Chinese scientists create robot with brain made from human stem cells - Researchers have developed brain-on-chip technology to train the robot to perform tasks such as gripping objects



Chinese scientists create robot with brain made from human stem cells

Researchers have developed brain-on-chip technology to train the robot to perform tasks such as gripping objects

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Chinese scientists have developed a robot with a lab-grown artificial brain that can be taught to perform various tasks.

The brain-on-chip technology developed by researchers at Tianjin University and the Southern University of Science and Technology combines a brain organoid – a tissue derived from human stem cells – with a neural interface chip to power the robot and teach it to avoid obstacles and grip objects.

The technology is an emerging branch of brain-computer interfaces (BCI), which aims to combine the brain’s electrical signals with external computing power and which China has made a priority.

It is “the world’s first open-source brain-on-chip intelligent complex information interaction system” and could lead to the development of brain-like computing, according to Tianjin University.

“[This] is a technology that uses an in-vitro cultured ‘brain’ – such as brain organoids – coupled with an electrode chip to form a brain-on-chip,” which encodes and decodes stimulation feedback, Ming Dong, vice-president of Tianjin University, told state-owned Science and Technology Daily on Tuesday.

BCI technology has gained widespread attention due to the Elon Musk-backed Neuralink, an implantable interface designed to let patients control devices with only their thoughts.

Tianjin University now says its research could lead to the development of hybrid human-robot intelligence.

Brain organoids are made from human pluripotent stem cells typically only found in early embryos that can develop into different kinds of tissues, including neural tissues.

When grafted into the brain, they can establish functional connections with the host brain, the Tianjin University team wrote in an unedited manuscript published in the peer-reviewed Oxford University Press journal Brain last month.

“The transplant of human brain organoids into living brains is a novel method for advancing organoid development and function. Organoid grafts have a host-derived functional vasculature system and exhibit advanced maturation,” the team wrote.

Li Xiaohong, a professor at Tianjin University, told Science and Technology Daily that while brain organoids were regarded as the most promising model of basic intelligence, the technology still faced “bottlenecks such as low developmental maturity and insufficient nutrient supply”.

In the paper, the team said it had developed a technique to use low-intensity ultrasound, which could help organoids better integrate and grow within the brain.

The team found that when grafts were treated with low-intensity ultrasound, it improved the differentiation of organoid cells into neurons and helped improve the networks it formed with the host brain.

The technique could also lead to new treatments to treat neurodevelopmental disorders and repair damage to the cerebral cortex, the paper said.

“Brain organoid transplants are considered a promising strategy for restoring brain function by replacing lost neurons and reconstructing neural circuits,” the team wrote.

The team found that using low-intensity ultrasound on implanted brain organoids could ameliorate neuropathological defects in a test on a mouse model of microcephaly – a neurodevelopmental disorder characterised by reduced brain and head size.

The university also said the team’s use of non-invasive low-intensity ultrasound treatment could help neural networks form and mature, providing a better foundation for computing.
 
There is absolutely no way this is real. I've seen a YT video of a team using rat neurons to make a computer capable of playing Doom (of course) and A: it looked nothing like this, B: they're still working on it and C: they're actually documenting their progress.

On point A: the neuroprocessor array the Doom guys devised had absolutely tiny amounts of actual tissue in each "chip", carefully sealed to avoid contamination or damage. This is a massive blob of meat with no protection, literally exposed to the air.

On point B: The Doom guys are still working on getting the finer points of getting neurons to acknowledge instructions down, albeit relatively successfully. These guys are claiming their robot can already do quite complex tasks.

On point C: The Doom guys are showing every single stage of their process in great detail. These Chinese guys...not so much.

What we have here is some degree of hoax, presumably to sucker some investor into giving them large amounts of money for an end product that will never materialize. I believe bio-computing may actually be a thing we eventually get, but not like this and not from them, and also not yet.

Also
>Implying the Chinese would ever be faced with a wad of living tissue and not immediately try to eat it
It looks the way a stupid person would think it should. A big brain-shaped glob in a clear dish with a very obvious connector coming out of it. It's basically Krang. And I think they designed it this way on purpose because they knew sufficiently smart people would question it no matter how it looks, so they just went the sci fi route so midwits would take it at face value.

