- Joined
- Sep 17, 2019
Oh he's definitely going full DFE. He was even bragging about it in chat yesterday (kudos to @Spedestrian for grabbing this):more shows up in the results, but he's gone either gone full DFE or he's renaming accounts
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Oh he's definitely going full DFE. He was even bragging about it in chat yesterday (kudos to @Spedestrian for grabbing this):more shows up in the results, but he's gone either gone full DFE or he's renaming accounts
“I too have an incredible cock-thirst” —— @Drain Todger
as an aside, this site exists and now i want coronachan to kiss me off this planet
Dave, Can I call you Dave? You did a dumb dumb. Next time please concider not doing something stupid.
Where has the claim the Virus has the same receptor paths as the HIV virus come from? I keep seeing this pop up but I dont know how true it is or why it's even a rumor.
The AT1 receptor mediates the major cardiovascular effects of angiotensin II. Effects include vasoconstriction, aldosterone synthesis and secretion, increased vasopressin secretion, cardiac hypertrophy, augmentation of peripheral noradrenergic activity, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular matrix formation.
as an aside, this site exists and now i want coronachan to kiss me off this planet
You got doxed as a complete and utter sperg that fantasizes about fucking horses and who is too retarded to do any research or get when people are done with you given you can't sort information by relevence and YOU'RE STILL DOOMPOSTING HERE.Duly noted.
Now, let's get down to brass tacks.
I predict that sometime in Mid-April or perhaps May, if we don't implement full isolation between now and then, we'll see suspension of Posse Comitatus and the use of US Army and Marines to enforce quarantines with manpower the National Guard cannot match.
![]()
Use of Military Forces in the COVID-19 Emergency
As the effects of COVID-19 are increasingly felt around the United States, many officials and commentators have asked what role the U.S. military might play as part of the response. Several state governors have already called up elements of the National Guard as part of their emergency measures...www.csis.org
![]()
Will coronavirus lead to martial law?
As more states call up National Guard units to aid with the spread of coronavirus, some are concerned about martial law.www.militarytimes.com
It is possible it could be avoided, if everyone just stays home for the next month or so and stops going out and getting sick. We'll see.
Nope. It uses the same entry receptor as SARS: ACE2.
ACE2 stands for Angiotensin Converting Enzyme 2.
![]()
Angiotensin-converting enzyme 2 - Wikipedia
en.wikipedia.org
Normally, Angiotensin II is catalyzed by ACE2 and converts into Angiotensin 1-7.
![]()
Angiotensin - Wikipedia
en.wikipedia.org
![]()
Angiotensin (1-7) - Wikipedia
en.wikipedia.org
Angiotensin 1-7 is a Mas receptor agonist.
![]()
MAS1 - Wikipedia
en.wikipedia.org
This normal route, Ang II > ACE2 > Ang 1-7 > MasR is anti-inflammatory and vasodilatory.
Now, what happens when the virus uses up ACE2 as its entry receptor? Well, instead, Ang II builds up and activates AT1R.
![]()
Angiotensin II receptor type 1 - Wikipedia
en.wikipedia.org
This has the opposite effect. Vasoconstriction, inflammation, electrolytic imbalance, and so on.
Because of the virus using ACE2 as its entry receptor, the renin-angiotensin-aldosterone system is thrown out of balance.
Do you know what this does? This sends inflammatory cytokines into your tissues, it can aggravate hypertension, oh, and it can also cause hypokalemia, or low blood potassium:
A new potential risk of COVID-19: Sudden cardiac death | MDLinx
Clinical trials have begun for potential COVID-19 treatments.www.mdlinx.com
![]()
Covid-19 Research Updates: Chinese Study Reveals That Hypokalemia Present In Almost All Covid-19 Patients - Thailand Medical News
Covid-19 Research: A new research study by researchers from Wenzhou Medical University in Zhejiang province lead by Dr Don Chen revealed that almost all Covid-19 patients exhibited hypokalemia and that supplementation with potassium ions was one of the many factors that assisted in their...www.thailandmedical.news
Normally, the RAAS system uses a delicate dance of hormones to make sure your blood pressure and intracellular levels of sodium and potassium are correct. COVID-19 is an enormous monkey wrench thrown into that entire process, and that's just one of the ways it causes damage.
The other way it causes damage, other than helping bacteria infect you, is mostly hypoxemia from the pneumonia and ARDS. The low blood O2 saturation causes multiple organ damage on top of the inflammation. Your organs need oxygenated blood to stay alive, to put it quite simply.
The claim of the virus having an HIV-like nature comes from the fact that SARS-CoV-2 has a unique mutation where the S protein has furin cleavage sites. These articles explain it quite well:
Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein
The spike glycoprotein of the newly emerged SARS-CoV-2 contains a potential cleavage site for furin proteases, an observation with implications for the zoonotic origin of the virus and its epidemic spread in China.www.virology.ws
![]()
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
In 2019, a new coronavirus (2019-nCoV) infecting Humans has emerged in Wuhan, China. Its genome has been sequenced and the genomic information promptl…www.sciencedirect.com
![]()
Coronavirus more likely than Sars to bond to human cells, scientists say
Research by team from Nankai University shows new virus has mutated gene similar to those found in HIV and Ebola.www.scmp.com
![]()
Furin - Wikipedia
en.wikipedia.org
This property makes it far more infectious than SARS. In fact, the defining aspect of SARS-CoV-2 is that it is basically a form of SARS with very efficient spikes that enable rapid human-to-human transmission.
