I've mentioned it a few times but, the odds of the game don't matter. The multis don't matter. It's a "sweepstakes". Once you place your bet, it checks if you won, how much, and then displays some combination of game-relevant shit to add up to that much. That's why all the highest multiplier wins are such small amounts. All the RTP and odds of the game don't matter. Slots, keno, whatever, it's all coming from the same thing. It's a massive drawing that is being played by everyone on the site. 20% of the entrants into a given drawing will win, 80% will lose, and Stake takes some amount off the top.
Edit: According to Stake's website, this isn't how it works. I don't believe them, but they claim it is random number generation.