So, even though I still find the whole they/them thing kinda cringe, DE at least explained it for Flare in that
he basically has what seems like a second personality inside of him. Basically, Warframes mostly take over the personality of someone and then Entrai uses strains of those Warframes to make Protoframes, resulting into a mix of the original Warframe and the Protoframe. Obviously, I'll still be calling Temple/Flare him, but at least it's more interesting than "I am a very special boy!"
Biotic Rounds is great, but Leaded Gas suffers from the problem that gas procs are a bit of a mess.