Wuhan Coronavirus: Megathread - Got too big

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Obviously the doctors are not taking enough precautions. Masks? No, no. How about a BSL4 suit?
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If you think all is lost with this nonsense, I wouldn't give in yet. If Alberta can effectively cut the knees off of this there's nothing preventing your state/province from doing the same:

Alberta ends isolation rules as B.C. region mandates masks again

Alberta will no longer require people who test positive for COVID-19 to isolate and will stop routine testing for mild symptoms, as new infections increase and a British Columbia region reimposes measures such as mandatory masking.


Dr. Deena Hinshaw, the province’s Chief Medical Officer of Health, announced the changes on Wednesday as she said it is time to treat COVID-19 as a long-term part of life in Alberta, similar to how the province approaches other respiratory viruses. Alberta will also stop contact tracing except for high-risk settings and masks will no longer be required in schools when classes resume in September.


B.C., meanwhile, reimposed mask requirements in the province’s Okanagan region in response to a spike in cases there. Non-essential travel into the region is being discouraged and activities in nightclubs will be limited.


Alberta has taken the most aggressive approach in the country to moving past COVID-19 measures and became the first in the country to lift almost all of its restrictions.


Most of the changes take effect on Aug. 16.


At the same time, the province is lagging behind the rest of the country on vaccinations. About 76 per cent of eligible Albertans have at least one dose of a vaccine, and 64 per cent of the overall population has at least one dose, both statistics among the lowest in Canada.


COVID-19 cases plummeted after Alberta imposed increased restrictions in May, when it had the highest infection rates in North America. New infections bottomed out in mid-July and are now increasing: the seven-day average for new infections is 142, which has more than doubled in six days.


Hospital admissions have also fallen considerably, with 84 people in hospital as of Tuesday, though that number has increased slightly in recent days.


Dr. Hinshaw said the focus will now be on testing patients with severe illness for whom a positive COVID-19 test could change their treatment, and managing outbreaks in high-risk settings such as long-term care.


She said she understands the changes will seem dramatic, but she said devoting a large proportion of the healthcare system to a single disease is not sustainable. And she said the risks that COVID-19 poses to the population and the healthcare system has changed.



“When we heard of COVID-19, we knew little of the virus and we had no treatments and no vaccines,” she said. “This meant we needed to enact unprecedented measures to protect human life and to prevent our health care systems form being overwhelmed. We have made incredible sacrifices. Today we are in a very different place.”


She noted that nearly all new infections, hospital admissions and deaths involve people who are not vaccinated.


Beginning Wednesday, close contacts of someone who tests positive for COVID-19 will no longer be required to isolate, regardless of their vaccination status, and contact tracing will be limited to cases involving high-risk settings.


On Aug. 16, anyone who tests positive for COVID-19 will no longer be required to isolate, though people with symptoms will still be encouraged to stay home. Testing will be limited to cases in which the result could affect patient care; the province will shut down its mass testing sites at the end of August and instead shift testing to doctor’s offices and acute care facilities.


Health officials will respond to outbreaks in schools and daycares with similar measures that would be used for other respiratory illnesses. Masks won’t be required in schools but recommended during outbreaks.


Since the province will be conducting significantly fewer COVID-19 tests, it will use wastewater testing to monitor the level of spread in the community.


Edmonton infectious disease physician Leyla Asadi said she was shocked to learn of the changes announced on Wednesday, which she said were “a big gamble” and premature.


“There’s nowhere else in Canada that is taking these measures,” Dr. Asadi said. “And we’re so close to being at a point where we can safely move on – if we can minimize the fourth wave and get to a point where children can also be vaccinated, and where we can increase the vaccine uptake in the general population, then we could really have peace of mind.”


She was particularly concerned with the decision to scale back on testing and contact tracing.


“One of the most basic measures you can implement is if an individual tests positive, that they should be isolating and ... their close contacts should be in quarantine,” she said.


“It’s the lifting of those measures that is really, really reckless.”


Anand Kumar, an infectious disease physician in Winnipeg and professor at the University of Manitoba, also said the changes were happening too soon.


