That paper about the vaccine back on the 25th about LINE-1 reverse transcription reminds me of that alleged whistleblower screencap from late 2020:
mRNA Vaccines Actually are "Gene Therapy", Study Shows
igorchudov.substack.com
LINE-1, or Long Interspersed Nuclear Elements, need a little explanation on their own:
en.wikipedia.org
LINE1 (also L1 and LINE-1) are class I
transposable elements in the
DNA of some organisms and belong to the group of
long interspersed nuclear elements (LINEs). L1 comprise approximately 17% of the
human genome.
[1] The majority of L1 in the human genome are inactive; however, about 80-100 have retained the ability to
retrotranspose, with considerable variation between individuals.
[2][3][4] These active L1s can interrupt the genome through insertions, deletions, rearrangements, and
copy number variations (CNV).
[5] L1 activity has contributed to the instability and evolution of genomes, and is tightly regulated in the germline by
DNA methylation,
histone modifications, and
piRNA.
[6] L1s can further impact genome variation by mispairing and
unequal crossing-over during meiosis due to its repetitive DNA sequences.
[5]
L1 gene products are also required by many nonautonomous
Alu and SVA
SINE retrotransposons.
Mutations induced by L1 and its nonautonomous counterparts have been found to cause a variety of heritable and somatic diseases.
[7][8]
Human L1 has been reported to have transferred to the genome of the
gonorrhea bacteria.
[9][10]
Every protein in the body is synthesized like this; DNA is reeled and transcribed into RNA by RNA polymerase:
RNA is translated into a polypeptide by a ribosome:
Polypeptide folds on itself to become a protein:
The protein can then be further processed by enzymes to make any number of other proteins by cutting or attaching bits and pieces here and there. That's how a small number of genes can make tons and tons of different proteins. This is literally what you and I are made out of. Skin, hair, blood, fat, muscle, it all happens like this. It's molecular K'Nex.
DNA is the storage form of a gene. RNA is the active, working form of a gene. The whole point of genes is to act as templates for proteins. When people say "lol, he's got good genes", what they really mean is that someone has good proteins, because those are the actual products of the genes that contribute to the shape and function of the organism.
Reverse transcription is when RNA is turned back into DNA, so it can be used over and over again by RNA polymerase to make more RNA. You guys know why HIV never goes away once someone gets it, right? It's because it uses its own reverse transcriptase to turn its RNA into DNA and insert its genes into the genome of the cells that it infects. The blueprint for the whole virion becomes a permanent fixture inside the infected cell's nucleus called a provirus. The cell will always make HIV virions. Its nuclear DNA, that is, its blueprint collection, has had a file shoved into the cabinet that is now stuck there permanently.
However, reverse transcriptases in retroviruses are not the only way cells can incorporate foreign RNA into their genomes. LINE-1 reverse transcription is an endogenous reverse transcriptase. Our cells just have it naturally and can grab bits of RNA and make them into DNA and incorporate them into their genomes, just like HIV.
In higher eukaryotic genomes, Long Interspersed Nuclear Element 1 (LINE-1) retrotransposons represent a large family of repeated genomic elements. They transpose using a reverse transcriptase (RT), which they encode as part of the ORF2p product. RT inhibition ...
www.ncbi.nlm.nih.gov
Every single motherfucker who said "mRNA vaccines can't turn back into DNA" is a goddamn liar.
archive.ph
