Dudeman Claire wanted to fuck in Rev2 wasn't full off different viruses though, just got hit by Alex wesker in the neck with uroboros and was able to transform into a Uber mensch. Can't remember his name for the life of me, and the game wasn't that great, but it did show that someone who isn't wesker could use it without turning into mindless worm tendrils.
In RE5 the 2nd tendril monster you fight was a failed candidate for Oroboros. Funny enough we never see in RE5 what a
successful subject looks like so Wesker's plan looks more or less like a "kill everybody"-type plan (which it more or less is) rather than a "cull the weak, buff the strong"-type plan. I'm not sure if Wesker himself would even survive it. From my POV it just looks like he's controlling it through sheer force of will from being extremely pissed off + being a kitchen sink of viruses.
We got Alex Wesker and Neil Fisher in Revelations 2 as Ouroboros infectees who experienced a successful transformation, but it's a very loose use of "successful" given they both just went insane prior or during the process so it's not really clear if it was a success at all then. Alex was dual-infected with Ouro and Phobos and Fisher was
just Ouro, which looks like this:
(If everyone had Phobos in them though then you can argue we've
never seen what a successful Ouroboros transformation looks like. The insanity though can be chalked up to Phobos - a major L for your superhuman virus to make you insane on the other side, I guess Albert was the better sibling. Guy didn't even want to be a god but I could be wrong.)
The RE series isn't exactly high art so putting any sort of thought into it might be a waste, but it's still funny to consider the plausible outcome of Wesker succeeding at the end of RE5. A
prerequisite of
surviving an Ouroboros infection is facing "unspeakable horrors" and "coming out in one piece" i.e. surviving a near-death experience but don't let the fear cripple you i.e.
Anime bullshit.
I've put together the list of Terra Save members who are most suited for this round of trials. They all have had experience dealing with bioterror an viruses. Their psych evals came out with flying colors. They face some unspeakable horrors and came out in one piece, indicating a strong resistance to emotional trauma.
Test subjects could only be successful superhumans based on the levels of Norepinephrine hormones in their body, which required the person to be exposed to life-threatening events but not be overcome by fear.
Ouroboros would've basically left all the RE protagonists (including Sherry Birkin lmao) "fine" meaning Wesker would've turned everybody who has it out against him into ubermensch. I'm not even sure if he would even qualify as a candidate. Would his time in CVX count? Was he even truly under any threat during RE1 after the dogs? I would wanna see how angry he'd get in that scenario, it'd make his last moment in 5 look Bob Ross-tier by comparison.
I want D.C. Douglas back.