Just picked this back up yesterday after a single playthrough when it released, I'm having a lot of fun so far but I'm still very early game- Level 3, exploring the beach and Fort Joy area still, getting a feel for the companions and for the way battle works all over again. I picked Ifan as my origin character because I just plain old really like him, and picked up Lohse, Fane, and Red Prince- I played as a custom character my first run and had Sebille, Ifan, and Beast, so it seems appropriate to see the other ones as well. A lot of details are fuzzy after over half a decade, so whilst it's not a brand new experience, I'm pretty happy I get another go at experiencing the story. I'll be pretty gutted when Beast dies, but at least he won't get mad if I decide to be mean about dwarves.
So far and without min/maxing too terribly as well as with the knowledge that I can respec upon leaving Act 1, I have Ifan with an archer/summoner build in mind, Geo/Pyro Red Prince, Fane as an Inquisitor with a Necromancy slant, and Lohse on Aero and Hydro. I'm a bit worried about the lack of synergy between Red Prince and Lohse, but I'm not playing on the hardest mode and again, I can always respec if I need to. Any thoughts on anything I should definitely grab or something I haven't considered?