How are they going to make Vice City look distinctive in the HD era? That's a hard act to follow.
They're not going to even try. The (zoomer/millennial) money is in making everything contemporary, not in a stylized vision that overrides potential profit.
Expect a current-day Miami, which outside of Miami Beach is ugly as shit and has 0% of that faux-80s glitz.
Since IV, R* has had a priority in making their worlds cutting-edge detailed and graphically impressive. Style, atmosphere, and fun take a far-back seat.
No seriously, check the interviews; they always use words like "most detailed" or "most realistic" when describing their new settings post-SA. Never "most fun". I particularly remember them being excited about how it would originally take you an hour to get from edge of Liberty City to another (lol) and how they made glass-breaking animations for vehicles rather than sell you on how much fucking fun you would have or how much customization would be improved (lol x2).
Then there's their eternal unicorn since VC; life-like Peds/NPCs. They've always promised that their 'next-gen' AI means pedestrians and NPCs are completely independent of the player and that if you choose, you can stalk one at random and watch them live out their lives; go to work, go home, socialize, and eventually ascend in their lives or be left on the streets. Then post-launch they explain that the technology "just wasn't there yet" (true, but it'll never be at that point anyway. Having an AI that runs itself millions of times simultaneously is going to be stressful on all but the most beefy CPUs, so maybe just stop saying this time you really got it down).
I think that at the very least GTA 6 will have a fun sandbox, story will probably suck ass and have shitty references to cringe leftoid politics, and will probably feature Not-Trump and Not-Proud Boys being a enemy who is both incompetent but also a threat to all of America and must be stopped. The game will probably have some BLM shit in it and Cops will probably be overtly racist, and all the other awful ideas we can think of, but at least running over pedestrians in a car will be fun.
Forget about all that; the nigger music will be most of the content featured on the radio except for the homosexual urbanite station and the hipster station. Fucking hell, can we at least get a Spotify/AM/Pandora/etc station on consoles akin to the MP3 Player/Independence FM/Self-Radio stations on PC?