Can someone TELL me what this means? - What's a get up and go and how does it got up and went?

[Dr. Arinsu]

 

[PonderosaPete]

Means you've become a bottom instead of a top

 

[Lou Bega]

It means your ability to get off your lazy ass and be productive has gone away, possibly caused by you gooning 13 hours a day to hentai.