“I know that politicians want to be done with COVID, but COVID isn’t done with us,” Dr. Kumar said.


He noted some pockets of the province have low vaccination rates, and the timing of the lifting of measures in Alberta – combined with a recent increase in cases – could lead to a COVID-19 surge when schools resume in September.


“I think you’re going to see very substantial activity in terms of COVID in schools. I think you’re going to see a lot more kids in hospital, and in ICU.”


Alberta NDP Deputy Leader Sarah Hoffman said the government is getting rid of the systems that have kept people safe from COVID-19 too soon, before the province has a chance to see what the return to classrooms looks like.


“I’m concerned about the removal of notification requirements, and that a child could be infected with COVID-19, could go to school, could spread it to their classmates, and no one would be any the wiser,” said Ms. Hoffman, noting the start of the school year is just four weeks away.


Meanwhile in B.C., health officials are reinstating mandatory masking in the Okanagan region after an outbreak led to rapidly spreading infection driven primarily by unvaccinated residents between the ages of 20 and 40.


Sue Pollock, the chief medical health officer for Interior Health, said that starting at midnight Wednesday, masks will be mandatory in all indoor public places in central Okanagan communities including Peachland, West Kelowna, Kelowna, Lake Country and Westbank First Nation. Gyms and exercise facilities must also require patrons to wear masks and reintroduce enhanced cleaning and physical distancing.


A number of businesses in the central Okanagan have been forced to close due to illness so enforcement involving bylaw officers, WorkSafeBC and local officials will be increased as they follow up with establishments where three or more cases of COVID-19 have occurred, Dr. Pollock said.


Provincial health officer Dr. Bonnie Henry said the new measures should send a message about the importance of immunization, especially as more transmissible variants can lead to clusters among people who are not vaccinated, she said.

The TL;DR is Alberta is ending all major pandemic monitoring and restrictions and shifting to the annual flu strategy. Quarantining is now only recommended if you catch it (not required), testing is being drastically scaled back in favour of water testing, and hospital reporting as branch-covidians know it is effectively over. Incredibly surprised to see it, the comment sections on this and related articles is about as you'd expect, but very damn happy to actually see happen somewhere in Canada what should've been implemented everywhere earlier this year.

Also there's going to be a hilarious amount of salt to mine when the fearmongering about Alberta's upcoming apocalyptic wave of death doesn't materialize and the fall/winter covid numbers show absolutely nothing because all that testing no longer happens. Guess BC and Ontario will have to pick up the slack on that front :story:
 
Yeah fuck Fauci and the Branch Covidians that enable this shit; but this isn't true.
There is no reason why viral load would be higher in vaccinated versus unvaccinated.
There is one possible reason why the vaccinated would have a higher viral load than the unvaccinated, and it's Antibody-Dependent Enhancement, or ADE. Antibody-Dependent Enhancement occurs when the body produces incompletely neutralizing antibodies against infection due to a prior immune response against a similar pathogen. This causes the still-live, incompletely neutralized virus to use an attached antibody to hitch a ride into a macrophage via the Fc pathway, and then infect that macrophage and replicate inside it. In other words, ADE gives a virus another host receptor that allows it to infect, replicate in, and kill immune cells that it wouldn't have been able to infect previously.



