Medical Advice Thread - Does this look infected?

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So since last summer I've noticed that Claritin makes my heart rate spike, usually at night. It wasn't anything too bad, usually it just jumps to 110 for a half hour or so and goes away. Tried switching to Allegra, did the same thing. A few days ago I tried just a regular Benadryl before bed and I woke up two hours later sweating with my heart rate at 145. This lasted for 3 hours and I almost went to the emergency room. Since then I haven't taken anything and feel fine, haven't had anymore episodes. I've been on allergy meds my whole life and have never had this happen and I'm kinda paranoid this might be a sign I have something going on with my heart since I know antihistamines can cause this in people with underlying heart conditions. I just saw my ENT and my blood pressure is fine, but should I bug my GP for a stress test or something? Does this mean I can never do meth again? :c
Ask for an ECG.

Arrhythmia like that is not to be taken lightly.
 
After years of being practically non-functioning with pain, joint problems, atrocious stomach issues and bladder problems, and a whole host of other crap, get diagnosed with EDS. A while later "heart issues" that are essentially POTS (I actually neglected to follow this up hence the later diagnosis because fainting every day sounds like bullshit and I sound like a munchie and I hate it). I literally got the combo munchie platter diagnosis and I don't talk to anyone about it because that is so embarrassing and sounds like I'm completely full of shit despite struggling every second of the day and trying so hard. I desperately wish I could fix myself and have tried everything under the sun bar seeing all the EDS professionals that I'm worried are just vultures because of what has been shared about people like them in MBI threads here. (Yes my back discs are degrading at a very impressive rate no I don't want spinal fusion)

Go unnoticed for years because you don't know all these problems are connected or how to voice it, then start advocating for yourself but feel like a fucking retard because everyone online with EDS seems to act like a virtue signalling retard who doesn't even want to get better and it makes me feel like I too am full of shit despite being absolutely physically fucked
 
This is a long shot, but has anyone on here dealt with pyroluria?
No, but anything involving leaky gut can - according to anon right wing bodybuilders on twitter (who were 100% correct about everything RE wu flu in june of 2020) - be improved by eating things that contain collagen. Pork rinds, organ meat, chicken skin, bone broth (relatively easy to make your own if you have room), joint gristle, any sort of connective tissue, and of course collagen powder or glycine. It's helping my skin heal faster, and my liver is a little stressed so we'll see if it helps with that along with losing weight. It probably couldn't hurt so long as you aren't eating a scoop with every meal.
 
@MysticLord Regarding the hypothyroidism, did they determine a root cause? I'm going to guess it was Hasimoto's Thyroiditis? If so, do you have any other concurrent autoimmune issues, or this is the first one? With the new onset hypothyroidism, have you seen a significant amount of weight gain? If so, this is likely the trigger for your current upper GI issues. Weight gain is a common cause of upper GI issues, usually exacerbating what was previously a silent hiatal hernia, which commonly has the positonal presentation you mentioned you are seeing manifest. If you want to avoid what is likely to be a significant amount of radiation involved in imaging, an endoscopy and/or an abdominal ultrasound is just as likely to be diagnostic. If the endoscopy and ultrasound came out clean, then a CT would be warranted; I am just generally quite hesitant to suggest imaging involving non-trivial dosing of ionizing radiation if another modality can be used.

I remember reading a while back that you only absorb like 20% of Vitamin D taken through supplement so you should get 500% your daily recommended Vitamin D. Any truth to this?

That is only true for D2, not D3. This is why D2 is dosed at 50,000 IU. For D3, try to make your dosing twice a day if your D3 requirement is on the higher end as it is possible to saturate the D3 transporters in your gut if you are taking more than 5,000 IU in a single dose. Never take more than 10,000 IU per day unless you are absolutely 100% sure you need it. To establish that you would need two consecutive D3 levels below normal over 12 months time (so, 6 months after you start 10,000 IU, and again 6 months after that) with one test being done in March/April and the next one in August/September (since those represent the nadir and peak respectively for D3 levels in a given year).

For anyone taking 10,000 IU (or more) consider a Vitamin K1 (not K2) supplement as well (phylloquinone, not phytonadione, which is crap), since it is the other important vitamin that is part of the calcium balance system. Absolutely do not start taking Vitamin K if you have any type of clotting disorder, take other medications that impact your clotting (such as asprin) , or you have a known cerebrovascular or cardiovascular condition.

