More seriously, here's how I'd clean up 14 Branchland Court:
1. Hire a two/three tonne truck to carry waste in. Have a hazmat suit available (ebay, ~$150) in case of severe infestation, and to prevent disease.
2. Clear away the yard first. Work out, then move in.
3. Move all "intended survivors" out of the area. Chris, Barb, the dogs, the cats, etc.
4. Buy two "bug bombs" for each room, three for heavily cluttered rooms, release them. Let the gas do its work.
5. Begin shifting some of the stuff out of non-essential rooms, such as store rooms and the like. To prevent Barb's screeching harpy calls regarding throwing away her three year old used paper plates or whatever, I will ask her if she has used it within the last 12 months. If yes, it stays. If no, or is spoiled or damaged, or is only being used for Barb's nesting material, it goes. Anything with any value is assessed under the same criteria, and if discarded, is instead sold to a pawn shop for whatever they'll take it for.
6. Whenever an area is clean of junk, give it a floors, walls, ceiling hot mop with bleach and heavy, hospital grade disinfectant. Repeat as necessary.
7. Work inward, focusing on "utility" areas next, such as the kitchens, bathrooms, computer areas, walkways, etc. Employ the same techniques as earlier, and use the hazmat suit when filth/infestation becomes too strong. Employ bug bombs judiciously and without remorse.
8. Finally reach the more intimate areas such as bedrooms, cupboards, clothes areas and the like. Treat these with the same attitude.
9. Bug-bomb the ceiling, attic, etc. Sweep and clean.
10. Discard items that are past their 'expiry' date. Mattresses, bedsheets, towels, blankets, etc. Anything that's more than 10+ years old and not kept solely as a momento is thrown.
11. Clean and sanitize areas like the bathrooms, toilets, sinks and food preparation tools (oven, microwave, etc).
12. Completely empty cupboards, larders, food shelving, etc. Anything that has perishable goes in the bin, no ifs or buts.
13. Examine salvage prospects. Are the cars salvagable? Bob's record collection? The autism papers? Etc. What can we save, if anything.
14. Carefully watch and coach the 14 Branchland Court inhabitants, teaching them good life skills. Trash goes in the bin straight away. The bin is emptied whenever three quarters full, or on Sunday evening, every week, regardless of state. Empty even empty bags, to keep the behaviour as a habit.
15. Monitor occasionally once I'm satisfied that they're engaging in good habits.
Hopefully that would help.