I stopped watching The Boys halfway through season 2. I think the last thing I saw was Stormfront going on a murder spree in a apartment complex while chasing someone. I loved season 1.
I gave up somewhere in the middle of season 3. The anti-right-wing political sperging was just too on-the-nose for me.
Other shows: The Great. I admit, I stayed with it for two seasons despite the absolutely cloying portrayal of Catherine the Great as an oh-so-special visionary leader/Pollyanna. This was the Russian Royal Court. There was no way for her to play that innocent and cute for that long. And there was somehow a "diverse" Russian court? Also, there was one meta-joke in the second season about America and Russia being great friends for a long time, which was a mask-off moment for the writers. Why did I stick with it? Because Nicholas Hoult is a genius comic actor, that's why.
Only Murders in the Building. Admittedly, it's been a hard watch since season 2 where they tried to keep propping up Carla Delevigne, not to mention the season 2 finale...we get it, folks, you're actors doing an extended improv skit. Nobody likes improv, and if it's a scene scripted to appear as improv, good Christ, show, sink lower. Season 3 is where I only begrudgingly finished the season. They introduced a fucking musical, and I didn't even need to consult reddit to hear the unrelenting squeeing of the fandom over that absolute dogshit "Pickwick Triplets" song.
I also gave up on Mr. Robot in Season 4. The whole resolution of the Dark Army's grudge against Dom was an unsatisfying fizzle and it kind of took the momentum out of an already flagging season for me.
And we can talk about Once Upon a Time for about three hours...