Wuhan Coronavirus: Megathread - Got too big

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Do you realize what kind of measures healthcare is taking now to make sure that MRSA stays more or less within hospitals and doesn't go outside?
Not enough, because Lucas Werner is still wandering the streets.

Soldiers of the german Bundeswehr reject mandatory vaccination against Covid - Minister of Defense tells them to go fuck themselves, introduces mandatory vaccination against Covid
Krauts gonna kraut.

Another argument against the theory of all vaxxed dropping dead within the next 2-5 years:
now that the soldiers are getting jabbed, would TPTB risk losing the military? Who is going to defend them against the masses if shit were to hit the fan? Them being sick when they're old is ok, though, they're already retired by then.
I don't disagree and I don't follow the "vaxxed dead in 3 years!" conspiracy theory, BUT, the military is also one of the biggest forces that could overthrow them.
Its why dictators purge their military ranks all the fucking time and fill the officer corps with hapless yes-men.
 
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isreal question keep winning
it worst to get 3rd booster shot than it is to get 2shoots
 
They'll just start churning out scary sounding names. "The Super Mega Delta Death Ray variant is the deadliest yet, quick everyone get into your bunker, but not before getting your science juice!!!!".
"You need 6 doses of Pfizer boosters daily to protect against the Voldemort-First Order-Thanos Variant!"

The production of neutrailising antibodies is a response to infection. This can never provide long term immunity to mutable RNA viruses like SARS Cov-2. Mammalian immune systems prioritise memory immunity as it's more efficient. From everything to the common cold, seasonal flu and Covid-19 T-cell immunity is literally all that matters. Neutralising antibodies from RNA viral exposure will almost always dissipate with time, this is entirely to be expected.
So this *mostly* true.
T-cells are extremely important because they destroy infected/"hijacked" cells, and thus slow and eventually halt the production of new viral particles.
However, that neglects the role of other immune responses in fighting off an infection. B-cells are still important because they remember the best antibody "recipe" for different pathogens, which could be anything from pollen to viruses to to snake venom proteins. Antibodies themselves are important because they bind to and neutralize the pathogen before it impacts the cell. In the case of viral infections, interferons are also important. If a virus is like the cell's hijackers, then interferons are like the cell's Flight 93 passengers - basically stalling, thwarting or sabotaging viral replication from inside the cell until a T-cell can get there and nuke it.

Now, the problem is the "experts" seem obsessed with antibody counts, and only antibody counts. Worse yet, they are obsessing over antibodies for only one of at least a dozen different viral proteins (at least one of three found on the surface).
 
They've been milking Delta for a full year, most people don't realise it's the same as the Indian Variant. Maybe they'll just rename it again.

The vaccine passes are working well, now they're talking about restricting who you can have in your own home again (lol good luck with that) and making primary school children wear masks.

Worse than the Nazis or Soviets ever thought about being.
 
Worse than the Nazis or Soviets ever thought about being.
Yeah okay fuck the vaxfags and the branch covidians in power, fuck them to hell for their pushing this shit on kids, but this is a bit of a stretch.

Nazis burned children alive and experimented on pregnant women, while Soviets gulag'ed entire families and NKVD was run by literal pedophiles who'd disappear you if you complained about the pedophilia.
 
Is this the immune escape variant we have been waiting for?



The variant is called B.1.1.529 and is likely to be given a Greek code-name (like the Alpha and Delta variants) by the World Health Organization on Friday.

Who wants to take a stab in the dark at its name?

It is also incredibly heavily mutated. Prof Tulio de Oliveira, the director of the Centre for Epidemic Response and Innovation in South Africa, said there was an "unusual constellation of mutations" and that it was "very different" to other variants that have circulated.

"This variant did surprise us, it has a big jump on evolution [and] many more mutations that we expected," he said.

In a media briefing Prof de Oliveira said there were 50 mutations overall and more than 30 on the spike protein, which is the target of most vaccines and the key the virus uses to unlock the doorway into our body's cells.

Zooming in even further to the receptor binding domain (that's the part of the virus that makes first contact with our body's cells), it has 10 mutations compared to just two for the Delta variant that swept the world.

This level of mutation has most likely come from a single patient who was unable to beat the virus.

They were unvaxxed, obvs.

It is still early to draw clear conclusions, but there are already signs that are causing worry.

There have been 77 fully confirmed cases in Gauteng province in South Africa, four cases in Botswana and one in Hong Kong (which is directly linked to travel from South Africa).

However, there are clues the variant has spread even more widely.

This variant seems to give quirky results (known as an S-gene dropout) in the standard tests and that can be used to track the variant without doing a full genetic analysis.

That suggests 90% of cases in Gauteng may already be this variant and it "may already be present in most provinces" in South Africa.

