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kiwifarms.net
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- Oct 5, 2018
Nature selects mutations for fitness. A better-fitted virus would be more virulent, less deadly. But herd immunity doesn't give the virus any opportunity to reproduce, so mutations will be brought to a stop.I think the big concern about taking a complete herd immunity approach is the virus mutating
Such a guarantee is impossible for any virus, but vaccine research targets the spike protein, and if the spike protein mutates, the virus can't enter cells anyway. It would have to undergo some very specific adaptations to make the spike invisible to the immune system while maintaining its function. I might start listening to Michael Behe if that happened.- we're still adding new symptoms to the list, and there's no guarantee that a vaccine will do any good if the virus adapts to it.

Study of antibody response to SARS-CoV-2
Summary of article about identification of specific areas on spike protein of SARS-CoV-2 that appear to trigger strong protective antibody responses in rabbits
The same argument has been made about influenza, filoviruses, etc. Anything could mutate into anything else. The Shredder could pour mutagen onto ebolavirus and cross it with a rhinoceros. If we spent years being cautious about every possible mutation, we would've shut everything down 100 years ago and never reemerged from our Spanish Flu shelters.If the rumors about Brazil's native bat population inducing more frequent mutation are true then it's not so much what the virus is capable of, moreso what it could be capable of. I'm no expert on how viruses mutate so I have no idea how likely a nightmare scenario is, but there are arguments to be made(and being made) for continuing a cautious approach for months, if not years.