I am by no means an expert but I've been carrying a variety of handguns in a variety of positions for a few years and I have some insights to share:
There is a psychological advantage to appendix carrying. I tend to wear tight fitting clothes because I work with heavy machinery and I don't want to end up on a liveleak video, but in spite of that I have had numerous occasions where people outright told me they didn't realize I was carrying, mostly for the simple reason that (normal) men don't look at each others crotches. It's a psychological blindspot. As for women, I think they just don't think about guns and assume you have a bunch of junk in your pockets. If you care about concealment but want to carry a full sized handgun and you're not a big fat fuck it's the way to go. Conversely, carrying strongside fucks up your silhouette, which is one of the first things people notice about you.
Shoulder holsters are fucking awesome if you know you're going to be seated for a long time, e.g. driving or working a desk or something, but I wouldn't recommend outside of that context. It's fairly obvious unless you've got a pretty heavy concealment garment just because there's really nothing else it could be in that position, people are going to assume "gun" right away. It also just feels less secure, and that's going to affect how you move with it, which can be a tell, but more importantly it's just really annoying. Maybe a skill issue, idk, but that has been my experience anyway.
In the winter I keep a snubnose 38 in my jacket pocket specifically because it can be fired from concealment; if I flip it upside down, i.e. grip up and muzzle pointed behind me, it's a LOT less conspicuous. If things start to look sketchy I just pull the grip up and back to reorient it into a proper position. It's hard to explain and probably sounds retarded but it works well enough for that particular use case.