Antiviral antibodies promote viral infection of target immune cells by exploiting the phagocytic FcγR or complement pathway.[4] After interaction with the virus the antibody binds Fc receptors (FcR) expressed on certain immune cells or some of the complement proteins. FcγR binds antibody via its fragment crystallizable region (Fc). Usually the process of phagocytosis is accompanied by the virus degradation, however, if the virus is not neutralized (either due to low affinity binding or targeting to a non-neutralizing epitope), antibody binding might result in a virus escape and therefore, enhanced infection. Thus, phagocytosis can cause viral replication, with the subsequent death of immune cells. The virus “deceives” the process of phagocytosis of immune cells and uses the host's antibodies as a Trojan horse. ADE may occur due to the non-neutralizing characteristic of the antibody, which bind viral epitopes other than those involved in a host cell attachment and entry. ADE may also happen due to the presence of sub-neutralizing concentrations of antibodies (binding to viral epitopes below the threshold for neutralization).[5] In addition ADE can be induced when the strength of antibody-antigen interaction is below the certain threshold.[6][7] This phenomenon might lead to both increased virus infectivity and virulence. The viruses that can cause ADE frequently share some common features such as antigenic diversity, abilities to replicate and establish persistence in immune cells.[1] ADE can occur during the development of a primary or secondary viral infection, as well as after vaccination with a subsequent virus challenge.[1][8][9] It has been observed mainly with positive-strand RNA viruses. Among them are Flaviviruses such as Dengue virus,[10] Yellow fever virus, Zika virus,[11][12] Coronaviruses, including alpha- and betacoronaviruses,[13] Orthomyxoviruses such as influenza,[14] Retroviruses such as HIV,[15][16][17] and Orthopneumoviruses such as RSV.[18][19][20]


Antibody-dependent enhancement (ADE) of viral entry has been a major concern for epidemiology, vaccine development, and antibody-based drug therapy. However, the molecular mechanism behind ADE is still elusive. Coronavirus spike protein mediates viral entry into cells by first binding to a receptor on the host cell surface and then fusing viral and host membranes. In this study, we investigated how a neutralizing monoclonal antibody (MAb), which targets the receptor-binding domain (RBD) of Middle East respiratory syndrome (MERS) coronavirus spike, mediates viral entry using pseudovirus entry and biochemical assays. Our results showed that MAb binds to the virus surface spike, allowing it to undergo conformational changes and become prone to proteolytic activation. Meanwhile, MAb binds to cell surface IgG Fc receptor, guiding viral entry through canonical viral-receptor-dependent pathways. Our data suggest that the antibody/Fc-receptor complex functionally mimics viral receptor in mediating viral entry. Moreover, we characterized MAb dosages in viral-receptor-dependent, Fc-receptor-dependent, and both-receptors-dependent viral entry pathways, delineating guidelines on MAb usages in treating viral infections. Our study reveals a novel molecular mechanism for antibody-enhanced viral entry and can guide future vaccination and antiviral strategies.

Bonus points; one of this article's authors is the Bat Lady herself.


Original antigenic sin, also known as antigenic imprinting or the Hoskins effect,[1] refers to the propensity of the body's immune system to preferentially utilize immunological memory based on a previous infection when a second slightly different version of that foreign pathogen (e.g. a virus or bacterium) is encountered. This leaves the immune system "trapped" by the first response it has made to each antigen, and unable to mount potentially more effective responses during subsequent infections. Antibodies or T-cells induced during infections with the first variant of the pathogen are subject to a form of original antigenic sin, termed repertoire freeze.

The phenomenon of original antigenic sin has been described in relation to influenza virus, dengue fever, human immunodeficiency virus (HIV) [2] and to several other viruses.[3]

This phenomenon was first described in 1960 by Thomas Francis Jr. in the article "On the Doctrine of Original Antigenic Sin".[4][5] It is named by analogy to the theological concept of original sin. According to Thomas Francis, who originally described the idea,[4] and cited by Richard Krause:[5]


(Questions are bolded)

If we look at the curve from the WHO, since the vaccinations started in January, the curve showing new infections (contamination) has exploded, along with deaths.

Notably among young people.


—Yes. With thromboses, etc.

How do you view the mass vaccination program? Mass vaccination compared to treatments that work and aren’t expensive.

—It’s an enormous mistake, isn’t it? A scientific error as well as a medical error. It is an unacceptable mistake. The history books will show that, because it is the vaccination that is creating the variants.

—For the China virus, there are antibodies, created by the vaccine. What does the virus do? Does it die or find another solution?

—The new variants are a production and result from the vaccination. You see it in each country, it’s the same: the curve of vaccination is followed by the curve of deaths.

—I’m following this closely and I am doing experiments at the Institute with patients who became sick with Corona after being vaccinated. I will show you that they are creating the variants that are resistant to the vaccine.

Should we be vaccinating during a pandemic?

—It’s unthinkable.