So since last summer I've noticed that Claritin makes my heart rate spike, usually at night. It wasn't anything too bad, usually it just jumps to 110 for a half hour or so and goes away. Tried switching to Allegra, did the same thing. A few days ago I tried just a regular Benadryl before bed and I woke up two hours later sweating with my heart rate at 145. This lasted for 3 hours and I almost went to the emergency room. Since then I haven't taken anything and feel fine, haven't had anymore episodes. I've been on allergy meds my whole life and have never had this happen and I'm kinda paranoid this might be a sign I have something going on with my heart since I know antihistamines can cause this in people with underlying heart conditions. I just saw my ENT and my blood pressure is fine, but should I bug my GP for a stress test or something? Does this mean I can never do meth again?
:c

It's not your heart, you're experiencing an acute anticholinergic syndrome. However, something like Claritin, Allegra, or a single Benadryl should never trigger this. The only reason this would happen is if you are taking other medication that have anticholinergic properties, or you are extremely sensitive to anticholinergic medications. This type of reaction is very unusual. Has this happened in the past or just recently? Besides tachycardia, do you have any other symptoms of acute anticholinergic syndrome (dilated pupils, dry mouth, unusual difficulty concentrating, etc...)? If this is just recent, and you don't take any other medications with anticholinergic properties it either speaks to a new onset idiotpathic anticholinergic hypersensitivity or some type of cholinergic imbalance.
 
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I have PCOS and am on the depo shot. My gyno has increased my depo shot to every two months because of breakthrough bleeding and period flu PMS. Despite being on birth control, my scumbag ovaries like to randomly hurt. My breakthrough bleeding has yet to stop. My reproductive tract is like a mucus factory. Help.

Do I just go and get a complete hysterectomy in Mexico?

Also, my gyno and nurse practitioners are my coworkers. It breaches medical ethics to bug them as Lurk_Moar, MLT (ASCP) while being on the clock in a white coat instead of just Lurk_Moar the patient who has to make an appointment just like everybody else.

I can also interpret your lab results in this thread.
I'm sorry you're going through that. I heard that inositol can help with PCOS (and OCD but that's off topic). Are you on any androgen blockers like spiro? Are you a normal BMI? Have you ever considered taking boron for your bones? I wanted the bc shot but my dr. wouldn't allow it bc she said it thins bones.
Should someone be worried with a CRP of around 30 in all three tests I've had? Been dealing with chronic fatigue for yrs but never had my inflammation tested before last yr. Just a few random autoantibodies like RF and ANA, which were negative. I've had psoriasis since I was kindergarten age.
GP said it could be autoimmune but getting me into a rhem would take two yrs and they might blow me off. Every other blood test has always been normal, CRP is the first thing that has ever been "off" about my blood work. GP said fatigue plus elevated CRP is not enough for a rhem to go on.
But I feel like elevated CRP + decades of psoriasis + years of chronic fatigue is enough to at least suggest something? My next plan is to ask her to test me for anti-CCP antibodies.
I'm also getting white hairs in my 20s, have heat intolerance, fast heartbeat and visual snow. I also have tremors when trying to do things, which I think is called intention tremors but my doctor thinks it's from Wellbutrin. What does this sound like?
WRT testing, along with clean bloods except for CRP I've had a normal EKG, normal brain MRI and a pelvic ultrasound where they didn't seem worried but when I asked about it she said one ovary was not visible and one was enlarged but not cystic, and retroverted uterus. I take continuous combined birth control bc my period annoys me and is terrible and my one time gyno surgeon said it was fine.
So since last summer I've noticed that Claritin makes my heart rate spike, usually at night. It wasn't anything too bad, usually it just jumps to 110 for a half hour or so and goes away. Tried switching to Allegra, did the same thing. A few days ago I tried just a regular Benadryl before bed and I woke up two hours later sweating with my heart rate at 145. This lasted for 3 hours and I almost went to the emergency room. Since then I haven't taken anything and feel fine, haven't had anymore episodes. I've been on allergy meds my whole life and have never had this happen and I'm kinda paranoid this might be a sign I have something going on with my heart since I know antihistamines can cause this in people with underlying heart conditions. I just saw my ENT and my blood pressure is fine, but should I bug my GP for a stress test or something? Does this mean I can never do meth again? :c
Maybe ask for an EKG, it can tell you a lot of stuff about your heart.
 
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I'm sorry you're going through that. I heard that inositol can help with PCOS (and OCD but that's off topic). Are you on any androgen blockers like spiro? Are you a normal BMI? Have you ever considered taking boron for your bones? I wanted the bc shot but my dr. wouldn't allow it bc she said it thins bones.
Should someone be worried with a CRP of around 30 in all three tests I've had? Been dealing with chronic fatigue for yrs but never had my inflammation tested before last yr. Just a few random autoantibodies like RF and ANA, which were negative. I've had psoriasis since I was kindergarten age.
GP said it could be autoimmune but getting me into a rhem would take two yrs and they might blow me off. Every other blood test has always been normal, CRP is the first thing that has ever been "off" about my blood work. GP said fatigue plus elevated CRP is not enough for a rhem to go on.
But I feel like elevated CRP + decades of psoriasis + years of chronic fatigue is enough to at least suggest something? My next plan is to ask her to test me for anti-CCP antibodies.
I'm also getting white hairs in my 20s, have heat intolerance and visual snow. What does this sound like?

Maybe ask for an EKG, it can tell you a lot of stuff about your heart.

