Oceanic Pole of Inaccessibility, the location in the Pacific Ocean farthest from any land, aka "Point Nemo". Sometimes the International Space Station passes overhead (in space) and the astronauts are the closest people in the world. Also the distance from coastal waters, and the nature of nearby ocean currents, keeps nutrients out of the water, so there's no marine life nearby. Just vast, eerie nothingness. It's near the coordinates HP Lovecraft made up for his damned city R'lyeh.