I wouldn't be shocked if the industry does a soft reset and Sony, Nintendo and Microsoft have a portable arms race. Sony and MS chased the Wii dragon with PSeye and Kinect.
This is exactly what I've been thinking will probably be the next step for them. Sony being one to follow industry trends would probably make the PS6 a hybrid system like the Switch 2, an independent handheld system that can play games natively on the go but with the added "Sony innovation" of a dock possessing an additional, more powerful GPU core to boost performance (similarly as some handheld PCs are able to connect via USB-C Thunderbolt to external GPUs) so games can run at higher settings than in handheld mode ( and a way to justify a higher sticker price ).
Furthermore, we really have to come to terms with the reality that physical media is no longer a concept desired by the corporate powers that be, that ship has sailed.
Even Nintendo has connivingly introduced those shitty key-cards which are glorified download codes attached to a piece of plastic just so they can have complete control to the way their costumers can have access to their games. This is going to be par for the course in the console space moving forward. Blu-ray is the last optical disc that'll be available to consumers, after that everything related to keeping data will be done on solid state storage inside the console. Any game data that can be kept as a local, external backup will be done "unofficially" by the end user against TOS of the console manufacturer.
I mean, I'm quite pessimistic about GTA6 and wouldn't pay money for it even if it NEVER got cracked, but the reality is it could be a while.
I'm pessimistic as well on two different counts:
1. The game will have very aggressive DRM and mandatory online connection that is checking constantly for the validity of your copy. Not saying that it will be impossible to crack but probably difficult enough to make it a very prolonged process, which leads to ...
2. People won't wait, consumers gotta consume and this game will break sales records like nothing we have even seen before. Rockstar knows this and because of this certainty the base game is probably going to be $90 and $100 for Early Access and with whatever Special or Collector's Edition they'll cook up the sky is the limit when it comes to pricing.
No matter how you dice it, shit is grim.