A huge chunk of the enemies you face in the game are regular civilians slowly losing control of their own bodies
Reminds me of this manga I started reading recently, called Hour of the Zombie. It's not great, I feel because of its adherence to typical Japanese tropes, highschool setting, and character archetypes, but the premise is really interesting.
One day, suddenly a zombie outbreak starts. All the usual things happen, some people start going feral, the bitten quickly turn, some people get fully eaten, some zombies are killed, etc.
The twist, however, is that as quickly as it started, it passes. All the zombies regain sanity and control, some having sustained injuries and even disfiguration, but otherwise they're all normal. So now the people who did and did not turn have to come to terms with what they did, and what others did to them, during the crisis.
The double twist then is that shortly after, they lose control again and turn back into zombies. It turns out that the infection activates and deactivates in about 30 minute intervals.
So you've got various factions forming, from uninfected who want to save their infected friends, or uninfected who want to restrain or even kill the infected as prevention; and the infected, some of who want to prevent themselves from hurting others, or those who fear they're gonna be dehumanized, rounded up and killed while they're out of control.
And everyone has to make the best use they can of the 30 minute intervals they have to advance their respective agendas, which leads to things like groups alternating between being hunters and preys as the infection turns on and off.
It's a very interesting concept, but as stated, the extremely shallow and stereotypical manga characters ruin the potential.
Still, it has its moments.