The only reason Lou doesn't use charm or wit is because he's too stupid to pull it off. He certainly tries, (remember when he attempted karma farming on Reddit a few weeks back to try to get into the e-begging subreddits?) but his attempts to do so are transparent and fail. If you want to see what a less stupid Lou would look like, check out Kevin Gibes, a cow Lou greatly resembles but is not intellectually sub-normal (KevKev certainly isn't a genius, but he's not borderline retarded like Lou), and that level of cunning allows him to extend his tendrils into trans Twitter, to enable him to extract money from them and groom vulnerable people for his own sexual gratification. Lou wishes he could do that, and certainly tries, but he's too stupid to understand people well enough to manipulate them on a more sophisticated level than "hungry, tell lie for food money".
Remember that ASPD is *not* the same as sociopathy/psychopathy, though they often occur together. Sociopaths and Psychopaths learn from their mistakes and develop more sophisticated plans, methods and goals, but ASPD is characterised by not learning from your mistakes and repeating the same patterns of behaviour even when they backfire on you, which is what Lou does. Sociopaths don't behave recklessly or without regard to their own health/safety because self-preservation is important to them, ASPD people aren't that sophisticated. Lou acts without any regard to his own safety, especially when it comes to his diet and health. That's why I think Lou has ASPD but not sociopathy, psychopathy, or even Autism.
Lou is clearly intellectually very subnormal, but that's a separate issue. But if Kevin Gibes is anything to go by, we should be fortunate that Lou isn't smarter, because he would be quite dangerous to vulnerable people if he was.