Holy fucking Jesus Christ, a CRP of 30 is awful depending upon the methodology, units, and analyzer used. You gots lots of inflammation in your body, girlfriend. Did the doctor do a sed rate to go along with that CRP? Inflammation for sure causes fatigue.

I take calcium and vitamin D for my bones. I am not taking inositol. I was taking it, and it did nothing. One brand totally crashed my already low blood sugar. My normal random glucose is in the 80's. I saw my glucose in the low 100's twice in my life, non-fasting of course. My A1C is about 4.6. I took metformin which did absolutely nothing and high doses caused me to vomit. Sugar and carbs cause my blood sugar to crash harder than Lindsay Lohan, lol. I probably make too much insulin.

My BMI is 23.8, and I weigh 118 pounds. I am on a very high protein, low calorie diet while doing lots of exercise. I did 40 minutes of weights today and going to do some speed walking on the treadmill later.
 
Holy fucking Jesus Christ, a CRP of 30 is awful depending upon the methodology, units, and analyzer used. You gots lots of inflammation in your body, girlfriend. Did the doctor do a sed rate to go along with that CRP? Inflammation for sure causes fatigue.

I take calcium and vitamin D for my bones. I am not taking inositol. I was taking it, and it did nothing. One brand totally crashed my already low blood sugar. My normal random glucose is in the 80's. I saw my glucose in the low 100's twice in my life, non-fasting of course. My A1C is about 4.6. I took metformin which did absolutely nothing and high doses caused me to vomit. Sugar and carbs cause my blood sugar to crash harder than Lindsay Lohan, lol. I probably make too much insulin.

My BMI is 23.8, and I weigh 118 pounds. I am on a very high protein, low calorie diet while doing lots of exercise. I did 40 minutes of weights today and going to do some speed walking on the treadmill later.
She did not do a sed rate bc she said they are older and not very accurate. I'm in Canada, I think maybe my province has a rhem shortage? Maybe a derm can look at my joints for signs of Psoriatic arthritis? I feel like there are more derms here than rhems. I don't feel any pain though... never have, which doesn't scream arthritis.
Oh damn, I didn't even know inositol could do that, good for you for having such a healthy BMI though. There is a meme on the deathfats forum that "PCOS is a fatty disease" lol. Thanks Whitney Weighs More.
I take boron because the Examine.com review said it helps inflammation plus it's good for bones, so maybe it would help you? Metformin sounds like a shitty drug tbh. It's like those immune suppressants like methorexate I'm scared I'll be prescribed if I do end up having an autoimmune disorder.
 
I'm sorry you're going through that. I heard that inositol can help with PCOS (and OCD but that's off topic). Are you on any androgen blockers like spiro? Are you a normal BMI? Have you ever considered taking boron for your bones? I wanted the bc shot but my dr. wouldn't allow it bc she said it thins bones.
Should someone be worried with a CRP of around 30 in all three tests I've had? Been dealing with chronic fatigue for yrs but never had my inflammation tested before last yr. Just a few random autoantibodies like RF and ANA, which were negative. I've had psoriasis since I was kindergarten age.
GP said it could be autoimmune but getting me into a rhem would take two yrs and they might blow me off. Every other blood test has always been normal, CRP is the first thing that has ever been "off" about my blood work. GP said fatigue plus elevated CRP is not enough for a rhem to go on.
But I feel like elevated CRP + decades of psoriasis + years of chronic fatigue is enough to at least suggest something? My next plan is to ask her to test me for anti-CCP antibodies.
I'm also getting white hairs in my 20s, have heat intolerance, fast heartbeat and visual snow. I also have tremors when trying to do things, which I think is called intention tremors but my doctor thinks it's from Wellbutrin. What does this sound like?
WRT testing, along with clean bloods except for CRP I've had a normal EKG, normal brain MRI and a pelvic ultrasound where they didn't seem worried but when I asked about it she said one ovary was not visible and one was enlarged but not cystic, and retroverted uterus. I take continuous combined birth control bc my period annoys me and is terrible and my one time gyno surgeon said it was fine.

Maybe ask for an EKG, it can tell you a lot of stuff about your heart.

Sweet Jesus. A CRP of 30 is very concerning. It's most likely a function of what is going on with your psoriasis, but that means it is causing an incredible amount of inflammation. The current understanding of psoriasis is that it is a combination of autoimmune and autoinflammatory dysregulation. Psoriasis without joint involvement would probably best be handled by a dermatologist. Without any obvious impact on the joints a rheum is likely to shrug. If possible, the best medication current for psoriasis is Otezla (Apremilast). It is very effective, and doesn't increase your cancer risk or cause PML (your brain basically liquefies, and it can't be cured) like the monoclonal antibody therapies. However, it can make depression worse (the mechanism behind this is unknown) so that is something to keep in mind.

