Youtuber Twomad dead at 23

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Muudea Sedik -- a popular YouTuber who goes by Twomad online -- has died ... TMZ has learned.

Law enforcement sources tell us the internet personality -- who has millions of followers across his various YT channels and social pages -- was found unresponsive Tuesday night at his Los Angeles-area home ... this after somebody called in to ask for a welfare check.

We're told Twomad hadn't been heard from in several days by concerned parties -- and he even missed some appointments. As a result, the LADP was sent to check on him ... and that's when they found his body, although it's unclear how long he'd been in that state.

Our sources say there was drug paraphernalia found on the scene, and at this point ... we're told this is being investigated as a possible overdose. No foul play is suspected in the death.

Twomad had caused concern among his fanbase in recent weeks -- including some strange, one-off tweets he was posting last week ... not to mention a bunch of photos of firearms.

The guy was an interesting character ... in addition to skits, gaming commentary, and live streams, he was just very into internet culture -- and had a massive fan base. Like we said, millions of followers ... but his videos would also get a significant number of views.

One meme, in particular, that he's credited with is the one called "Goodnight Girl, I'll See You Tomorrow." It features a shirtless Twomad walking up to the camera and telling some imaginary chick that he'll see her tomorrow ... only to slip and fall in cartoonish fashion.

He also made a splash by once collaborating with OnlyFans model Belle Delphine.

Twomad was embroiled in controversy of late -- and he seems to have been off the radar in recent months when it came to his content creation. His last video across all 3 of his channels was 5 months ago ... and he certainly seemed to be in good spirits in it.

He was only 23.

RIP
 
Also, for anyone that read the Community Happenings post, Mitragynine (which represents the active/functional moiety [chemical] in Kratom) is NOT approved nor proven safe or effective to any reasonable degree of certainty by SAMHSA, NIH, FDA, DEA, or any other federal or state agency in America, nor the WHO, EMA, MHRA, or TGA in the rest of the world for the treatment of anything, let alone Opiate Use Disorder (which is the official medical term, at least in the US, for opiate abuse/misuse). The scientific and medical understanding of Mitragynine, its effects, uses, adverse effects, interactions with medications and other non-prescriptions treatments are all very nascent and quite limited.

All the deaths involving Kratom have involved it along with other substances, indicating that the interactions between it and other substances is currently poorly understood and the risks it poses, alone and in combination, are largely unknown.

TL;DR, We don't know much of anything about Kratom (Mitragynine) at this point. Don't be retarded.
you say this like kratom is something that is some kind of unknown factor when it's a drug that joe rogan has been talking about for at least ten years at this point with a history of indigenous consumption. the medical establishment controls the entire opiate supply chain. if they give the official rubber stamp to treat opiate dependence with something that you can buy over the counter, they would be undermining the status quo they have so carefully built.
 
you say this like kratom is something that is some kind of unknown factor when it's a drug that joe rogan has been talking about for at least ten years at this point with a history of indigenous consumption. the medical establishment controls the entire opiate supply chain. if they give the official rubber stamp to treat opiate dependence with something that you can buy over the counter, they would be undermining the status quo they have so carefully built.
This is true, kratom has been heavily lobbied against by pharma companies for over a decade. They have more or less given up the fight now, but they fought very hard with a disinformation campaign that included polysubstance overdoses as justification for banning kratom, and it worked in a few states. There are some famous cases of parents, I think one was in Florida especially, that went around on a campaign to ban it because it was present in their child's system at the time of death. Obviously, if one looked at the cases for even a few minutes, it was not mitragynine that caused the death, but polysubstance overdose and the parents are coping and in denial.

Mitragynine has been studied a decent amount, but the results are not what the pharma companies were looking for, so the bulk of research is wilfully ignored and people still commonly believe there is little or no rssearch on it. They even tried to make a synthetic mitragynine so they could patent it, ban the natural version, and make a fortune selling the synthetic, but I'm not sure where that is now, it would be an interesting rabbit hole to follow.

To date, I don't think there is a single death attributed to mitragynine alone. Serious allergic reacions are possible, but that can also happen with plants like coffee (the same tree family as Kratom) or rubber or virtually anything else. It has, however, shown great promise as a treatment for opiate/opioid addiction as it has little or sometimes even no physical and mental withdrawal symptoms because of the unique way it affects opioid receptors in the brain, which was also used as justification for scheduling, but even cheese works on these receptors soo....

Edit: Individuals ignorant of the potentiating effect of kratom could be a factor in the polysubstance overdoses, but banning it by this logic would also force you to ban grapefruit juice.
 
but the results are not what the pharma companies were looking for, so the bulk of research is wilfully ignored and people still commonly believe there is little or no rssearch on it. They even tried to make a synthetic mitragynine so they could patent it, ban the natural version, and make a fortune selling the synthetic, but I'm not sure where that is now, it would be an interesting rabbit hole to follow.
pharmaceutical companies make money by doing research on a class of chemicals and the complexes that they create. drugs like opiates, beta blockers, ssris, and antipsychotics are pretty much just rearrangements of a core structure that influence metabolism and hormone binding. with kratom the chemical complex that gives the plant its effect isn't something they can just rearrange without it losing its effects, and you also need to dose orders of magnitude more to get significantly less of an effect, even with the synthetic 7-hydroxy mytragine stuff.

