The Vtubies aren't going to do anything.
It's like someone's favorite heroin dealer going down in the projects; will their customers be mad? Yeah probably. But ultimately they're going to say "wow this is really stressing me out, who else is holding?" then go and forget about it.
Except Vtubies are even lower function than drug addicts, because at least junkies have to leave their house and deal with other people to get their fix.
The Vtubies are going to cry, then they're going to go watch another anime girl and jerk off, then they're going to go back to their normal state of barely existing and nothing at all will happen, no matter how much the pronouns-in-bio push them around. Because they are pure niggercattle.
Seeing as the trannies only make up less than a fraction of a percentage point of the US population most normies will never run into one. You would have a better chance of winning money in the lottery.
This is why this shit is allowed to continue on without much push back. There isn't enough trannies in real life that normies have to put up with them on a daily basis. This shit will have to just die out like a fad. I have seen other people say this will happen. I believe it will. It will eventually stop. Just like all the cringey shit people do. Look at goths and emos. No one does that shit anymore.
Also because people irl are more worried about things like their neighborhood being burnt down by criminals and looters, inflation, labor issues, etc. over the fact that the mean genderspecials won't let listless shut ins consoom videogame/cartoon/comic/tabletop game in peace.
In the wider context of everything else wrong, trannies are a minor symptom. They're like some kind of sub-predator organism that's really only a threat to children and retards.
If trannies are a rot, well only things that are already dead rot.