The fast heartbeat and visual snow, is it more likely to happen when you change position, such as sitting or lying down to standing? I take it the Wellbutrin is for depression? Also, before the birth control, was your period irregular? (I ask because it would fit what I am thinking about as far as a potential answer to what is going on)
 
Hey guys. If anyone has got any insight to share, I'd welcome it.

As it is, I can't talk to anyone about these test results until well into March due to shit healthcare services where I live - so I would love to see what you guys think.

Is there anything I can do to feel better in the meanwhile, beyond supplements?

I have been diagnosed with Hypothyroidism in the past (thanks ma), and was on levothyroxine for years. When I complained of fatigue, brain fogginess, trouble staying warm etc, I got thyroid levels checked up last year (despite no longer being on medication, long story) - the doctor that checked my levels was baffled because TSH and free T4 levels were fine. He said sometimes you can get transient hypo from viral infections and what not, so apparently thyoid problems aren't the likely problem.

That blood test showed abnormal high lymphocytes (nothing extreme 3.5, when the highest range is 3.0) and "highest end of the reference range basophils", but otherwise there was nothing else noteworthy.

---------------

Fast forward to this week (still suffering from the same fatigue, etc), when I had a blood test done on Monday. Test included a full blood count, TSH levels, liver enzymes, kidney test.

Abnormal test results (defined as outside the reference ranges given by the lab):

High lymphocytes (outside high reference limit)
High basophils (outside high reference limit)
Serum folate (outside low reference limit)
Vitamin D (outside low reference limit)

Should I be concerned about the higher levels of WBC in the test result? They were the same ones that were already high on that first blood test last year.

Could these wonky results be due to the deficiency in vitamin D and folate? I will add that I have really shit health in general, with frequent infections, (LUTS, about every month).




f0629d0c7a22e7ff005b4db87aa605b9.png6f84e4bd510d40811dc2c0c9c61c1160.png
 
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Hey guys. If anyone has got any insight to share, I'd welcome it.

As it is, I can't talk to anyone about these test results until well into March due to shit healthcare services where I live - so I would love to see what you guys think.

Is there anything I can do to feel better in the meanwhile, beyond supplements?

I have been diagnosed with Hypothyroidism in the past (thanks ma), and was on levothyroxine for years. When I complained of fatigue, brain fogginess, trouble staying warm etc, I got thyroid levels checked up last year (despite no longer being on medication, long story) - the doctor that checked my levels was baffled because TSH and free T4 levels were fine. He said sometimes you can get transient hypo from viral infections and what not, so apparently thyoid problems aren't the likely problem.

That blood test showed abnormal high lymphocytes (nothing extreme 3.5, when the highest range is 3.0) and "highest end of the reference range basophils", but otherwise there was nothing else noteworthy.

---------------

Fast forward to this week (still suffering from the same fatigue, etc), when I had a blood test done on Monday. Test included a full blood count, TSH levels, liver enzymes, kidney test.

Abnormal test results (defined as outside the reference ranges given by the lab):

High lymphocytes (outside high reference limit)
High basophils (outside high reference limit)
Serum folate (outside low reference limit)
Vitamin D (outside low reference limit)

Should I be concerned about the higher levels of WBC in the test result? They were the same ones that were already high on that first blood test last year.

Could these wonky results be due to the deficiency in vitamin D and folate? I will add that I have really shit health in general, with frequent infections, (LUTS, about every month).




High basophils, known as basophilia, that is just outside the reference range isn't uncommon for someone with hypothyroidism. However, you usually only see it if the hypothyroidism is manifest. TSH is normal, but I'd be interested in T3, as well as T4. I'm kinda surprised they didn't include that. The high lymphocytes, known as lymphocytosis, seems to be improving, 3.5 to 3.05, so ever so slightly outside the reference range. However, the fact that it's been high twice in a row is concerning. Did they determine the cause of your hypothyroidism? If it was autoimmune in nature, that could explain why the lymphocytes are high, since a disorder like hashimoto's thyroiditis is actually caused by the inappropriate behavior of the lymphocytes attacking the thyroid. If your hypothyroidism was not caused by an autoimmune syndrome, then chronic lymphocytosis with no overt symptoms would be a good indicator of a viral infection. I wish they had included a liver function panel, would have helped to rule out a bunch of stuff.

Your vitamin D is awful. I would start supplementing that ASAP. I'd probably start at 5000 IU once a day and recheck in 6 months (it takes about 6 months to see the full change from vitamin D supplementation). You'll want to supplement with D3, not D2. The D2 stuff, in general, is crap. 5000 IU probably seems like a ton, but your levels are so low, it is going to take quite a bit to get you back into the healthy range (which is 70-80, 50 is really the absolute minimum for normal function, and many argue that is still too low). Addressing the low folate with supplementation is a good idea. In case the low folate is being caused by a common mutation where your body sucks at properly synthesizing the useful form of folate you'll want to get folate in the form of 5-Methyltetrahydrofolate also called 5-Methyltetrahydrofolic acid or 5-MTHF. If you have the mutation in question, you lack the ability to convert folic acid into useful folate so typical folic acid is literally useless. Getting folate in the 5-MTHF form allow for one to bypass the mutant enzyme that doesn't work.