its a drug by anyone's understanding of the word but its not a drug that fits into the very specific scheme they've created to dose medication because its not very potent and obviously addictive - but less so than the habit people are trying to kick with it
 
pharmaceutical companies make money by doing research on a class of chemicals and the complexes that they create. drugs like opiates, beta blockers, ssris, and antipsychotics are pretty much just rearrangements of a core structure that influence metabolism and hormone binding. with kratom the chemical complex that gives the plant its effect isn't something they can just rearrange without it losing its effects, and you also need to dose orders of magnitude more to get significantly less of an effect, even with the synthetic 7-hydroxy mytragine stuff.

its a drug by anyone's understanding of the word but its not a drug that fits into the very specific scheme they've created to dose medication because its not very potent and obviously addictive - but less so than the habit people are trying to kick with it
Right, the effects of the plants aren't exclusive to mitragynine or 7-OH (being the main alkaloids acting on the μ and other opioid receptors). There are a lot of active alkaloids that act together to create the totality of the effect (which is very mild with some people barely noticing a "high" at all). That is why different strains (red, white, green, etc.) have somewhat different effects.

I can't remember the exact research that was being done on creating patentable versions of these alkaloids for medical purposes, as it was almost 10 years ago that I last thought about this. A quick search found this patent: US20180134708A1 though I haven't looked into that one.

That being said, I don't think it is immoral to create novel drugs using naturally occuring substances as a basis, but it is duplicitous and immoral to try to modify the most active compounds in a drug, patent it for financial gain and control, and lobby to schedule the naturally occuring substance so that you can profit off the patent for something you will not know the true effects of for decades, while the effects of the plant are well known and have a long history. This happened with opiates/opioids (Sackler), cannabinoids, and more. It's a big racket and has been for most of human history, just slightly more complex now.

For example: Eli Lily's Propoxyphene (the heart annhilator). Creating synthetics, in many cases, is high risk for the consumer, and high profit/little risk for the researcher and manufacturer.
 
It has, however, shown great promise as a treatment for opiate/opioid addiction as it has little or sometimes even no physical and mental withdrawal symptoms because of the unique way it affects opioid receptors in the brain, which was also used as justification for scheduling, but even cheese works on these receptors soo....
It would be a really bad idea to use something to treat opi* addictions that can cause fatal overdoses when combined with those very substances, since people into those have a huge tendency to relapse. They really ought to eliminate that possibility before ever using it for that purpose.

They won't, for obvious reasons, but they should.
 
As someone who self medicates daily with kratom (a safer alternative to basically everything else I've done in my life), I say this is total horseshit. Maybe at tiny itty bitty doses, but that can be said for any drug.
Idk, compared to the withdrawals from opiates, other opioids, caffeine, nicotine, benzos, or most other drugs, kratom withdrawals barely compare. You might get flu-like symptoms for a day or two, and have a strong mental compulsion to continue the habit, but not much more than other long-held habits. The half-life is not that long, but depends on body fat, genetics, metabolism, etc.

I'm not advocating people to do it, but it's surely one of the safer things out there.

As for the potentiation... if you're a drug user, Rx or not, and not aware of contraindications to the drugs you're using, you are absolutely retarded.
 
Pretty sad, pretty common.
Classic junkie death, happens to so many opiate/opioid addicts who are fresh out of rehab and relapse. Not too bad of a way to die, most likely just nodded off and that was it. Despite not being a hardcore follower of TwoMad i found him to be one of the more funny zoomer content creators. To add, Jameskii is one disgraceful homo, behaving more womanly than your average Cluster B wreck.
As for the potentiation... if you're a drug user, Rx or not, and not aware of contraindications to the drugs you're using, you are absolutely retarded.
100% truth, it's like the absolute minimum you should be aware of when you get into hard drugs.
 
Is he still dead?
yes and Jameskii is a fucking coward.
For someone whose entire youtube career was built upon interacting with kids and trolling them to tears, he was unreasonably preachy. I hope he doesn't have any skeleton in the wardrobe, because a thread on him would be one of the saddest. But really, his series of tweets are still enraging to this day. Why did he waited until 2Mad die before speaking out against him? it's not that a 23 years old retard would've been much of a threat to him, especially with the decline he faced because of Fentanyl.
I'm glad people come back to this thread to necro because I think it should be known what Jameskii did and what he got away with saying. The more people that read this thread the better.
Yeah, I really hope more people start digging out his past, because after his return, jameskii has been sounding more preachy and annoying than usual. I used to follow him before the twomad drama, and the difference between then and now is like night and day. Maybe I'm just remembering things wrong, but Jameskii has turned from a fun troll to an insufferable asshole.
 
yes and Jameskii is a fucking coward.
For someone whose entire youtube career was built upon interacting with kids and trolling them to tears, he was unreasonably preachy. I hope he doesn't have any skeleton in the wardrobe, because a thread on him would be one of the saddest. But really, his series of tweets are still enraging to this day. Why did he waited until 2Mad die before speaking out against him? it's not that a 23 years old retard would've been much of a threat to him, especially with the decline he faced because of Fentanyl.

Yeah, I really hope more people start digging out his past, because after his return, jameskii has been sounding more preachy and annoying than usual. I used to follow him before the twomad drama, and the difference between then and now is like night and day. Maybe I'm just remembering things wrong, but Jameskii has turned from a fun troll to an insufferable asshole.
There's already a thread for the russian faggot https://kiwifarms.st/threads/jameskii-igor-kisly-priemsky-kiisliy-james-swire-prime-comas.183405/. I hope at some point more people will see what he actually did to twomad and make him accountable for this shit.
 
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