Wuhan Coronavirus - COVID-19 Analysis & Summary - This is not just fucking pneumonia. It is everything but the kitchen sink. Lungs, heart, kidneys, liver, brain, blood vessels, testes. It affects them all.

[Sped Xing]

Took a quick trip to Google and here's what I found dated 2015:
View attachment 1230151

So maybe he's not lying about his income. Hm.

So quikmaffs, 47 an hour 40 hours a week is 92k a year. If his dad makes 120k a year that pretty much guarantees he's a captain and pulling long shifts. Has this been covered? We need a consolidated OP.

But point being, Davy Jones, maybe it's best you not severely embarass your big shot padre upon whom you rely for your five bottle a week Jack habit.


EDIT: More maths fun. 140 dollars on booze a week? At $53.97 for 1.75 L Gentleman Jack (because we have taste,) that's 4.54 L per week, or 0.649L per day. With a generous 40mL per shot, that's. . . holy Christ, kid, 16 drinks every day? How do you stay lucid enough to worry about Covid? Your liver is going to fail long before your lungs do!


EDIT 2: Not everyone here drinks, so for perspective, unless he's drinking very fancy stuff, and I used a premium brand to calculate, he's essentially drinking one drink every waking hour, which means he is *never* sober. That includes work hours. Even if he slams 16 shots back the second he gets off work, mathematically that means he's still far over the legal limit while on the job, every single day.

Or maybe he's just lying. I hope he's just lying. Which is it, David? If you're drunk on the way to work, don't we have an obligation to report such reckless behavior? Or are you a stupid, fat, lying autist who can't even hack being an adult?

 

[tuscangarder]

Mysterious Heart Damage, Not Just Lung Troubles, Befalling COVID-19 Patients

Most of the attention in the COVID-19 pandemic has been on how the virus affects the lungs. But evidence shows that up to 1 in 5 hospitalized patients have signs of heart damage and many are dying …

khn.org

 

[evrae]

Mysterious Heart Damage, Not Just Lung Troubles, Befalling COVID-19 Patients

Most of the attention in the COVID-19 pandemic has been on how the virus affects the lungs. But evidence shows that up to 1 in 5 hospitalized patients have signs of heart damage and many are dying …

khn.org

I'd personally want to see papers on this, but since its known that CoV-2 is capable of entering various cells, but failing to replicate in them, it seems more likely this may be a result of major inflammation and cytokine storms that are previously described.
If that's the case, it'd be good to use drugs to dampen the inflammatory response in combination with any sort of antivirals used, in which reports mentioned earlier have stated that there are currently trials in place to deal with this. This is also compounded by the fact that elevated levels of IL-6, a pro-inflammatory cytokine, is indicative of poor prognostics.

https://www.sciencedirect.com/science/article/pii/S104366182030743X?via=ihub

There's this report that I've found in that previously posted Nature article, it's talking about Tradition Chinese Medicine though so I'm not particularly sure on its legitimacy (though there are other papers mentioning anti-inflammatory effects in influenza and COPD too). There are also trials described using tocilizumab and the potential for small-molecule inhibitors too so it looks like there is progress being made in this regard, hopefully papers will get published or put in pre-print with these treatments soon.

 

[tuscangarder]

I'd personally want to see papers on this, but since its known that CoV-2 is capable of entering various cells, but failing to replicate in them, it seems more likely this may be a result of major inflammation and cytokine storms that are previously described.
If that's the case, it'd be good to use drugs to dampen the inflammatory response in combination with any sort of antivirals used, in which reports mentioned earlier have stated that there are currently trials in place to deal with this. This is also compounded by the fact that elevated levels of IL-6, a pro-inflammatory cytokine, is indicative of poor prognostics.

https://www.sciencedirect.com/science/article/pii/S104366182030743X?via=ihub

There's this report that I've found in that previously posted Nature article, it's talking about Tradition Chinese Medicine though so I'm not particularly sure on its legitimacy (though there are other papers mentioning anti-inflammatory effects in influenza and COPD too). There are also trials described using tocilizumab and the potential for small-molecule inhibitors too so it looks like there is progress being made in this regard, hopefully papers will get published or put in pre-print with these treatments soon.

 

[evrae]

-pre-print paper link-

Thanks for that.
It looks like the myocarditis described isn't unique to CoV-2, being previously described in MERS-CoV (46). There's also descriptions of autopsy findings of inflammatory mononuclear infiltrate in myocardial tissue (26, 47, 48) (this is basically cells of the immune system infiltrating heart tissue). Suggesting that inflammation is present in this tissue, which is likely the responsible cause for the damage.
There's also descriptions of arrythmias in CoV-2 cases, being attributed to things such as hypoxia (lung damage of course results in worse blood oxygenation, obviously), and inflammatory stress (something that is being found often).