Of course there's always a very tiny chance this is actually real in which case I'm the clownful jester in this scenario, but I'm willing to take that chance.
Every single thing from China is fake and exaggerated in some way. Their economic numbers, the strength of their military, their infrastructure (tofu dreg bridges and literal fake fire hydrants)... I'm guessing this is more bullshit until they prove it.

At the very least they took someone's brain and put it in that contraption. Probably from a member of the happy, dancing minorities filling their tolerant land. Or it's actually grown in the lab, in which case we don't have to wonder where they got the stem cells, do we?💀
I know exactly how stereotypically "mad science" this looks, and I understand the skepticism. On the other hand, we also have reports of brain organoids linked to BCIs being used as AI processors with success.



These types of experiments (i.e. linking neuronal cell cultures to computers) have been done before, with varying degrees of success:



There are companies that actually want to commercialize this, because of how efficient neuron cultures are next to, say, general-purpose computing on GPUs.



That said, there are drawbacks. Obviously, it's a living neuronal cell culture, which raises many ethical questions, but even if you put those aside, there is still the matter of keeping those cells alive and viable for an extended period without the benefit of an immune system.

So, I know it looks like pure bullshit, but it's actually sort of not bullshit.
 
I know exactly how stereotypically "mad science" this looks, and I understand the skepticism. On the other hand, we also have reports of brain organoids linked to BCIs being used as AI processors with success.
I don't doubt that brain organoids both work and could be the future of computing. What I doubt is this particular robot.
 
On the other hand, we also have reports of brain organoids linked to BCIs being used as AI processors with success.
Wow, you mean that brains are neural networks and are flesh AIs? What a twist! And we are now 0% closer to understanding, figuring out or reproducing consciousness. Just as we are exactly 0% of the way to doing to begin with.
 
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I don't doubt that brain organoids both work and could be the future of computing. What I doubt is this particular robot.
I agree. We know of other, similar experiments that have worked out in the past, but I'd like to see footage of this particular bot in action before I'd buy their claims on its capabilities.

Wow, you mean that brains are neural networks and are flesh AIs? What a twist! And we are now 0% closer to understanding, figuring out or reproducing consciousness. Just as we are exactly 0% of the way to doing to begin with.
They're using a principle called reservoir computing to make use of natural neural networks as a processing substrate for artificial ones.

I went ahead and asked Anthropic's Claude what the hell all of this actually means, and this was the answer I got:

Drain Todger: What is reservoir computing? Give both a short and simple answer, and a long, technical one, side-by-side.

Claude (3.5 Sonnet): Here is an explanation of reservoir computing, with a short simple answer and a longer technical one side-by-side:

Short & Simple: Reservoir computing is a type of machine learning that uses a "reservoir" of randomly connected nodes to process data. The connections between nodes remain fixed while only the output connections are trained. This allows reservoir computing to handle complex, time-dependent data efficiently.

Long & Technical: Reservoir computing is a computational framework that utilizes a high-dimensional dynamical system, known as a reservoir, to map input data into a higher-dimensional space. The reservoir is typically composed of a large number of randomly connected nodes, often modeled as recurrent neural networks with fixed, randomly initialized weights. The key characteristic of reservoir computing is that the internal connections within the reservoir remain unchanged during the training process, and only the output weights, which connect the reservoir to the output layer, are trained using a simple linear regression or classification algorithm.

The reservoir is designed to have a rich set of dynamics, allowing it to capture and transform the temporal information present in the input data. As the input signal propagates through the reservoir, it triggers a unique pattern of activations within the reservoir nodes. These activation patterns serve as a high-dimensional, nonlinear representation of the input data, effectively mapping the input into a feature space that can be linearly separated by the output layer.

The main advantages of reservoir computing include its ability to handle temporal and sequential data efficiently, its fast training process (since only the output weights are trained), and its robustness to noise and perturbations. Reservoir computing has been successfully applied to various domains, including time series prediction, speech recognition, robotic control, and neuromorphic computing.

