Yeah, not gonna happen, one of the main reasons why bronies were a thing in the first place, its because the early 2010s were a different time, social media was still relatively young and the concept of adults latching onto kids shows was completely new, that's why bronies got a lot of media coverage back in the day, they were all over the news and social media, everyone wanted to be part of that trend, wanted the attention, wanted to feel special and unique, by being an adult liking a show meant for little girls
But even with all of that attention, bronies reached their peak in 2012 and went into life support in 2014, and by 2019 they are barely still active, Hasbro will try everything to make the brony phenomenon happen again, i can imagine every single episode of Gen 5 being nothing but 22 minutes of brony memes, but i don't se it getting as big as Gen 4 did, adults into children shows were totally unheard of in 2010, but now, it is almost normal, you can see everywhere, a bunch of 30 year olds crying in social media because the last episode of Voltron or Steven Universe destroyed them emotionally, adults who are into kids shows are no longer newsworthy, and even then, if the new show manages to get some popularity, at the very worst its going to be the Rick and Morty fandom again, loud and obnoxious for a couple of years, and then it will fall into irrelevancy like everything else