that strain), and then get infected with a different strain. Memory B lymphocytes react to the second strain, but produce antibodies against the first strain. There's an actual term for this. It's called original antigenic sin:

Original antigenic sin - Wikipedia

en.wikipedia.org

These antibodies only partially neutralize the virion. So, what happens is that the antibody locks onto the Fc receptor of a macrophage and draws the whole virion into the cell, and then the virion starts infecting the macrophage and reproducing in it. Basically, the antibodies start helping the virus infect cells that they would never have been able to enter before (for instance, SARS-CoV-2's Spike has an affinity for ACE2, Neuropilin-1, and so forth, but it can't infect Fc receptors on macrophages without help).

If SARS-CoV-2 has ADE, and people start vaccinating themselves against one strain only to be infected by another, they could be very badly fucked by the second strain. This has a historical precedent. Dengvaxia failed in the Philippines for the same exact reason.

Antibody-Dependent Enhancement: A Challenge for Developing a Safe Dengue Vaccine

In 2019, the United States Food and Drug Administration accorded restricted approval to Sanofi Pasteur's Dengvaxia, a live attenuated vaccine (LAV) for dengue fever, a mosquito-borne viral disease, caused by four antigenically distinct dengue virus serotypes (DENV 1-4). The reason for this...

www.frontiersin.org

In 2019, the United States Food and Drug Administration accorded restricted approval to Sanofi Pasteur's Dengvaxia, a live attenuated vaccine (LAV) for dengue fever, a mosquito-borne viral disease, caused by four antigenically distinct dengue virus serotypes (DENV 1-4). The reason for this limited approval is the concern that this vaccine sensitized some of the dengue-naïve recipients to severe dengue fever. Recent knowledge about the nature of the immune response elicited by DENV viruses suggests that all LAVs have inherent capacity to predominantly elicit antibodies (Abs) against the pre-membrane (prM) and fusion loop epitope (FLE) of DENV. These antibodies are generally cross-reactive among DENV serotypes carrying a higher risk of promoting Antibody-Dependent Enhancement (ADE). ADE is a phenomenon in which suboptimal neutralizing or non-neutralizing cross-reactive antibodies bind to virus and facilitate Fcγ receptor mediated enhanced entry into host cells, followed by its replication, and thus increasing the cellular viral load. On the other hand, antibody responses directed against the host-cell receptor binding domain of DENV envelope domain-III (EDIII), exhibit a higher degree of type-specificity with lower potential of ADE. The challenges associated with whole DENV-based vaccine strategies necessitate re-focusing our attention toward the designed dengue vaccine candidates, capable of inducing predominantly type-specific immune responses. If the designed vaccines elicited predominantly EDIII-directed serotype specific antibodies in the absence of prM and FLE antibodies, this could avoid the ADE phenomenon largely associated with the prM and FLE antibodies. The generation of type-specific antibodies to each of the four DENV serotypes by the designed vaccines could avoid the immune evasion mechanisms of DENVs. For the enhanced vaccine safety, all dengue vaccine candidates should be assessed for the extent of type-specific (minimal ADE) vs. cross-reactive (ADE promoting) neutralizing antibodies. The type-specific EDIII antibodies may be more directly related to protection from disease in the absence of ADE promoted by the cross-reactive antibodies.

They know about this. They know that SARS-like coronaviruses cause ADE, and yet, they're still rushing ahead with vaccinating millions of people. The immune system prefers using old antibodies to making new ones. If you vaccinate someone, you "lock" their immune system into making antibodies specifically against that antigen, so when similar antigens come along, the antibodies from the first one are prioritized.

Shi Zhengli, the "Bat Lady", knew about this. She even helped write a paper on it in late 2019, when her lab in Wuhan was working with MERS:

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

Antibody-dependent enhancement (ADE) of viral entry has been a major concern for epidemiology, vaccine development, and antibody-based drug therapy. However, the molecular mechanism behind ADE is still elusive. Coronavirus spike protein mediates viral entry into cells by first binding to a...

jvi.asm.org

Shi Zhengli, Peter Daszak, and Anthony Fauci are all connected:

https://www.archyde.com/shi-zhenli-and-p-dazak-to-infect-a-person-the-coronavirus-must-be-genetically-modified/

https://timesofindia.indiatimes.com/world/us/top-us-health-advisor-dr-fauci-backed-controversial-wuhan-lab-for-risky-coronavirus-research-report/articleshow/75449844.cms

Read the David E. Martin's dossier on these people:

https://f.hubspotusercontent10.net/hubfs/8079569/The%20FauciCOVID-19%20Dossier.pdf

I've also attached this PDF for archival purposes. Shi Zhengli, Peter Daszak, and Anthony Fauci are mass-murderers and all belong in fucking PRISON!

 

[Salubrious]

Burning man announced they will require proof of vaccine and a negative test for burning man (if it happens) this year.

Isn't Burning Man a multi-day drug fueled orgy basically? But COVID bad?

 

[Ruin]

Isn't Burning Man a multi-day drug fueled orgy basically? But COVID bad?

Yes. It's also absurdly far removed from its hippie roots with tickets being $5000 and up and sponsored by Coca Cola and Intel which I think is hilarious for a "countercultural" festival. Also I think they reversed this but a while back only women were allowed to go full frontal because male nudity was "too threatening."

Tl,dr sjws and corporations ruin everything.