Getting your vitamin D levels into the normal range should help with the chronic infections. The immune system actually depends on vitamin D to function correctly. Without it, it malfunctions. Once it's in the normal range, I think you will be amazed at how much better you feel.
 
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Thank you so much for your help! It's rather hard to get prompt advice these days. I will look into proper supplements this weekend - anything to feel better soon.:heart-full:

I admit that I am not sure what is happening with the Hypo situation anymore, at all.

All I know is that I got diagnosed with some kind of Hypothyroidism back 12 years ago, and was on a dose of 75mg levothyroxine for a while. Then after a long time of eventually running out of medication (years), I got access to affordable healthcare again. I got my thyroid levels tested by the public GP services and they said TSH was "normal", and no action was required. They only tested for TSH specifically: ((Serum TSH level 2.80 mIU/L [0.27 - 4.2]))

Now, I knew I was feeling like shit and I *had* a previous diagnosis of some kind of hypo, so I wasn't totally convinced and I got that test done in 2021, again, privately this time. The doctor that ordered this one agreed that hypo doesnt magically cure itself out normally, and in this test I got the following results:

TSH: 2.680 (range 0.27-4.20)
Free T4: 20.50 (range 12-22)

WBC count: 8.5 (range 4.0-10.0)

Neuts: 3.7 (2.0-7.0)
Lymphs: 3.5 (1.0-3.0)
Monos: 0.9 (0.2-1.0)
Eos: 0.4 (0.0-0.5)
Basos: 0.1 (0.0-0.1)

So I have one result that is presumably TSH only (2020-2021), one other that shows medium* range TSH, high range FT4 (july 2021), and the most recent which just shows low TSH (2022).

For context: test 1 and test 3 have been done through public funded healthcare so generally doctors will only ever test TSH for thyroid function. T4 is tested next if TSH is abnormal, but I've never, ever had T3 tested in these three tests.

I suspect that my original diagnosis might have been from wonky T3 levels, from tests done privately back when I lived abroad. But it will be an uphill battle to get this investigated properly, because as I explained before it is hard to get my current doctors to order a full thyroind screen without passing the "abnormal TSH" gatekeep.

I do have access to liver results from this most recent test if it helps:

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Liver is solid, so that's a decent r/o for chronic virus. The rest of the differential is fairly consistent. You have a 1st degree female relative with hypothyroidism? That would be another check in the list for hypothyroidism. It is possible to see transient hypothyroidism as a result of an infection but that would be a diagnosis of exclusion and there just isn't enough information to do that. Are you seeing any of the symptoms you saw before? (fatigue, brain fogginess, trouble staying warm, etc...). The chronic lymphocytosis, basophilia, and history of hypothyroidism all add up to something akin to chronic lymphocytic thyroiditis, but possibly a subacute presentation rather than an acute presentation. Subacute lymphocytic thyroiditis is tricky. You can see period of hypothyroidism, but then it can transition back to a euthyrotic state (Euthyroid is what is considered "typical" or expected normal thyroid function) and if the testing it done just at the wrong time, it can appear that everything is ok, but it's just because it's in the euthyrotic phase. Instead of messing with TSH & T4 levels the better test to do would be antithyroid autoantibodies. That is the definitive test. If it comes back positive, it's thyroiditis, it's just down to figuring out the exact type and treatment at that point.

It is entirely possible that the low levels of vitamin D are a major player in this situation. Low levels of vitamin D are known to have a strong tie to autoimmune behavior and thyroid dysfunction. Before running the antithyroid autoantibody test (which is most likely going to be a hard sell to the GP, as despite it being the best and most definitive test, there is a strong chance it is not cheap) a sincere attempt to get your Vitamin D levels up above 50 first would probably be a good idea. Once your immune system gets up and running properly it is possible the autoregulatory component could reign in any current attack on your thyroid and help ameliorate symptoms you are experiencing. However, if you have autoantibodies against the thyroid, Vitamin D won't cure that, but it might improve the symptoms. If after 6 months your Vitamin D levels are in the normal range, but you are still seeing the lymphocytosis, I would press for the antithyroid autoantibody test to find out once and for all if you have thyroiditis. If you don't, then a referral to determine the true nature of the lympocytosis would be important because chronic lympocytosis doesn't happen for no reason. If you do, then a referral to an endocrinologist to determine what is going on with your thyroid and how to treat it would be the best way to go.
 
Yeah, thyroid dysfunction runs strongly in the family. My mother has hypothyroidism (last I remember she was on 125 levothyroxine a day), and I believe there is some on my father's side as well. My father was treated for hyperthyroidism in his late 50s, a couple of years ago.

I have all the symptoms of Hypo and what is frustrating is that while the thyroxine didn't seem to make a noticeable improvement while I was taking it - without it, these days, its become much worse.