Some well-known reservoir computing architectures include Echo State Networks (ESNs) and Liquid State Machines (LSMs). ESNs utilize a recurrent neural network as the reservoir, while LSMs employ a more biologically-inspired spiking neural network. Both architectures adhere to the fundamental principles of reservoir computing, relying on a fixed, randomly initialized reservoir and a trainable output layer.

Drain Todger: How can an ANN run on living brain tissue using a BCI and reservoir computing?

Claude: Here's a simplified explanation of how an artificial neural network (ANN) could potentially run on living brain tissue using a brain-computer interface (BCI) and reservoir computing:

Short & Simple: A BCI reads electrical signals from living brain tissue, which acts as a naturally complex "reservoir." These signals are fed into a computer running an ANN. The ANN learns from the brain's activity patterns to perform tasks, without altering the brain itself. The brain's dynamic complexity allows it to act as an efficient reservoir for the ANN.

Long & Technical: In the context of running an artificial neural network (ANN) on living brain tissue, a brain-computer interface (BCI) serves as the bridge between the biological neural network of the brain and the artificial neural network running on a computer. The BCI reads the electrical signals generated by the neurons in the living brain tissue, which can be treated as a naturally occurring reservoir in the framework of reservoir computing.

Reservoir computing, as mentioned earlier, utilizes a high-dimensional dynamical system (the reservoir) to map input data into a higher-dimensional space. In this case, the living brain tissue acts as the reservoir, with its inherent complexity, nonlinearity, and high-dimensional dynamics. The BCI captures the spatiotemporal patterns of neural activity from the brain, which serve as the input to the ANN.

The ANN, running on an external computer, receives the neural activity patterns from the BCI and uses them as input features. The neural activity from the brain reservoir is transformed and combined by the ANN's input and hidden layers to extract meaningful information and learn to perform specific tasks, such as pattern recognition, prediction, or control.

Importantly, the ANN does not directly alter the connections or dynamics within the living brain tissue. Instead, it learns to interpret and utilize the brain's activity patterns to achieve the desired output. The brain's natural complexity and high-dimensional dynamics make it an excellent candidate for a reservoir, as it can provide a rich and diverse set of features for the ANN to learn from.

The training process for the ANN in this setup typically involves adjusting the weights of the artificial neural connections based on the desired output and the actual output generated by the network. This is done using standard ANN training algorithms, such as backpropagation, while keeping the biological neural connections in the brain tissue unchanged.

One of the key advantages of using living brain tissue as a reservoir is its ability to adapt and reorganize in response to stimuli and learning. This plasticity of the biological neural network can potentially enhance the performance and flexibility of the combined BCI-ANN system over time.

However, it is important to note that the practical implementation of such a system is still in the realm of research and faces significant challenges, including the long-term stability of the BCI, the precision of neural signal recording, and the ethical considerations surrounding the use of living brain tissue in computational systems. Nonetheless, the concept of running ANNs on living brain tissue using BCIs and reservoir computing presents an exciting avenue for exploring the intersection of biological and artificial intelligence.

The key points are:
  1. The BCI reads neural activity from living brain tissue, which serves as the reservoir
  2. The ANN running on a computer uses the brain activity patterns as input features
  3. The ANN learns from the brain's activity to perform tasks, without changing the brain itself
  4. The brain's complexity and adaptability make it a powerful reservoir for the ANN
  5. This is still an emerging research area with significant practical and ethical challenges
Let me know if you have any other questions! The intersection of ANNs, BCIs, and living neural tissue is a fascinating area of study.

Drain Todger: Can any chaotic system with a sufficient number of states be used as a reservoir computer? Can drips of water into a bucket be used as a reservoir computer?

Claude: Yes, in principle, any sufficiently complex chaotic system with a high-dimensional state space can potentially be used as a reservoir in reservoir computing. The key requirements are that the system should have a rich set of dynamics, be able to map input data into a higher-dimensional space, and exhibit a fading memory property (i.e., the influence of past inputs on the system's state should decay over time).