But this does not tell us whether it spreads faster than Delta, is any more severe or to what extent it can evade the immune protection that comes from vaccination.

Gee. Don't really tell us much, do they? Just more fearmongering.
 
"You need 6 doses of Pfizer boosters daily to protect against the Voldemort-First Order-Thanos Variant!"


So this *mostly* true.
T-cells are extremely important because they destroy infected/"hijacked" cells, and thus slow and eventually halt the production of new viral particles.
However, that neglects the role of other immune responses in fighting off an infection. B-cells are still important because they remember the best antibody "recipe" for different pathogens, which could be anything from pollen to viruses to to snake venom proteins. Antibodies themselves are important because they bind to and neutralize the pathogen before it impacts the cell. In the case of viral infections, interferons are also important. If a virus is like the cell's hijackers, then interferons are like the cell's Flight 93 passengers - basically stalling, thwarting or sabotaging viral replication from inside the cell until a T-cell can get there and nuke it.

Now, the problem is the "experts" seem obsessed with antibody counts, and only antibody counts. Worse yet, they are obsessing over antibodies for only one of at least a dozen different viral proteins (at least one of three found on the surface).
B-cell recall is the immune system 'remembering' a past exposure and triggering neutralising antibody production when challenged by a pathogen which will either prevent replication of a virus or ensure a mild disease progression. The likeliest reason that children are not suffering serious disease from Covid, besides having strong immune systems, is that they've been primed to fight off Covid from recent exposure to other circulating respiratory viruses. Children catch colds frequently, it's important that they do as it builds their immune memory. Cross immunity is definitely a factor in preventing Covid infection. Note that children were not even catching the virus last year but now they are. I think that's down to keeping them locked up at home for over a year and not allowing them to mix. Yet another reason that extended lockdowns are stupid and dangerous for public health. Now they're back at school they're not showing as strong a resistance to infection but thankfully are not suffering serious disease from the virus.

Is this the immune escape variant we have been waiting for?





Who wants to take a stab in the dark at its name?



They were unvaxxed, obvs.



Gee. Don't really tell us much, do they? Just more fearmongering.
The last scary vaccine resistant variant was also from South Africa, the Beta strain. It was eventually out competed by the Delta variant and died off. The theory is that the large number of HIV positive people in South Africa is allowing for higher viral mutation to occur due to immunocompromised people displaying an abnormal immune response to infection. Weaker immune systems not able to produce enough neutralising antibodies and the virus having more time to mutate around them. Of course the same could be said for the vaccinated.

We'll see what happens. If a vaccine resistant variant does take off it will be a disease that overwhelmingly effects the vaccinated. The competitive advantage of this new variant is not going to come from transmissiblity. However even if it's not as easy to catch as Delta Covid it still might be able to out compete it if it can bypass the vaccine derived S-antibodies altogether, which Beta Covid was unable to do (plus there being way less vaccinated at the time to circulate among). We'll know when we start seeing the purebloods mainly catching Delta Covid and the vaccinated catching the new strain a process that will only be exacerbated if they double down on keeping the vaxxed and unvaxxed separated. People need to accept that having a large percentage of the population with broad and robust natural immunity is the only way we will move on from this. I'm not holding my breath.
 

New COVID variant: UK urgently brings in travel restrictions to stop spread of 'the worst one we've seen so far'​

Mutations in the B.1.1.529 variant are likely to evade the immune response generated by prior infection and vaccination, UK experts say.

Britain is bringing in travel restrictions for six African countries due to a new COVID variant that UK experts have called the "worst one we've seen so far".

Health Secretary Sajid Javid tweeted: "UKHSA (UK Health Security Agency) is investigating a new variant. More data is needed but we're taking precautions now.

"Six African countries will be added to the red list, flights will be temporarily banned, and UK travellers must quarantine."

Mr Javid said the new B.1.1.529 variant identified in South Africa "may be more transmissible" than the Delta strain - and warned "the vaccines that we currently have may be less effective".

The UKHSA says it is the "worst one we've seen so far" and has a spike protein that is "dramatically" different to the original COVID strain.

The variant also has 30 mutations - twice as many as the Delta variant - and these mutations are likely to evade the immune response generated by prior infection and vaccination.

But the good news is that B.1.1.529 can be detected with a normal PCR test.

Flights from South Africa, Namibia, Lesotho, Botswana, Eswatini and Zimbabwe will be suspended from 12pm on Friday - and after 4am on Sunday, new arrivals in the UK will be required to quarantine in hotels.

No cases of this variant have been reported so far in the UK, and anyone who has travelled from one of these countries in the past 10 days is now being invited to come forward for a test.

About 500 to 700 people are travelling to the UK from South Africa each day at the moment, but it is expected this figure could increase in the run up to Christmas.