- Particularly noticeable is hair loss, noticeable weight gain despite 1600cal/day (after a successful gastric sleeve that saw me lose and keep off half my BW). I'm not overweight at the moment (healthy BMI range).
- Puffy face, particularly eyelids, sluggishness
- I can sleep for 15 hrs a day (average is 10-11), I'm always fatigued, my memory is fucking shot to pieces, dry skin, bowel slow, MDD, you name it. The fatigue has always been crippling QOL-wise, but dxed as depression (was on sertraline for years).
- Even now im on on a low dose of amitriptyline for mild neuropathy, because it helps me cope with chronic inflammation LUTS symptoms. My joints (particularly my knees) hurt daily, I'm 32. Ooops!

**I don't have a previous history of any nutrient deficiencies before this latest blood test!
(:_(

I'm worried as fuck because I can't understand how I could just get a hypo dx and medication out of the blue all those years ago, but I'm having to fight tooth and nail to get a proper thyroid function test these days. I wish I could remember the details of that original Dx because at this rate I've been without any kind of thyroid support for years. The ADHD medication helped address functional brain problems, but I'm physically still hecking tired as fuck.

The only time I feel vaguely functional (mentally) is on the meth 9 hr window, and I have to limp through the rest of the day with 2 to 3 red bulls (I know. It sucks. But I cannot cope otherwise.)

Also worrying is the fact that I have to keep looking out for weird periods of palpitations and other fun side effects of taking methylphenydate as medication for adult ADHD. I shouldn't be topping up with caffeine, but I don't know what else to do. So if there's even the slightest change that my thyroid is all over the place, I need to know about it because anything affecting cardio effects must be risk-assessed and I legit cannot function without being on a stimulant. Though ideally they'd find a way to help me with the physical symptoms of being hypo so I wouldn't have to self medicate with caffeine (I wouldn't dream of upping my meth dose).

I'll get started on those supplements immediately, and talk to my GP in March. She probably will talk about the deficiencies and sweep the hypo under the carpet, but I guess I might be able to scrounge enough money for a private full thyroid screen in 6 month's time.

Thank you so much man, this has been mega helpful! All the kudos to you.

:semperfidelis:
 
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Sweet Jesus. A CRP of 30 is very concerning. It's most likely a function of what is going on with your psoriasis, but that means it is causing an incredible amount of inflammation. The current understanding of psoriasis is that it is a combination of autoimmune and autoinflammatory dysregulation. Psoriasis without joint involvement would probably best be handled by a dermatologist. Without any obvious impact on the joints a rheum is likely to shrug. If possible, the best medication current for psoriasis is Otezla (Apremilast). It is very effective, and doesn't increase your cancer risk or cause PML (your brain basically liquefies, and it can't be cured) like the monoclonal antibody therapies. However, it can make depression worse (the mechanism behind this is unknown) so that is something to keep in mind.

The fast heartbeat and visual snow, is it more likely to happen when you change position, such as sitting or lying down to standing? I take it the Wellbutrin is for depression? Also, before the birth control, was your period irregular? (I ask because it would fit what I am thinking about as far as a potential answer to what is going on)
Okay, sounds like the derm is a good thing to ask about then. I've always taken topicals for pso but for yrs I've just been using non medical moisturizers. It's been more than a decade I've seen a derm though. I've heard good things about Otzela too bc there was a meta-analysis I read that said it doesn't up your cancer and infection risk.
I think the Wellbutrin is for depression or something like that but haven't seen a psychiatrist in over 10 yrs, but when I did he diagnosed me with clinical depression and OCD. My GP prescribes and manages psych meds.
I actually know about PML, only bc I have been trying to figure out what is causing my fatigue so I researched MS for a while. PML sounds terrifying. It's so shitty how many MS treatments can cause it bc it's like MS degeneration in hyperspeed.
The visual snow is the same whether moving or not and I've had it all my life, even when I was 2. It used to scare me when I was trying to sleep bc it's there whenever I'm conscious, even when my eyes are closed. But my mom said it was normal to get me to sleep so I just accepted it and it didn't bother me after that. I was diagnosed twice in school with NVLD by a neuropsych, which I think points to issues in some brain areas. It's a learning disability sometimes compared to Aspergers but I feel the visual processing issues a lot more than the autistic social problems.
My period was normal, seemed to last forever and really messed up my mental health for some reason. I think it lasted about a week usually, but turns out I had a micro-perforate hymen that I got removed surgically. I thought it was normal for a tampon to hurt like hell and that everyone experiences this.
 
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@Tijuana Bible

I look at people's lab results for a living and study them in college.

Your lymphocyte and basophil counts are just slightly elevated but nothing to worry about. I am not concerned whatsoever about your lab results.

Since you are still experiencing symptoms of Hashimoto's, you need to have a thyroid peroxidase antibody test done.
 
