Brianna Wu / John Walker Flynt - "Biggest Victim of Gamergate," Failed Game Developer, Failed Congressional Candidate

Wouldn't the rarity of the disease mean it's not cost effective to invest time and money into a cure?

Most of these rare genetic diseases have things in common, so research on one is often useful for all of them. For instance, Huntington's is a result of a stutter in DNA transcription where CAG repeats over and over again, resulting in a protein that has a long chain of gibberish in it, which eventually builds up and causes brain damage and kills you. This sequence normally repeats, but the more you have, the more you're likely to get it, and the sooner it will kill you.

There are a number of genetic disorders like this, where there's a normal range of some sequence repeating, and you're okay with a certain number, but where if that repetition goes on and on, you get some weird fucked up protein building up over the course of your life until you die.

The reason the government is the only thing that can really effectively do research in this, though, is you can't patent general knowledge. So figuring out things about this general class of disorders can't be profitable. You can't make much money patenting something that benefits 300 people, even if the research you did for it benefits hundreds of thousands of people once you add in everyone with similar disorders.

This is why entities like the NIH fund basic research in these areas. With that done, though, our heroic pharmaceutical companies can step in and use that research to make drugs for the myriad of disorders that the basic research helps.

The problem with private industry doing this itself is that you can spend an enormous amount of money doing basic research that benefits everybody, but there's no way to capture the profits yourself. So it just doesn't get done without public funding. Once that funding is done, though, going the final step and coming up with drugs and treatments becomes profitable, since you can easily patent the drug specifically for Huntington's or the other diseases with the same features.

This is pretty academic, since John would never be put on any committee with anything to do with this even if he unseated an unbeatable incumbent.
 
I'm still not buying it. When in the John Flynt timeline did this bullshit happen? Before or after he was "homeless?" Was this during the ten years of failing to get a degree at a number of universities? Or was it after he was an "investigative journalist?" Or maybe it's some time before he became an "engineer."

John has never even told this lie before, so I'm really suspicious. How could he have failed to mention this all this time when he does nothing but virtue-signal all day long?

I should have made it clear that I also don't think Flybt/Wu ever went on a mission trip to Central America. If he had, there would have been hundreds of tweets beginning with "When I was in Central America." (But don't worry; those tweets are inevitable now that this new lie has been worked into the timeline.)

I think that, like everything in Flynt/Wu"s autobiography, this is something he fantasized about but never did. ("Alone at last in our jungle tent, I slowly waddled toward the cot upon which Billy Bob Calhoun's sleeping body lay. The flooring creaked alarmingly under my 340 pounds of loathsome fat, but his muscular young body did not stir as I moved closer, my bloated, sweating hand outstretched . . .")
 
I should have made it clear that I also don't think Flybt/Wu ever went on a mission trip to Central America. If he had, there would have been hundreds of tweets beginning with "When I was in Central America." (But don't worry; those tweets are inevitable now that this new lie has been worked into the timeline.)

I think that, like everything in Flynt/Wu"s autobiography, this is something he fantasized about but never did. ("Alone at last in our jungle tent, I slowly waddled toward the cot upon which Billy Bob Calhoun's sleeping body lay. The flooring creaked alarmingly under my 340 pounds of loathsome fat, but his muscular young body did not stir as I moved closer, my bloated, sweating hand outstretched . . .")

Never write Brianna Wu fanfic again.
 
Anyone else notice how Wu's Tweeting rate has dropped over the past couple of days from many dozens to only a couple dozen exceptional thoughts?

Quiz - What is Brianna doing with her time?

  • Actually restoring the Audi TT and totally not making Frank and mechanics do the cleanup while she sits back to enjoy another Potbelly sandwich
  • Playing vidya and lamenting being 40
  • Accepting money from places/spending money on companies she has promised to boycott and trying to keep it a secret like she tried to do with her week in NC
  • Godzilla campaign ad
  • Huffing paint
 
Anyone else notice how Wu's Tweeting rate has dropped over the past couple of days from many dozens to only a couple dozen exceptional thoughts?

Quiz - What is Brianna doing with her time?

  • Actually restoring the Audi TT and totally not making Frank and mechanics do the cleanup while she sits back to enjoy another Potbelly sandwich
  • Playing vidya and lamenting being 40
  • Accepting money from places/spending money on companies she has promised to boycott and trying to keep it a secret like she tried to do with her week in NC
  • Godzilla campaign ad
  • Huffing paint

Mid-life crisis
 
Anyone else notice how Wu's Tweeting rate has dropped over the past couple of days from many dozens to only a couple dozen exceptional thoughts?

Quiz - What is Brianna doing with her time?

  • Actually restoring the Audi TT and totally not making Frank and mechanics do the cleanup while she sits back to enjoy another Potbelly sandwich
  • Playing vidya and lamenting being 40
  • Accepting money from places/spending money on companies she has promised to boycott and trying to keep it a secret like she tried to do with her week in NC
  • Godzilla campaign ad
  • Huffing paint
Ambien binge in DC. Throwback Thursday ended up being a multi-day affair.
 
Huntingdon's Disease is genetic, dumbarse. You'd need to resort to extensive genetic testing and a pinch of eugenics to solve it.

Tay-Sachs Disease has been virtually eradicated in Israel by simply making sure people with the recessive genes for it don't match them up with others. This is probably the first case of eradicating an inheritable disease.

Eugenics has an undeserved bad name.
 
This week on Brianna's Hot Takes....

mass effect is shit.png


Previously on Brianna's Hot Takes....

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Added bonus:

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Hrm, who could possibly be debased enough to purchase such filth?
Oh. Right.

perverted garbage gamer.png
 
This week on Brianna's Hot Takes....

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Previously on Brianna's Hot Takes....

View attachment 244683

Added bonus:

View attachment 244686

Hrm, who could possibly be debased enough to purchase such filth?
Oh. Right.

View attachment 244684
We need a GGer to challenge John in D8. I need to see The People's Gaming Debate.

"Ms. Wu, on such and such date you said that Game X was, quote, "worthless oversexualizing trash made by a despicably culturally appropriating alt-right misogynist," yet one can clearly see by reviewing your Steam achievement history..."
 
We need a GGer to challenge John in D8. I need to see The People's Gaming Debate.

"Ms. Wu, on such and such date you said that Game X was, quote, "worthless oversexualizing trash made by a despicably culturally appropriating alt-right misogynist," yet one can clearly see by reviewing your Steam achievement history..."
"Don't mansplain my purchases and my Twitter feed to me!"
*Snarl*
 
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