In previous clinical trials since the 1960’s [8] attempts to vaccinate against RSV, [9] Dengue, [10] SARS and MERS, the studies each failed during the animal phase. Cats, ferrets, monkeys, and rabbits each and every time experienced Antibody Dependent Enhancement (ADE), also known as pathogenic priming or a cytokine storm. This occurs when the immune system creates an uncontrolled and overwhelming inflammatory response upon being confronted with the pathogen in the real world, and the outcome, tragically, is death. The same immune system overreaction took place in a number of infants in clinical trials who received an attempted RSV shot, as well as some six hundred Filipino children who died following early vaccination against Dengue [11] and it remains a viable concern today. [12]
Autoimmune disease occurs when the body's immune system can't tell the difference between its own cells and foreign cells, and causes the body to attack its normal cells. [13] It has been suggested that "molecular mimicry" may contribute to this problem, with antibodies to SARS-CoV-2 cross-reacting with structurally similar host protein sequences and raising an acute autoimmune response against them. [14]
Scientists have determined that the same spike protein found in SARS viruses are also responsible for the development of the placenta in mammals, including humans, and is therefore an essential prerequisite for a successful pregnancy. If a woman’s body is primed to attack these protein spikes, the immune system may prevent a placenta from being formed, which would render that woman infertile. [15]
