I couldn't sleep for thinking about just how awful this book is. It takes an interesting premise and does absolutely nothing with it. Nobody matters as a person in the story except insofar as they like or dislike trannies.
Let's take the conceit seriously for a second: a plague transforms all men into sex-crazed beasts. Society collapses, but unlike in a typical zombie movie it isn't 99.9% of the population zombified vs a few scattered remnants. In the Manhunt world there are still whole female-only city states. They sound pretty substantial. Even if only 5% of the population is left, that's a lot to work with. After the initial nightmare I think it would be fairly easy to exterminate the roving packs of rape-men. They're basically unthinking animals and they can't reproduce on their own. Their population is going to decline on its own just from natural causes and infighting, and it can't be replenished. Human history is replete with examples of stone age or iron age peoples just wiping out megafauna from entire continents. With modern weaponry, how hard could it be, really?
Then what does society look like? It'd be a nasty place: depleted Children of Men esque world. Cities would be walled, agriculture and industry would happen inside the safe zones. It would look vaguely feudal.
Trannies would be treated as pariahs universally, either barred from entry into civilization or outright hunted down like the rest of the men. But they are so rare to begin with that it barely matters. More interesting is the psychological effect their existence would have on normal society. People would be rightly paranoid, superstitious even. You can easily imagine things descending into witch-trials -- claiming that some woman you don't like is actually a tranny who got really good surgery. People's memories would get distorted, they could easily believe that medical technology used to be better than it actually was, as time goes on and people's memories of the pre-plague world become distorted and mythologized. You could even imagine women getting crazy radicalized and going even after mannish-looking women, or lesbians, or some other group, with wild rumors flying about how even they are somehow susceptible to the plague.
There would be various cults: some believing that this is God's punishment and the human race doesn't deserve to survive. Others, that God is a woman and has smited the inferior sex, with the survivors as the chosen people who will conquer the stars. There would be rumors and hope and fear of a faraway quarantined island with uninfected men.
Speaking of radicalization, when those extermination armies come back home they'll be like Vietnam vets, squared.
Then there's the problem of how to repopulate the Earth. They're on a time limit -- 40-50 years before nobody alive is capable of conceiving children. There are sperm banks in cities -- you can imagine this being a critical resource that rulers would seek to control, like Immortan Joe and the water from Mad Max 4. Imagine the kind of power that would give you -- you get to decide who can breed. And it's not far from there to a despot deciding who must breed. Some societies would end up as "civilized" forms of the very thing they were fighting. And then there's the problem of 50% of fetuses being male.
And oh yeah, every single person is mourning a father, a son, a husband, a brother, many all at once
See how I came up with a plausible world, with interesting, harrowing conflicts that are an organic result of the premise? Notice how none of it dwells on the lurid details? You could write this story and cut to black for any nasty shit that happened. There isn't even a specific political angle, you could write this from a right-wing or left-wing perspective, pro- or anti-feminist, maybe multiple at once.
I probably wouldn't even read the kind of story I've just outlined, but it is scientifically impossible that it wouldn't be better than "Gretchen's" cum-soaked scribblings.