With the dropping of support for 32-bit PhysX in the Blackwell series, a user tried to fix the performance problem by adding another NVIDIA GPU that comes with PhysX support. The Redditor u/jerubedo tried adding a GeForce RTX 3050 to his gaming PC alongside the GeForce RTX 5090 (this isn't SLI) and dedicated the RTX 3050 strictly for PhysX processes in the NVIDIA Control Panel.
He then ran and benchmarked a couple of PhysX-based games, including Mafia II Classic, Batman Arkham Asylum, Borderlands 2, Assassin's Creed IV: Black Flag, and Mirror's Edge. The final results show an improvement of up to 1425%.