Speaking as an ex-OG Brony here.
As a whole, the MLP:FIM fandom corrupts whatever it touches. Period. I speak from personal experience.
You can start out with the purest, best of intentions as an artist, but once the fandom as a whole latches onto your creations, It's less than a matter of days before you light-hearted innocent work is the subject of someone else's fap material. Fluffle Puff is a prime example of this. I've known more than a few serious artists that ran away screaming because it wasn't 24 hours before their first MLP cartoon/plushie/whatever was turned into incestual scat inflation porn on Ponybooru.
Reason #2 why I left the fandom.