Science Japanese scientists develop vaccine to eliminate cells behind aging

Japanese scientists develop vaccine to eliminate cells behind aging

The vaccine enables the body to create antibodies that attach themselves to senescent cells, which are removed by white blood cells.

www.japantimes.co.jp

Japanese scientists develop vaccine to eliminate cells behind aging |…

archived 12 Dec 2021 17:24:12 UTC

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A Japanese research team said it developed a vaccine to remove so-called zombie cells that accumulate with age and damage nearby cells, causing aging-related diseases including arterial stiffening.
The team, including Juntendo University professor Toru Minamino, confirmed that mice administered with the vaccine showed decreases in the zombie cells, medically known as senescent cells, and in areas affected by arterial stiffening.

“We can expect that (the vaccine) will be applied to the treatment of arterial stiffening, diabetes and other aging-related diseases,” Minamino said.
The results of the team’s research were published in the online version of the journal Nature Aging on Friday.
Senescent cells refer to those that have stopped dividing but do not die. They damage nearby healthy cells by releasing chemicals that cause inflammation.
The team identified a protein found in senescent cells in humans and mice and created a peptide vaccine based on an amino acid that constitutes the protein.
The vaccine enables the body to create antibodies that attach themselves to senescent cells, which are removed by white blood cells that adhere to the antibodies.
When the team administered the vaccine to mice with arterial stiffening, many accumulated senescent cells were removed and areas affected by the disease shrank. When administered to aged mice, their frailty progression was slower than that of unvaccinated mice, according to the team.
Many of the existing drugs to remove senescent cells are used as anti-cancer agents and may cause negative side effects. Side effects from the new vaccine were fewer, while its efficacy lasted longer, the team said.

 

[Clotso Coof]

I've seen enough zombie movies to know how this ends.

 

[SSj_Ness (Yiffed)]

As if commoners will be allowed anywhere near such a medicine. In fact it probably already exists and only a select few are privilege to it.

They want less commoners, not more, and certainly they don't need us healthy and long lived.

 

[Look over there]

As if commoners will be allowed anywhere near such a medicine. In fact it probably already exists and only a select few are privilege to it.

They want less commoners, not more, and certainly they don't need us healthy and long lived.

They'll make it prohibitively expensive, so only billionaires can get it. Eventually once morals decay enough, we might see a Running Man/Squid Game style deal for people to win it.

 

[Kermit Jizz]

Ok, how do you stop the degradation of DNA? This is just buzzword title that means nothing.

 

[Secret Asshole]

This headline is pretty misleading. These aren't cells that cause aging, these are aged cells. Senescence literally means biologically aged. These cells are basically beyond the divisional limit and divide extremely slowly or don't divide anymore. This won't stop cells from aging, but will clear out aged cells so other cells might divide and not be senescent. It does not prevent cellular aging or divisional limits, this is just a treatment for certain disorders.

 

[Ly Erg]

This headline is pretty misleading.

A misleading headline made to draw up views and kiwis not reading beyond the headline is something you can't prevent with a vaccine.

 

[Permuto]

All I want is to look like and have the health of a 20-30 year old when I'm 120 and have a hot android spouse with a sex and combat mode including built in laser canons. I was born in the wrong generation.

 

[The handsome tard]

Wasnt the T-Virus made with the intention of stopping aging or something like that?

Boi, I would hate to be a small "town" american city right now.

It's like they're trying to recreate Palpatine in that he had no plans of ever giving up power.

They will live forever and we will all suffer for it.

Palpatine WAS meant to be one of those elites but with actual magical powers. George Lucas knew what he was doing.

 

[IKOL]

Fuck up. Seriously. We need the aged rich to die off naturally as intended, I'm genuinely terrified of giving desperate, rotted ghouls a means to stave off what they deserve any longer.

don't be afraid, most of the body cells may go trough this, but brain is still a very fragile thing, sooner or later they'll hit dementia or cancer anyway. or something worse.

 

[theshitposter]

where are the antivaxxers now?

 

[Overly Serious]

This headline is pretty misleading. These aren't cells that cause aging, these are aged cells. Senescence literally means biologically aged. These cells are basically beyond the divisional limit and divide extremely slowly or don't divide anymore. This won't stop cells from aging, but will clear out aged cells so other cells might divide and not be senescent. It does not prevent cellular aging or divisional limits, this is just a treatment for certain disorders.

Good avatar-comment synergy. I read that in David's voice. Perfect organism coming up!

where are the antivaxxers now?

Trying to achieve long-life the traditional way - by not having heart attacks.

 

[PS1gamenwatch]

I've seen enough zombie movies to know how this ends.

I thought this was how Deep Blue Sea started

 

[Troonologist PhD]

A Japanese research team said it developed a vaccine to remove so-called zombie cells that accumulate with age and damage nearby cells, causing aging-related diseases including arterial stiffening.
...
We can expect that (the vaccine) will be applied to the treatment of arterial stiffening, diabetes and other aging-related diseases,” Minamino said.

 

[Return of the Freaker]

All the universe is a cycle. Even the most well meaning attempts to break it will plunge everything into darkness

 

[Plumber's Kokoro Wish]

Fuck up. Seriously. We need the aged rich to die off naturally as intended, I'm genuinely terrified of giving desperate, rotted ghouls a means to stave off what they deserve any longer.

My thoughts as well, surely the powers at be would never put an age defying medicine in the hands of common people, this will only be for the powerful and wealthy.

 

[BlerdBjern]

As if commoners will be allowed anywhere near such a medicine. In fact it probably already exists and only a select few are privilege to it.

They want less commoners, not more, and certainly they don't need us healthy and long lived.

As long as they continue to require more money they need us.

Besides this is another source of revenue, they would sqYeezy everything they can out of it.

 

[keyboredsm4shthe2nd]

Fuck up. Seriously. We need the aged rich to die off naturally as intended, I'm genuinely terrified of giving desperate, rotted ghouls a means to stave off what they deserve any longer.

Nancy Pelosi's still got a secure supply of Honduran child blood.

It sounds like, if successful, it will keep you from dying early by preventing you from developing horrific conditions that are common among older people, not that it will keep you young or from inevitably dying with age as everyone eventually does.

I don't really have a cynical hot take. Assuming they can actually get it to work in humans it's wonderful news.

Yeah, now the Japanese can work themselves to death twice as hard!

 

[Ser Prize]

Ok, how do you stop the degradation of DNA? This is just buzzword title that means nothing.

This headline is pretty misleading. These aren't cells that cause aging, these are aged cells. Senescence literally means biologically aged. These cells are basically beyond the divisional limit and divide extremely slowly or don't divide anymore. This won't stop cells from aging, but will clear out aged cells so other cells might divide and not be senescent. It does not prevent cellular aging or divisional limits, this is just a treatment for certain disorders.

At the same time: treating these aged cells is a big step in helping reduce the bad effects of old age.

 

[Snekposter]

The Japanese demand their 3000 year old loli and by god they will get one even if they have to make one

That would imply the Japanese still exist after 3,000 years of no kids.

This headline is pretty misleading. These aren't cells that cause aging, these are aged cells. Senescence literally means biologically aged. These cells are basically beyond the divisional limit and divide extremely slowly or don't divide anymore. This won't stop cells from aging, but will clear out aged cells so other cells might divide and not be senescent. It does not prevent cellular aging or divisional limits, this is just a treatment for certain disorders.

Still important though. Even if its not immortality, a healthier older age is still good. I've heard somewhere that senescent cells not only just sit there, but actively pump out toxins because they're dicks like that, so clearing them out and replacing them with fresher cells is unironically a good thing.