Yeah, thyroid dysfunction runs strongly in the family. My mother has hypothyroidism (last I remember she was on 125 levothyroxine a day), and I believe there is some on my father's side as well. My father was treated for hyperthyroidism in his late 50s, a couple of years ago.

I have all the symptoms of Hypo and what is frustrating is that while the thyroxine didn't seem to make a noticeable improvement while I was taking it - without it, these days, its become much worse.

- Particularly noticeable is hair loss, noticeable weight gain despite 1600cal/day (after a successful gastric sleeve that saw me lose and keep off half my BW). I'm not overweight at the moment (healthy BMI range).
- Puffy face, particularly eyelids, sluggishness
- I can sleep for 15 hrs a day (average is 10-11), I'm always fatigued, my memory is fucking shot to pieces, dry skin, bowel slow, MDD, you name it. The fatigue has always been crippling QOL-wise, but dxed as depression (was on sertraline for years).
- Even now im on on a low dose of amitriptyline for mild neuropathy, because it helps me cope with chronic inflammation LUTS symptoms. My joints (particularly my knees) hurt daily, I'm 32. Ooops!

**I don't have a previous history of any nutrient deficiencies before this latest blood test!
(:_(

I'm worried as fuck because I can't understand how I could just get a hypo dx and medication out of the blue all those years ago, but I'm having to fight tooth and nail to get a proper thyroid function test these days. I wish I could remember the details of that original Dx because at this rate I've been without any kind of thyroid support for years. The ADHD medication helped address functional brain problems, but I'm physically still hecking tired as fuck.

The only time I feel vaguely functional (mentally) is on the meth 9 hr window, and I have to limp through the rest of the day with 2 to 3 red bulls (I know. It sucks. But I cannot cope otherwise.)

Also worrying is the fact that I have to keep looking out for weird periods of palpitations and other fun side effects of taking methylphenydate as medication for adult ADHD. I shouldn't be topping up with caffeine, but I don't know what else to do. So if there's even the slightest change that my thyroid is all over the place, I need to know about it because anything affecting cardio effects must be risk-assessed and I legit cannot function without being on a stimulant. Though ideally they'd find a way to help me with the physical symptoms of being hypo so I wouldn't have to self medicate with caffeine (I wouldn't dream of upping my meth dose).

I'll get started on those supplements immediately, and talk to my GP in March. She probably will talk about the deficiencies and sweep the hypo under the carpet, but I guess I might be able to scrounge enough money for a private full thyroid screen in 6 month's time.

Thank you so much man, this has been mega helpful! All the kudos to you.

:semperfidelis:

I take it when you were on the levothyroxine your symptoms improved? If so, I think presenting your GP with a 3 pronged ultimatum would be the best approach. 1) Ask her to run the antithyroid autoantibody test. 2) If not, start you on a low dose of levothyroxine and see how you do. This is known in medicine as "empirical treatment". It is often used when a treatment is likely to help, even if the evidence for its use is not necessarily strong at the time. Particularly since you have been on it before, and if you saw improvement, that would strongly support an empirical treatment trial. I would emphasize with the GP that you know what the signs of hyperthyroidism look like, and if you develop any adverse effects while on the levothyroxine you would stop immediately and contact your GP to ask them what they want you to do. This would reassure them that you are responsible and understand the potential benefits and risks of an empirical treatment trial. 3) If the GP won't do either of those, tell them you want a definitive diagnostic pathway going forward that will allow for the determination of what is afflicting you since it is destroying your quality of life, and if they can't or won't do that, tell them to pick one of the other two options, but not doing anything is unacceptable.

Your symptoms are so strongly indicative of subacute chronic lymphocytic thyroiditis with acute exacerbations and the impact on your functioning is so severe, it would be nearly criminal for the GP not to do anything or just continue to shrug and go "Meh" without a course of treatment or a clear diagnostic pathway moving forward.

Okay, sounds like the derm is a good thing to ask about then. I've always taken topicals for pso but for yrs I've just been using non medical moisturizers. It's been more than a decade I've seen a derm though. I've heard good things about Otzela too bc there was a meta-analysis I read that said it doesn't up your cancer and infection risk.
I think the Wellbutrin is for depression or something like that but haven't seen a psychiatrist in over 10 yrs, but when I did he diagnosed me with clinical depression and OCD. My GP prescribes and manages psych meds.
I actually know about PML, only bc I have been trying to figure out what is causing my fatigue so I researched MS for a while. PML sounds terrifying. It's so shitty how many MS treatments can cause it bc it's like MS degeneration in hyperspeed.
The visual snow is the same whether moving or not and I've had it all my life, even when I was 2. It used to scare me when I was trying to sleep bc it's there whenever I'm conscious, even when my eyes are closed. But my mom said it was normal to get me to sleep so I just accepted it and it didn't bother me after that. I was diagnosed twice in school with NVLD by a neuropsych, which I think points to issues in some brain areas. It's a learning disability sometimes compared to Aspergers but I feel the visual processing issues a lot more than the autistic social problems.
My period was normal, seemed to last forever and really messed up my mental health for some reason. I think it lasted about a week usually, but turns out I had a micro-perforate hymen that I got removed surgically. I thought it was normal for a tampon to hurt like hell and that everyone experiences this.

