- Joined
- Mar 11, 2016
Any study of puberty blockers is going to have at least two very large obstacles to clear: The sample will be small, and it will have any number of comorbidities. The former means that the error bars will be huge, and the latter means they can't tease out bone damage from blockers from bone damage from anorexia (common comorbidity). If HRT is as much of a Wild West as SRS, there could be a third confounding factor in the form of different doctors having very different treatments for the same condition.I could be wrong, but I thought there was quite substantial evidence that puberty blockers wreck your skeleton.
It's the same reason evidence was low quality across the board; anything even close to a large, well controlled sample just does not exist in gender medicine so no amount of doing more studies, or running more statistical tests on the results we do have, will change the conclusion of 'no statistically significant change'.