Extending the concept further, even seemingly simple physical systems, such as drips of water into a bucket, can potentially serve as reservoir computers. In this case, the complex interactions between water droplets, ripples, and the bucket's surface could be seen as a high-dimensional, nonlinear dynamical system.

To use water drips as a reservoir computer, one would need to measure the state of the water surface at multiple points and times, capturing the complex spatiotemporal patterns created by the drips. These measurements could be taken using cameras, depth sensors, or other appropriate sensors. The collected data would then be preprocessed and fed into an ANN or another machine learning model, which would learn to map the reservoir's state to the desired output.

However, using water drips as a reservoir computer comes with several challenges:
  1. Measurement: Accurately measuring the state of the water surface at a sufficient spatial and temporal resolution could be difficult and require specialized equipment.
  2. Consistency: Ensuring consistent drip patterns and maintaining the same initial conditions for each computation could be challenging, as small variations in drip location, size, or timing could lead to divergent reservoir states.
  3. Evaporation and overflow: Over time, the water in the bucket will evaporate or may overflow if too many drips are added, changing the reservoir's dynamics and potentially affecting the computation's stability.
  4. Scalability: While a water drip reservoir computer could work in principle, scaling it up to tackle more complex problems might be impractical due to the physical limitations of the system.
Despite these challenges, the idea of using water drips as a reservoir computer demonstrates the broad applicability of reservoir computing concepts and highlights the potential for unconventional computing substrates. Researchers have explored various physical systems for reservoir computing, including optical reservoirs, mechanical systems, and even biological systems like slime molds.

In conclusion, while living brain tissue presents a particularly compelling substrate for reservoir computing due to its inherent complexity and adaptability, the principles of reservoir computing can be applied to a wide range of complex dynamical systems, from water buckets to slime molds. The field of unconventional computing continues to explore these fascinating possibilities.

The main takeaways are:
  1. Any sufficiently complex chaotic system with a high-dimensional state space can potentially be used as a reservoir computer.
  2. Water drips into a bucket could, in principle, serve as a reservoir computer, with the complex interactions of water droplets and ripples acting as the reservoir.
  3. Using water drips as a reservoir would require measuring the water surface state at multiple points and times and feeding this data into a learning model.
  4. Practical challenges include measurement difficulties, consistency issues, evaporation/overflow, and scalability limitations.
  5. While unconventional, this example highlights the broad applicability of reservoir computing concepts to various physical systems.
Let me know if you have any other questions! The idea of using everyday physical systems for computation is quite fascinating.

By the way, the water bucket experiment has actually been done, before.

 
Here's how this is a good thing (TM.)
AI already hallucinates completely false information, and AI engineers have thrown up their hands and said "well humans hallucinate too so it's nbd." Something tells me that fleshy brain parts are going to induce some weirdness in robots too. Instead of taking our jobs faster we're basically making tardbots to be mentally ill on the assembly line. At least your avg. human can stuff his mental illness down long enough to get home and problem-drink. So score one for the workers!
 
Chinese servitors, the solution to the 1 child policy' unintended problems.
 
>China
>Announcing ground-breaking technology without really explaining how it fucking works.
I call bullshit. That's a cheap toy with some organic slop on top that probably can't do half the things the article vaguely claims it does. Probably just a basic processor handling very basic inputs and sending similarly basic signals to a pre-programmed toy, which is interesting but not new.
You can buy about 95% of what they showed for 80 bucks. Just add some raw chicken and an old calculator and you can also fool you government for grants.
Maybe it's fake, but this manmade horror beyond your comprehension existed over 20 years ago:

A hybrot (short for "hybrid robot") is a cybernetic organism in the form of a robot controlled by a computer consisting of both electronic and biological elements. The biological elements are typically rat neurons connected to a computer chip.

This feat was first accomplished in 2003 by Dr. Steve M. Potter, a professor of biomedical engineering at the Georgia Institute of Technology
 
So, let's absolutely not teach rat brains how to play Doom, because superefficient killer rats will be the last thing our species ever invents.

fuck rats nuke rats genocide rats
 
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