Yes and no. Yes because from what we can see from the leaks, the game at least starts off more intense than the released version (perhaps becoming a bit less serious later on as Duke does shit like riding a donkey). And no because its incomplete and we cant be 100% sure either way.
But the fact of the matter is that 2001 DNF looked far more engaging and feels like overall a much better version of the setup 2011 had. Duke at least comes off as less of a disconnected dick (I still cant forget the "Looks like you are uhh, fucked..." what were they thinking...) and seems to take this more seriously in his own Duke way.
Honestly, that would sound cool. Makes Duke the underdog in a world that enjoyed peace far too much and thus became weaker and ungrateful for Duke's actions, suddenly recontextualizing his victory over the aliens as "senseless slaughter" when they could have perhaps negociated with the aliens. Duke knows that is fucking bullshit but good luck convincing the major younger population of that.
Maybe he is still rich but not popular anymore. I guess we could have a small group of characters that still believe in Duke's actions and maybe they know of a new invasion and are seeking guidance of the only man that was able to stop them last time. It would be a good opportunity to explore Duke's character and the setting that is obviously taking inspiration from our current thankless society that has forgotten its heroes.