I think internationally targeted anime is inevitable in the future. Anime/manga more than ever is mainstream. You have normies encountering this weird otaku shit and not liking it and latching on to the popular shonen of the time instead. I'd love to see how much Devilman Crybaby made, since that was internationally produced/funded and released on Netflix.
I will say I've liked some of the creativity being displayed by newer productions, though. I like how Demon Slayer has an effective arc for most if not all of its characters, for example.
I don't know ho much of the core of anime will change even with these international audiences. Woketards bitched about an MHA character having jugs or something but the Japanese producers are ultimately concerned with the Japanese market, they probably don't see a lot of, if any of the money western consumers throw to their products. Maybe Japanese companies' tunes will change if/when they do make the shift to international marketing, who knows.