Well, the big issue from where I am sitting is that Ontario is overtly antagonizing Manitoba, Saskatchewan and Alberta. Covid, the truckers, carbon taxes, mass immigration etc, they are all grains of sand adding to the pile. Eventually something will break there if the current trajectory continues. And If even one of those provinces breaks and moves towards Union with the USA the other two are sure to almost immediately follow. This would leave British Columbia in a pickle as it would become an exclave attached to the Pacific northwest like a dingleberry, and Ontario would be stuck leading a rump state with Quebec who would probably start agitating to leave again