No ovaries required: viable eggs grown in a dish

No ovaries needed: viable eggs grown from mouse stem cells

Growing eggs from basically nothing!!!

cosmosmagazine.com

Scientists have successfully coaxed mouse stem cells to develop into functional eggs in a dish – that then grew into baby mice, according to a study published in Developmental Biology.

This has wide implications for assisted reproductive technologies in the future, because it may provide an alternative to egg donors.

A team of researchers, led by Takashi Yoshino of Kyushu University, Japan, developed culture conditions in a petri dish that imitated ovarian follicles to recreate the process that stem cells normally take to turn into eggs, which resulted in viable eggs. They called the lab-grown cells ‘reconstituted Ovarioids’ (rOvarioids).

Pluripotent stem cells are immature but have the potential to become almost any type of cell under the right conditions. In the ovary, these cells can become oocytes, which eventually turn in to eggs.

Normally, oocytes are encapsulated by ovarian cells in a fluid-filled follicle structure that help the oocyte undergo a round of meiosis (a type of cell division) and become an ovum (an egg that can be fertilised).

Previously, it was hard to grow the oocytes and ova in a petri dish because the ovarian follicles are essential in the process, so the team developed a culture as an “incubator” for the eggs to grow in, outside of the ovary.

The team took stem cells from mature female mice and placed them in the culture. This simulated the normal ovary environment so effectively that the stem cells developed into functional oocytes –rOvarioids – that could later be fertilised via in vitro fertilisation (IVF) and implanted into mice wombs.

Incredibly, 5.2% of the embryos derived from rOvarioids grew into babies after implantation, and all of the babies born via the method grew to adulthood.

This is comparable to the effectiveness of IVF-derived embryo transfer success in people over 43 years of age, but there is no restriction on the amount of eggs available, because lots of rOvarioids can be made.

“This technical breakthrough holds enormous potential for (reproductive) cell research,” says Lin Yang of the Genome Institute of Singapore.

Ying explains that this allows for high-yield IVF entirely without eggs or genetic manipulation.

Reconstitution of follicle structures, including oocytes, entirely from mouse pluripotent stem cells. Illustrations on the left show a schematic overview of reconstitution of both the ovarian filament cells (FOSLCs) and stem cell-derived eggs (PGCLCs) from mouse stem cells. Oocytes in the reconstituted environment gave rise to offspring after fertilization. The right image represents fully grown cumulus-oocyte complexes derived from FOSLCs (red) and PGCLCs (blue). Credit: Yoshino et al.

 

[Joe Swanson]

We need our horrifying sticker back

 

[frozenrunner]

You know what this means! Western women congratulating themselves for focusing on career and not having kids until they're in their 40s.

Hell, maybe the ones rich enough to afford this will pay someone else to carry the baby to term, too.

 

[Corpun]

Stop. Playing. God.

I'm fuckign serious. Roasties and career women will probably pay out the assload for their tard baby with this surgery, though I suspect trannies might be the intended use in the end, so we gotta cater to them.

 

[Blobby's Murder Knife]

Curious why the failure rate was still so high, comparable to still using eggs past their expiration dates.

Stop. Playing. God.

I'm fuckign serious. Roasties and career women will probably pay out the assload for their tard baby with this surgery, though I suspect trannies might be the intended use in the end, so we gotta cater to them.

Well, honestly my first thought when I read the title was of troons trying to use this as another way they could be True and Honest women, not of career women.

 

[Maurice Caine]

Curious why the failure rate was still so high, comparable to still using eggs past their expiration dates.

Well, honestly my first thought when I read the title was of troons trying to use this as another way they could be True and Honest women, not of career women.

I'm thinking, the japs are certainly going to use this to mitigate their population deficit

 

[Corpun]

I'm thinking, the japs are certainly going to use this to mitigate their population deficit

The Japs just need to crackdown on their NEET population and enforce traditional Imperial Era values. They will need it with the rise of Beijing in Asia.

 

[Maurice Caine]

The Japs just need to crackdown on their NEET population and enforce traditional Imperial Era values. They will need it with the rise of Beijing in Asia.

That's not gonna fly these days, man. Beijing's a paper tiger anyways.

 

[🌐🌐🌐]

I'm thinking, the japs are certainly going to use this to mitigate their population deficit

I think that their problems are more cultural and economical in nature, people just don't want to be parents or cannot afford it.

 

[MarvinTheParanoidAndroid]

Okay women, now you may panic about being replaced.

 

[whatever I feel like]

I don't think I like this.

 

[fine tooth comb]

finally i will have a daughter that will cook, clean, and i can rape everyday, the future is looking bright, people

 

[MarvinTheParanoidAndroid]

I'm fuckign serious.

"r ou guvking happy nao?!"

 

[murdered meat bag]

aborting children to create children. what a world.

 

[Queen Elizabeth II]

Men and Wohymxn are better at being women than women are at being women.

Lmao

 

[Queen Elizabeth II]

That's not gonna fly these days, man. Beijing's a paper tiger anyways.

How many years have we been calling China a bubble now?

They're setting up ports and roadways that will ensure their dominance for centuries to come; do they have to see the rise of their God Emperor and declare the eternal mandate of heaven or something before we might consider them an economic threat?

 

[MarvinTheParanoidAndroid]

Men and Wohymxn are better at being women than women are at being women.

Lmao

As much as I hate trannies, this obnoxious push for traditionalism in gender roles makes me want to embrace whatever Frankenstein shit science has to offer, just to spite everyone else.

The idea that women should fit into specific archetypes is no different in principle than the shit John Money pushed, that you can just change the fundamental attributes of a person & make them into something they're not against their will.

How many years have we been calling China a bubble now?

They literally have people laying down on the ground as a form of protest at how shitty their lives are because they can't protest any other way. China is on the verge of eating itself, and spends more on internal surveillance than they do on military. There's a reason why they're getting aggressive toward other countries, and it's because they know this long shot is their last one.

 

[Dona Morte]

I will enjoy the tantrums of women who will not be able to find a man because guys who want a legacy will just do this.

 

[Fomo Hoire]

Imagine using aborted babies to make these eggs. That would be some evil villain movie shit right there, effectively shortening the period between generations from two decades to less than a year. Do this for a few years and you'll be generations ahead of the human race.

Eventually you let these develop and it turns out they have 2 foreheads and 7 chins and faces only a mother could love. But they have no mothers because you aborted them to turn them into eggs. Loveless abominations.

And that's how you get the super soldier army that will destroy us all.

 

[Johan Schmidt]

IVF is already Dysgenic as fuck. This will make it more so.