Trooning itself's cause is unknown, there's anecdotal evidence that trutrans types tend to have been born to a mother with hormone imbalances or have them themselves, and it feels like MtFs are almost always retarded regardless of what hormones they take.
Progesterone - horny freaks who take it out on everyone and get mad when they aren't owed sex
Estrogen - MtF troon standard. Either completely normal (very rare) or unhinged and retarded
Testosterone - road to 41%
Ironically, FtMs who take testosterone are rarely as unhinged as MtFs on estrogen, but also are more prone to 41% if prescribed shit like estrogen for birth control, which is typically unneeded because testosterone usually sterilizes them, at least temporarily.