It reads to me like the infiltration of cells by CoV-2 is triggering inflammation and immune responses that are compounding problems caused by the general respiratory system damage (hypoxia and such). There also suggestions in this paper that patients with CVD and hypertension have higher expression of ACE2 which consequently increases susceptibility to CoV-2 (5).

I think we're on the right track by looking at keeping the immune system/inflammation under control during infection, as it seems like the hyperactivity of it during infection might be what's causing the most damage.

 

[SIGSEGV]

Secondly, Oilers do more than just "lubricate boats". We also do a great deal of maintenance work, including fucking undoing head bolts and pulling power packs, fixing plumbing, doing hull restoration work (i.e. needle gunning and painting and shit), replacing fluorescent lamp ballasts, et cetera, et cetera.

I have personally pulled used diapers and tampons and shit out of a clogged sewage pump check valve with a pair of pliers because people are fucking disgusting and they think a toilet is a trash can. My coworkers are all fucking criminally exceptional. One guy couldn't figure out how to get music off a thumb drive, and I actually had to show him how. Another one recently got back from a vacation to Mumbai. Why would you go to Mumbai when you could go literally anywhere else?

You're a fucking janitor, faggot.

Took a quick trip to Google and here's what I found dated 2015:
View attachment 1230151

So maybe he's not lying about his income. Hm.

@Drain Todger is anything but ordinary, he's exceptional.

 

[ADHD]

EDIT 2: Not everyone here drinks, so for perspective, unless he's drinking very fancy stuff, and I used a premium brand to calculate, he's essentially drinking one drink every waking hour, which means he is *never* sober. That includes work hours. Even if he slams 16 shots back the second he gets off work, mathematically that means he's still far over the legal limit while on the job, every single day.

David being drunk all the time would actually explain a lot.

 

[Spooky Bones]

imbecilic

Did you pick up this word from @Zhan-Tiri13?

No matter, I ship the two of you anyway.

 

[Sped Xing]

Is he spending all his money to acquire child porn? We already know he's such a pedo that porn of childlike pastel ponies from a kid show isn't enough; he needs porn of childlike pastel ponies which are overtly in kid show canon grade schoolers.

I'm just trying to figure out his budget. Maybe we can help.

 

[MetalParakeet]

David being drunk all the time would actually explain a lot.

Remember when he also claimed to only sleep a few hours a night? A massive ton of alcohol every day plus three hours sleep on the reg?

That would explain a whole ton. He's not autistic, he's just suffering an alcoholic psychosis!

 

[So-and-so]

Just finished reading the thread, and I have to say, it was a real page turner. I genuinely couldn’t put it down. I have some questions for @Drain Todger, if he would be so kind to oblige:

1. Are you under the impression that the people in this thread, or on this forum in general, are not taking the crouching tiger, hidden sniffle seriously enough? You go on and on about how dangerous or unprecedented this is, as if the people that you’re preaching to haven’t told you repeatedly that they’re taking the situation seriously, and are taking precautions.

2. I’ve watched some of the videos that you’ve posted here, and I see you recording outside, without wearing proper PPE. Are these being filmed at your house, or somewhere else? If you’re not in quarantine at home, why aren’t you wearing proper PPE?

3. Have you started a diet and workout regimen to reduce your weight, and thus the stress to your immune system? You’re quite clearly overweight, and your friends and family can’t benefit from your insight if you aren’t well enough to share it with them.

4. What do you do in your free time when not obsessing over this?

5. Have you been diagnosed with anything other than autism? What is your IQ?

 

[SIGSEGV]

4. What do you do in your free time when not obsessing over this?

You know damn well what he does in his free time.

 

[AlexJonesGotMePregnant]

i was not expecting that he'd be a raging alcoholic but it fits his sporadic posting and inability to say anything even remotely coherent. it's taken him months to slap together a shitty "paper" that reads like some second year bio student a la Zinnia Jones.

- Fat
- Tranny
- No friends
- Brony
- Alcoholic
- Obese
- Ugly
- Autistic
- Banned from everywhere except KF
- Clout chasing
- Low IQ
- Doomer

I hope he doesn't ever leave KF, i love this thread.

 

[So-and-so]

You know damn well what he does in his free time.

Well, yes we all know about that, but someone earlier asked if he was into stuff like factorio, since that would definitely be a good fit for him. I just get the impression that he might have other projects that he uses to occupy himself, and I'm very interested to hear about them.

 

[Sped Xing]

In David's defense, he may not be lying about how much he drinks. He has stated that he fantasizes about being the bottom in sex.

