The majority of main Ferengi characters were played by Jewish actors. - Quark, Rom, Zek, Nog, and one of the two actresses to play Quark/Rom's mother, all seem to have a Jewish background.
Jeffery Combs- i.e. 'Acting' Grand Nagus Brunt, is really the only main (or at least semi-main) Ferengi character I've found who doesn't appear to have any Jewish heritage at all.
I couldn't say whether or not that is all a coincidence, because I didn't cast any of them... But let's be honest, the Ferengi were almost all Jewish stereotypes from the very beginning... Is it really such a coincidence that so many Ferengi actors are also Jewish?