According to aviation analyst Alex Macheras, Virgin Atlantic had reported taking more than 32,000 bookings for South Africa in October alone - and most of them for the rest of 2021.

Tom Peacock, a virologist at Imperial College London, described the mutations as "really awful" but said cases were currently "super low".

Spike proteins are what viruses use to get into human cells, and some vaccines work by training the body to recognise the spikes and neutralise them.

Mutations on the spike could therefore potentially prove problematic.

But with only a handful of recorded cases - three in Botswana, around 53 in South Africa and one in Hong Kong from someone who had travelled from South Africa - scientists are hopeful it can be contained.

Francois Balloux, professor of computational systems biology at University College London, said it should be closely monitored but "there is no reason to get overly concerned, unless it starts going up in frequency in the near future".

In South Africa, the coronavirus variant has spread rapidly among young people in Gauteng, the country's most populous province.

"Over the last four or five days, there has been more of an exponential rise," South Africa's health minister Joe Phaahla said.

Until recently, the country had been reporting about 200 confirmed cases per day - but this has rapidly increased over the past week, hitting 2,465 on Thursday.

Scientists from seven South African universities are now studying the variant, and are trying to determine how many of these new cases are linked to it.

Ravindra Gupta, professor of clinical microbiology at the University of Cambridge, has warned "there is a high probability" that many of the new cases in South Africa are linked to the new variant.

Just 41% of South African adults have been vaccinated and 130,000 jabs are being administered per day - well below the target of 300,000 set by the government.

The country is currently getting deliveries of vaccines faster than they can be used, meaning that officials have been deferring deliveries so they don't "accumulate and stockpile" vaccines.

World Health Organisation experts are meeting on Friday to assess the variant, which on Wednesday was classed a variant under monitoring.

If it is upgraded to a variant of concern, it could be given a name from the Greek alphabet - and would likely be referred to as Nu.

However, it could also be classed as a less serious variant of interest, indicating it has characteristics that may affect factors such as transmissibility and disease severity.

It could take weeks to generate all the information needed about this variant's characteristics.

To date, the Delta variant remains by far the most infectious - and it now accounts for more than 99% of the sequences submitted by countries worldwide.


 
Ever since I had my two shots I have always a clogged nose and have a terrible sleep. No chest pain… yet.
I fucking regret everything, if die because of those shots then it’s another dumbass dying because of family pressure. No booster for me though, fuck you dad!
Your immune system will eventually recover as long as you stop getting jabbed. The side effects are an unknown factor. I understand that there have been bad batches of vaccine that produce the most adverse events. There's ways you can check this if you're worried. On top of this introducing spike protein systemically was always a terrible idea as it's a toxic substance to the human body.

You're going to catch Covid. I'm going to catch Covid, Almost everyone alive is going to catch Covid. If you catch Delta Covid and you still have circulating S-antibodies you will have a mild disease, but unvaxxed people in good health will also have a mild disease so you've gained no benefit as the virus is a nothing burger to the healthy. You will likely not gain proper immunity after you recover from Covid though and you'll be far more prone to re-infection. OAS in the vaxxed is all but confirmed at this point and it's why we're seeing such crazy high case numbers in Europe, the number of susceptible people is not reducing as it would with natural immunity. But again this effect will likely wear off with time as long as you decline the booster. What you don't want is to have circulating s-antibodies and be infected by a vaccine resistant variant, that might end up being really, really bad. Remember that the whole reason they didn't bother to reformulate the vaccines for Delta Covid is because they knew that OAS was a thing and so there was no point.
 
B-cell recall is the immune system 'remembering' a past exposure and triggering neutralising antibody production when challenged by a pathogen which will either prevent replication of a virus or ensure a mild disease progression. The likeliest reason that children are not suffering serious disease from Covid, besides having strong immune systems, is that they've been primed to fight off Covid from recent exposure to other circulating respiratory viruses. Children catch colds frequently, it's important that they do as it builds their immune memory. Cross immunity is definitely a factor in preventing Covid infection. Note that children were not even catching the virus last year but now they are. I think that's down to keeping them locked up at home for over a year and not allowing them to mix. Yet another reason that extended lockdowns are stupid and dangerous for public health. Now they're back at school they're not showing as strong a resistance to infection but thankfully are not suffering serious disease from the virus.
Yeah so the thing is that COVID isn't actually that deadly on its own.
You don't need to explain why kids weren't getting sick from COVID with cross-immunity, they weren't getting sick because its not that symptomatic or deadly.

I don't know about the rest of the world, but part of what happened in the US was that shit like RSV and enteroviruses were running rampant in schools after the lockdown (gee moosks sure work, huh?). Kids are hardly getting sick from COVID, they're getting sick from shit that makes kids sick, then testing positive for COVID.
 
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