I’m Train Dodger. I don’t need a big, long-winded bio. You don’t need to know anything about me. I’m just about the most horrible person who ever lived. I’m not going to glitter-bomb you with 16-year-old schoolgirl nonsense. I’m not going to tell you all about my OCs and how speshul they are. I’m not going to tell you about my litany of mental issues and how you need to kiss my ass because of them. Just read the damn stories and comment if you like ’em. Or don’t, and save your sanity.
When I was 11, I wrote cringy Powerpuff Girls script-fics. When I was 16, I wrote a godawful Halo fic that was only notable because I somehow cranked out a 10-kiloword chapter of it in a day, but it was all trash anyway. No, you can’t read it. I deleted all that garbage. Now that I’m going on my thirties, I write very, very depressing things that are precision-engineered to make you nauseous and choked-up. Welcome to the wasteland, suckas.
My Fimfiction profile: https:///user/62643/TrainDodger
Duly noted.
Now, let's get down to brass tacks.
I predict that sometime in Mid-April or perhaps May, if we don't implement full isolation between now and then, we'll see suspension of Posse Comitatus and the use of US Army and Marines to enforce quarantines with manpower the National Guard cannot match.
![]()
Use of Military Forces in the COVID-19 Emergency
As the effects of COVID-19 are increasingly felt around the United States, many officials and commentators have asked what role the U.S. military might play as part of the response. Several state governors have already called up elements of the National Guard as part of their emergency measures...www.csis.org
![]()
Will coronavirus lead to martial law?
As more states call up National Guard units to aid with the spread of coronavirus, some are concerned about martial law.www.militarytimes.com
It is possible it could be avoided, if everyone just stays home for the next month or so and stops going out and getting sick. We'll see.
Nope. It uses the same entry receptor as SARS: ACE2.
ACE2 stands for Angiotensin Converting Enzyme 2.
![]()
Angiotensin-converting enzyme 2 - Wikipedia
en.wikipedia.org
Normally, Angiotensin II is catalyzed by ACE2 and converts into Angiotensin 1-7.
![]()
Angiotensin - Wikipedia
en.wikipedia.org
![]()
Angiotensin (1-7) - Wikipedia
en.wikipedia.org
Angiotensin 1-7 is a Mas receptor agonist.
![]()
MAS1 - Wikipedia
en.wikipedia.org
This normal route, Ang II > ACE2 > Ang 1-7 > MasR is anti-inflammatory and vasodilatory.
Now, what happens when the virus uses up ACE2 as its entry receptor? Well, instead, Ang II builds up and activates AT1R.
![]()
Angiotensin II receptor type 1 - Wikipedia
en.wikipedia.org
This has the opposite effect. Vasoconstriction, inflammation, electrolytic imbalance, and so on.
Because of the virus using ACE2 as its entry receptor, the renin-angiotensin-aldosterone system is thrown out of balance.
Do you know what this does? This sends inflammatory cytokines into your tissues, it can aggravate hypertension, oh, and it can also cause hypokalemia, or low blood potassium:
A new potential risk of COVID-19: Sudden cardiac death | MDLinx
Clinical trials have begun for potential COVID-19 treatments.www.mdlinx.com
![]()
Covid-19 Research Updates: Chinese Study Reveals That Hypokalemia Present In Almost All Covid-19 Patients - Thailand Medical News
Covid-19 Research: A new research study by researchers from Wenzhou Medical University in Zhejiang province lead by Dr Don Chen revealed that almost all Covid-19 patients exhibited hypokalemia and that supplementation with potassium ions was one of the many factors that assisted in their...www.thailandmedical.news
Normally, the RAAS system uses a delicate dance of hormones to make sure your blood pressure and intracellular levels of sodium and potassium are correct. COVID-19 is an enormous monkey wrench thrown into that entire process, and that's just one of the ways it causes damage.
The other way it causes damage, other than helping bacteria infect you, is mostly hypoxemia from the pneumonia and ARDS. The low blood O2 saturation causes multiple organ damage on top of the inflammation. Your organs need oxygenated blood to stay alive, to put it quite simply.
The claim of the virus having an HIV-like nature comes from the fact that SARS-CoV-2 has a unique mutation where the S protein has furin cleavage sites. These articles explain it quite well:
Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein
The spike glycoprotein of the newly emerged SARS-CoV-2 contains a potential cleavage site for furin proteases, an observation with implications for the zoonotic origin of the virus and its epidemic spread in China.www.virology.ws
![]()
The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
In 2019, a new coronavirus (2019-nCoV) infecting Humans has emerged in Wuhan, China. Its genome has been sequenced and the genomic information promptl…www.sciencedirect.com
![]()
Coronavirus more likely than Sars to bond to human cells, scientists say
Research by team from Nankai University shows new virus has mutated gene similar to those found in HIV and Ebola.www.scmp.com
![]()
Furin - Wikipedia
en.wikipedia.org
This property makes it far more infectious than SARS. In fact, the defining aspect of SARS-CoV-2 is that it is basically a form of SARS with very efficient spikes that enable rapid human-to-human transmission.
Are you expecting any kiwi to take you seriously at this point? Your optimism knows no bounds.Now, let's get down to brass tacks.
It's amazing right? Absolutely heroic levels of autism. Who said nothing good came out of this pandemic?You got doxed as a complete and utter sperg that fantasizes about fucking horses and who is too exceptional to do any research or get when people are done with you given you can't sort information by relevence and YOU'RE STILL DOOMPOSTING HERE.
Amazing. Absolutely amazing.