Wuhan Coronavirus: Megathread - Got too big

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I keep hearing the rumbles of fear about Spring Break and crowded beaches, so I looked for some livestreams to see what's going on.

Fort Lauderdale seems... sad?
Ft Lauderdale has tried really, really hard to stop the raving masses of spring breakers from destroying its beaches every year. If you look at the streams from Miami Beach this weekend where there was rambunctiousness bordering on violence, it's clearly a lot of young adult townies who came in and not the media created images of white fraternity brothers that fly back to their colleges while bringing the coof.

No city wants this type of thing to happen because it causes more problems than the influx of money brings. Just look at the history of Freaknik, the black Atlanta party weekend in April that got shut down when people started getting shot, stabbed, and robbed all the time.

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If Canada wanted vaccines they shouldn't be such pussies exulting in their mediocrity. They sold off all their industry to Asia, now they have to live with those consequences. Mexico is a third world country, so that's more understandable. They'll get their vaccines once America is good, but they ought to pay for them.
 
I'm okay with this because krispy kreme glazed donuts are disgusting and preferring them over any other donut in existence is a sign of being sub-human.
Honestly the only reason I go there is because Oregon doesn't have a Dunkin' or a Tim Hortons. Kripsy Kreme has some decent cake donuts and custard filled, but their glazed shit gives me diabetes.
 
Movie theather over here went out of business despite being open for months and had huge glaring signs signalling that its open. The next movie theater is like a hour out of town. Then a huge portion of a mall followed after.
I don't like this at all, this is going to be very likely a ruined town if/when this ends.
 
If those vaccine cards ever become a thing a Taobao china man will be your best friend :feels:
Cards are a thing but the policy is being mulled for few weeks untill the requirment get legal power to detain or restrict people who have not gotten the shot .
 
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Ugh. Disgusting. Everyone knows lemon curd donuts are the food of the master race.

"Congrats on your coof jab, citizen unit! Now indulge your healthy at any size lifestyle and pwn the anti vaxxxxxxxxxxxxers by consooming our sugar bread!"
They're using the Planet Fatness model of encouraging their clientele to keep using their service by giving them free unhealthy food, like Pizza Monday and Bagel Tuesday.
 
Well cancer isn't a virus (or bacteria, or archea, or fungi, or parasite, or biotic toxin...); so what would the vaccine be?
A vaccine against your own body?
No, but basically the mRNA stuff trains the body to recognize a certain protein which could be a really useful tool. All types of cells/microscopic life express all sorts of unique molecules on the outsides of them. I think cancer cells are a little fucky in what they express on their exterior cell wall, so this is probably what they could teach the immune system to target, the thing the sick cells are expressing and not the healthy (sort of like the spikes on covid). Your body plays cat and mouse with cancer cells, the cancer tries to evade the killer T-cells, but if you could give the T-cells a leg up, point them at the right targets, they they could do serious damage to cancer. This all varies depending on the type of cancer etc. Honestly if this stuff turns out to be ok (after it's studied properly and not rushed) it could mean a lot for cancer patients. It's like a targeting laser for whatever the makers of the mRNA want to target, granted the body is very complex, and there is more to it than this, but this is just my non-expert understanding.
 
No, but basically the mRNA stuff trains the body to recognize a certain protein which could be a really useful tool. All types of cells/microscopic life express all sorts of unique molecules on the outsides of them. I think cancer cells are a little fucky in what they express on their exterior cell wall, so this is probably what they could teach the immune system to target, the thing the sick cells are expressing and not the healthy (sort of like the spikes on covid). Your body plays cat and mouse with cancer cells, the cancer tries to evade the killer T-cells, but if you could give the T-cells a leg up, point them at the right targets, they they could do serious damage to cancer. This all varies depending on the type of cancer etc. Honestly if this stuff turns out to be ok (after it's studied properly and not rushed) it could mean a lot for cancer patients. It's like a targeting laser for whatever the makers of the mRNA want to target, granted the body is very complex, and there is more to it than this, but this is just my non-expert understanding.
Except there is more money in treatment than cure.
 
Except there is more money in treatment than cure.
It's definitely an incredibly negative way of looking at it, and with our (USA) Healthcare system it's easy to look at it that way. Although just giving a cursory glance at what a cancer vaccine entails, it certainly doesn't sound any cheaper.

From Moderna's site: https://www.modernatx.com/pipeline/...sonalized-cancer-vaccines-and-immuno-oncology
Moderna is creating individualized, mRNA-based personalized cancer vaccines to deliver one custom-tailored medicine for one patient at a time. Through next-generation sequencing, we identify mutations found on a patient’s cancer cells, called neoepitopes. Neoepitopes can help the immune system distinguish cancer cells from normal cells. Using algorithms developed by our in-house bioinformatics team, we predict 20 neoepitopes present on the patient’s cancer that should elicit the strongest immune response, based on unique characteristics of the patient’s immune system and the cancer's particular mutations. We then create a vaccine that encodes for each of these mutations and load them onto a single mRNA molecule.

A customized vaccine, on a per patient basis? I mean, that doesn't sound very cheap to me. I don't think it's a "one size fit's all" type deal, like with a flu shot, cancers sound like they have lots of variability.
 
Except there is more money in treatment than cure.
This is a commonly repeated misconception and it's not true.

There is BIG money to be made in drug discovery, and a working cure for even 1/2 the known human cancers would be the holy grail of drug discovery, and whichever scientist managed to get their name as first author on the efficacy paper would probably go down in history alongside Alexander Fleming and Walter Reed (*or some gender-fluid POC who worked as a lab tech would*).

Furthermore, the amount of money thrown at cancer research itself is proof that this is not the case.
My undergrad advisor straight up told our lab that no matter what our hypothetical future research was about, that if we could find even the most tenuous second-hand link to cancer research, then we were golden.
 
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