—They’re silent… many people know this, epidemiologists know it.

—It is the antibodies produced by the virus that enable an infection to become stronger.

—It’s what we call Antibody Dependent Enhancement, which means antibodies favor a certain infection. The antibody attaches to the virus, from that moment it has the receptors, the antibodies, we have them in the macrophage etc.

—It pokes the virus and not accidentally, but because of the fact that they’re linked to the antibodies.

—It is clear that the new variants are created by antibody-mediated selection due to the vaccination. OK?

If COVID-19 vaccines cause ADE, it wouldn't be the first time that a vaccine has enhanced disease. In fact, this occurred five years ago with Dengvaxia in the Philippines:


 
My family is just getting really antsy about this disease every time they hear just how many new cases are popping up on ABC World News Tonight. Heck, just hearing about Florida having 500 new cases pop up in a day is really nerve-wracking.
 
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A young girl, about age 9 or 10, sat on a chair surrounded by health officials. She wore a bright yellow T-shirt with the words "Dengue is dangerous" across it. She squeezed her eyes and bit her lip as the health secretary of the Philippines, Dr. Janette Garin, gave her a shot in the arm.

That shot launched a massive vaccine campaign to inoculate nearly 1 million schoolchildren with Dengvaxia.
She has also advocated for women's issues, including pushing for the passage of the Responsible Parenthood and Reproductive Health Act of 2012.

Garin was elected as the first Filipino board member to the Parliamentary Network on the World Bank
 
My family is just getting really antsy about this disease every time they hear just how many new cases are popping up on ABC World News Tonight. Heck, just hearing about Florida having 500 new cases pop up in a day is really nerve-wracking.
Ever notice how they never announce deaths. I'd be interested in hearing how many of those 500 die.

Again, if people weren't fear-mongered into taking a COVID test every time they have a sniffle we wouldn't be hearing about this.

Shit, if nobody ever brought up COVID from the very beginning of this outbreak we wouldn't even have noticed a difference. It would just be brushed off as a typical Flu season.
 
Also there's going to be a hilarious amount of salt to mine when the fearmongering about Alberta's upcoming apocalyptic wave of death doesn't materialize and the fall/winter covid numbers show absolutely nothing because all that testing no longer happens. Guess BC and Ontario will have to pick up the slack on that front :story:
It gets memory-holed, just like the endless screeching about Georgia in April 2020 and then Florida a month or two later and then Texas this year is followed by nothing but silence aside from "well look how many people are dying there, at least when they die in New York or California the government is doing their best!" Or you know, Sweden, which is always ignored except when they can point out that Sweden has slightly more cases and deaths despite their citizens being the most free in all of Europe.

There was never any sane reason to draw this out later than June/July 2020 (and I say that, imagining myself as a typical politician who wants to be cautious), aside from maybe shit like securing nursing homes and elderly people against the disease. They've stolen almost 18 months of our lives for no good reason.
Ever notice how they never announce deaths. I'd be interested in hearing how many of those 500 die.

Again, if people weren't fear-mongered into taking a COVID test every time they have a sniffle we wouldn't be hearing about this.

Shit, if nobody ever brought up COVID from the very beginning of this outbreak we wouldn't even have noticed a difference. It would just be brushed off as a typical Flu season.
It would've been like the 2017 flu season which was much worse than normal, but not as bad as the last "pandemic" in 2008. "Wow, the flu sure is bad this year, I felt fucking awful when I caught it!" I mean there's a reason the last time we had a coronavirus pandemic back in 1889-90 that it was called a flu pandemic until like a decade ago when biologists did some analysis and realized it might've been like SARS/a coronavirus since there's a coronavirus in humans that causes a typical cold that emerged in the late 19th century.
 
Ever notice how they never announce deaths. I'd be interested in hearing how many of those 500 die.

Again, if people weren't fear-mongered into taking a COVID test every time they have a sniffle we wouldn't be hearing about this.

Shit, if nobody ever brought up COVID from the very beginning of this outbreak we wouldn't even have noticed a difference. It would just be brushed off as a typical Flu season.
Florida actually had a really high death count on Tuesday: 92. On average Florida is at about 40 deaths right now.