The imaging you've had done rules out most things, but one that likely wouldn't have been picked up by any of those tests is adrenal insufficiency. Your symptoms are a good fit. Tremors, Heat Intolerance, Rapid Heartbeat (usually secondary to compensation for sudden low blood pressure), Fatigue, Depression, etc... Do you ever experience abdominal pain (not from a known cause), unusual nausea, poor concentration (not related to lack of sleep or other known cause)? These can be additional signs of adrenal insufficiency. If it's mild it could slip under the radar, appearing as a constellation of seemingly unrelated symptoms. It would most likely be worth mentioning to your doctor.

I assume they have checked your thyroid levels? Many of your symptoms can overlap with hypothyroidism, but overall adrenal insufficiency is a much better fit. There is a well known phenomenon in medicine where if one has an autoimmune disease, it is that much easier to develop another autoimmune condition. If is not uncommon for people with autoimmunity to have 2 or 3 distinct autoimmune conditions. Since you have psoriasis autoimmunity against the adrenal gland or thyroid are a much higher probability than they would be for the average person. Also, the autoimmune tests they have done are rather limited. RF & ANA would only be useful for a few specific conditions. A broader autoantibody panel may be more useful.

Serious question, how to remove burgers from ass? Status: urgent.

If it's actually in your ass, a colonoscopic extraction is probably the best bet. If you're talking about eating a burger, and the size of your ass got bigger, then just less calories and exercise. However, depending on the size of the ass, one may not want to do anything. What many women consider a problem regarding the magnitude of one's ass, many men would consider beneficial. Food for though (not for the ass).
 
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Yeeeeah, some recent developments have been real fun!

On Sunday I took a turn for the worse, started getting palpitations with chest pain, all my resting rates were between 110 and 124 bpm. Needless to say that I called an ambulance and the paramedics took me to hospital for observation after measuring bpms as high as 150 lmao. While I was in, my arms and my legs kept going numb, central chest pain, pain under ribs, just that same old malaise.

Spent six hours there, on a bed, hooked to an EKG for observation, resting bpm never went under 93 (average 114) until they eventually discharged me with a kidney infection. The theory was that the infection and my meds were tipping me over the edge, and I was stable enough to treat kidneys at home so now I'm waiting to see if it will go down after treatment. No idea what the thyroid was looking like, or inflammation levels (just got "your bloods were okay, there is no damage"), don't have access to those records either. They just said my resting rate kept spiking up and down for some reason.

7 days cefalexin, twice a day. If the bpm doesn't improve, go fix the dosage with my shrink. This smells like bullshit though - I have been on this dose for over 4 months now, and I have never had issues this bad. They're probably deflecting massively onto the shrink (who actually did his homework and checked my cardio beforehand).

I don't know what they checked exactly in the blood test, but they said the chest x-ray was clear, and there was no heart damage. I don't think they checked for hashimoto's ABs, even though I gave them all the info I gave you.

I'm having to check my pulse before I take my daily methylphenidate. My "no methyl" days don't seem to be that much better by comparison (93 vs higher).

How fucked am I, if I really can't get it under 90 bpm at rest?

I've cut all caffeine, am watching salt intake and physical exertion, have started supplements. I won't get to talk to my doctor before the 7th of March (and I bet she won't care about what's going on really).

In the meanwhile, how can I keep my resting rate as low as possible? I feel like NHS healthcare will actually kill me this year.

Sorry, I know it's a lot to ask but any tips would be welcome!
 
I'm glad to hear that you are generally ok at the moment. Nasty business having to go to the ED for pyelonephritis. I'm guessing it was a silent UTI, no symptoms?

I agree that its crap they are pushing it onto the psychiatrist and blaming the methylphenidate. The tachycardia was triggered in response to the pyelonephritis. Tachycardia in response to pyelonephritis is not surprising. It's actually a common symptom. Keflex is alright, I would have probably picked something different. If the culture comes back with resistance, they might call you in the next day or two and change antibiotics.

You mentioned previously "chronic inflammation LUTS symptoms"; The pyelonephritis is related in some way?

As far as your pulse rate, anything less than 100 is considered acceptable. Anything 100 or more is considered stage 1 tachycardia. Lowering pulse rate is not particularly easy, since its an autonomic function. Staying hydrated will lower your pulse rate, as will getting at least 8 hours of sleep. Sleep deprivation tends to cause higher pulse rates the following day. Stress is probably the biggest contributor. The best way most people I know manage their stress is through meditation, yoga, mindfulness (this one is kind of complex, fortunately there are plenty of resources on the web that can explain it far better than I can). Some people find going for a leisurely walk can help, especially through a park or a natural area. Unfortunately, that is about it.
 
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