1- Default Uniform: dumb uniform, dumb school. Less people means more opportunities to murder. Lesson times are shorter, which gives the player less stat points to allocate, but also more free time. All the animu tropes and memes. A person can easily get through the game by murdering everyone.
2-Typical Japanese High School Uniform: Decent school with a medium population. People aren't as oblivious (wider vision range). Fair amount of points to allocate, but less free time and less opportunities to commit crimes. People act more like a typical person in real life, and thus, strangeness isn't as tolerated. This level forces a person to use other means of elimination besides murder, unless they know how to execute it well (may require more than one playthrough).
3-Prestigious uniform: Large, intelligent population. Rules are strictly enforced and people are intuitively sharp (wider vision, less tolerance for strange behaviour). The students are all here to achieve academically, and are less likely to make friends as a result. School time is longer, which gives more stat points, but there are very few opportunities to straight up murder someone. A person playing this level has to use all sorts of ingenious methods to eliminate rivals and focus on building their stats in order to win.