For reference, the entire US is at approximately 300 deaths per day from COVID according to the CDC. New York State is at 5 deaths per day, at least half coming from NYC.

Yes, I am aware how absurdly low these numbers are for this CDC reaction. In comparison, 300 people die every day in the US from Alzheimers. COVID is as deadly as Alzheimers right now despite the latter only really affecting the super old.

CDC Covid Deaths Florida 2021-07-29.png

 
Ever notice how they never announce deaths. I'd be interested in hearing how many of those 500 die.

Remember that woman in her 30's who the Australian government proclaimed died of Covid last week. Without any underlying health issues.
During a press conference they were asked if she got the vaccine (as her friends said she got the jab before getting diagnosed) and the health chief said she would find out her vaccination status.

The government have gone quiet about it, and no mainstream media outlet has been commenting on it.

If it turns out she got the jab, it's just going to blow up in their faces. Especially since she had emergency surgeries for clotting..
 
There was never any sane reason to draw this out later than June/July 2020 (and I say that, imagining myself as a typical politician who wants to be cautious), aside from maybe shit like securing nursing homes and elderly people against the disease. They've stolen almost 18 months of our lives for no good reason.
I wouldn't be surprised if it was drawn out in order to get people to lose faith in Trump due to his handling of the whole situation. Heck, when I told my parents about how the economy did pretty good under his presidency, they immediately countered with how poor it became thanks to COVID-19.
 
My family is just getting really antsy about this disease every time they hear just how many new cases are popping up on ABC World News Tonight. Heck, just hearing about Florida having 500 new cases pop up in a day is really nerve-wracking.
Tell them the pandemic was over in Feb 2021

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See that big dip in Feb? The Delta variant is 10 times less deadly than that.

Meantime down under


New powers have been granted to the NSW police commissioner to shut down businesses, construction sites and public premises where there is a risk to public health.

Mick Fuller said on Thursday afternoon he had also requested the assistance of the Australian Defence Force.

“The NSW police force is significantly expanding its enforcement activities in Sydney over the coming days and has requested 300 ADF personnel to boost its operational footprint,” the commissioner said.

“The assistance of the ADF has been essential over the past 18 months – particularly during last year’s border operation, the ongoing hotel quarantine operation and the assistance provided with logistics support in the police operations centre.”

The state’s police minister, David Elliott, said “support from the army will add another line of defence to the NSW government’s crackdown on Covid-19 compliance”.

The federal health minister, Greg Hunt, subsequently said the commonwealth would “willingly comply” with the NSW request for boots on the ground.

“The ADF played a critical role in Victoria, the boots on the ground were here to help people, they assisted with compliance, they actually provided confidence,” Hunt said on Thursday. “That will provide additional support to the police and additional help for the people of NSW.”

They're turning the working class areas of Sydney into a full blown police state. The police have been granted pretty much unlimited powers and they've called in the army to patrol the streets. This is making the Melbourne lockdown look like a children's party.

They're doing this to control a viral outbreak that now has a lower mortality rate than the seasonal flu.

Can someone please wake me up when the rest of the world comes to it's senses?
 
Water is also a good thing to have instead of anything else that's filling in a bad way such as junk food.

Something like Seven Oceans ration bars are good. High calorie, like 2,000 a biscuit, small, light and easily portable. Sure they're not "inspiring" to eat, but those, some water and multivitamins will do in a pinch for a few days.
 
John Daniel, MD, MS

Lol. He lists his MS as a brag in his twitter bio. To people that are unaware, if you're a retard who can't get accepted to any medical schools out of their undergrad (mostly due to a shit GPA, a really shit MCAT score, or some combo of these along with bad extra curriculars), they'll usually do a 1 year Masters of Science program that's essentially to just juice their GPA and pad their resume and try again to get into Medical School. (These sorts of MS programs usually have little/no research component, so it's just a bunch of mark padding courses, no dissertation required).

So, it's funny he's using that to brag, when to anyone involved in Medicine it shows you're a dumb dumb who couldn't get in on their first pass.
 
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