"Gay tranny" is redundant. Tranny is a subtype of gay. Anyway, that would ruin TESVI for me, but honestly what I'm more worried about is it getting more generic and less creative. Yes, I still like Oblivion and Skyrim, but I noticed with each game they have fewer creatures unique to the series and more real-life animals and cliche fantasy creatures. It's entirely possible that the next game will be boring as fuck. You might only get to fight woodland critters, zombies, skeletons, and maybe dragons again. They might do something retarded like remove all traces of RPG stat building to "reach a wider audience" or turn treasure chests into real-money loot boxes. They might remove the magic and alchemy systems outright, or just simplify them to the point that they're useless. All of those things seem even more likely than trannies.
Although, they did make every single follower in Skyrim bisexual... maybe you're on to something.