It's hard to "*fuck* the pony" when your hourly whiskey dose has rendered you impotent.

 

[LemmeSee]

I don't think anyone has mentioned snoop snoo in this thread yet. Someone ran it on the THASF account a year ago. The analysis on what time he posts his comments are fascinating to look at.

http://archive.is/iXxIr

 

[So-and-so]

Oh, look, he's an anarchist. See this is what I'm talking about. I'd love to hear about his political theory and what models he has for a successful anarchist society. I bet he's done tons of reading on the subject. He doesn't seem like the type to come to such a decision lightly.

 

[Mr. Skeltal]

Yeah, it's not unique. It's also a property of HIV, Ebola, and Epstein-Barr.
Not good. Not good at all.

Allow me to introduce you to a stunning new concept that you may not have been exposed to: convergent evolution. Environmental pressures will select for specific behaviors, morphology, and diet given certain conditions. In animals, the convergence on a similar form, behavioral pattern, and diet of unrelated groups can be seen with the old grouping of anteaters with aardvarks and pangolins in the now defunct order Edentata due to their collective lack of fully developed teeth, insectivorous diet, and large digging forelimbs.

Presuming that viruses are quasi-living entities, they too would be subject to the whim of environmental factors in their fate. The polyphyletic nature of the group you listed - a retrovirus, a filovirus, and a herpesvirus that all display the ability to infect immune cells - supports a convergent evolution origin hypothesis for this trait, as it seems to confer some benefit in their ability to persist and propagate within a host. In lay speak, it's evolutionary coincidence. To say that SARS-2-CoV is in someway related to them beyond the broad category of virus because of this ability is not a tenable position.

By the by, viral infectivity in immune cells is what causes the dreaded cytokine storm, which something as mundane as H1N1 influenza can and will do.

I'm no biologist nor a virologist, but my field - geology - is an interdisciplinary field; you learn the basics of the other fields. The core tenents of science are applicable to each and every science.

EDIT: This thread in a nutshell:

 

[evrae]

Allow me to introduce you to a stunning new concept that you may not have been exposed to: convergent evolution. Environmental pressures will select for specific behaviors, morphology, and diet given certain conditions. In animals, the convergence on a similar form, behavioral pattern, and diet of unrelated groups can be seen with the old grouping of anteaters with aardvarks and pangolins in the now defunct order Edentata due to their collective lack of fully developed teeth, insectivorous diet, and large digging forelimbs.

Presuming that viruses are quasi-living entities, they too would be subject to the whim of environmental factors in their fate. The polyphyletic nature of the group you listed - a retrovirus, a filovirus, and a herpesvirus that all display the ability to infect immune cells - supports a convergent evolution origin hypothesis for this trait, as it seems to confer some benefit in their ability to persist and propagate within a host. In lay speak, it's evolutionary coincidence. To say that SARS-2-CoV is in someway related to them beyond the broad category of virus because of this ability is not a tenable position.

By the by, viral infectivity in immune cells is what causes the dreaded cytokine storm, which something as mundane as H1N1 influenza can and will do.

I'm no biologist nor a virologist, but my field - geology - is an interdisciplinary field; you learn the basics of the other fields. The core tenents of science are applicable to each and every science.

EDIT: This thread in a nutshell:
View attachment 1230748

Good point! That's a post I didn't notice.
There are some traits or behaviors that develop in evolution very often generally because they're a net gain regardless.
In a pathogens case, having some form of dealing with the immune system in some way is pretty critical to be successful and propagate further within the host.
This issue can be approached in different ways, for some, you can simply survive within phagosomes by some means or another, avoiding immunosurveillance by preventing digestion and subsequent antigen presentation. Some go for a more direct approach and just outright infect cells of the immune system.
As you've said yourself, this is something influenza can pull off, and so can MERS-CoV, it's not something unusual in this case from the sounds of it.
Avoiding detection is a critical thing in just about any disease, even cancer conducts this by various different means.

This is a hugely complex field though, and I'm largely unfamiliar with infection methods from diseases that aren't the ones I research so I won't regard myself as an expert in things other than the stuff that I actually do work on.

 

[AbraCadaver]

So quikmaffs, 47 an hour 40 hours a week is 92k a year. If his dad makes 120k a year that pretty much guarantees he's a captain and pulling long shifts. Has this been covered? We need a consolidated OP.

But point being, Davy Jones, maybe it's best you not severely embarass your big shot padre upon whom you rely for your five bottle a week Jack habit.

He’s already a fat ugly autist pretending to be a woman because real women won’t touch him and he posts cartoon ponywanking fantasies online. His dad has plenty to be embarrassed about already.