What are some major injuries that would make you kill yourself?

[Bubbly Sink]

Okay, let's say you're in a freak accident, or get a significant piece of your body mutilated or destroyed entirely. what injury like this would cause you to kill yourself or decide to not live anymore?

for me, if i lost my massive cock, i would certainly kill myself

 

[Tsurubami Senri]

i'd kill myself if i'd had dementia. having no hands/fingers would be sick cause you get to have these cool ass cybernetic arms and i can be cool , but it's a shame that it costs a lot.