Wuhan Coronavirus: Megathread - Got too big

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Outside China

6,294,078 confirmed / 375,615 dead / 2,650,127 recovered

6080654 / 367349 / 2561680 two days ago

USA

1,831,821 confirmed / 106,180 dead / 463,868 recovered JohnHopkins
1,835,147 confirmed / 106,418 dead / 645,974 recovered Infection2020

1789368 / 104357 / 444758 two days ago JohnHopkins
1795878 / 105169 / 599867 two days ago Infection2020

Spain

239,932 recovered / 27,127 dead / 150,376 recovered

239479 / 27127 / 150376 two days ago

Italy

233,515 recovered / 33,530 dead / 160,092 recovered

232997 / 33415 / 157507 two days ago

France

188,450 confirmed / 28,943 dead / 68930 recovered

189009 / 28805 / 68473 two days ago

Germany

183,879 confirmed / 8,563 dead / 166,609 recovered

183410 / 8540 / 165352 two days ago


John Hopkins France confirmed numbers wrong.

Mexico cracks 10k dead with:
97,326 confirmed / 10,637 dead / 69,749 recovered
 
"If we had known what we know today"... as if there weren't people who tried to warn him and the other responsible multiple times without them wanting to listen, only for the critics to turn out to be right :roll: http://archive.md/8EIoc
Tegnell: More measures were needed

Sweden should have taken more measures against the corona virus right from the start. This is stated by state epidemiologist Anders Tegnell in an interview with Ekot.
- Should we encounter the same disease, with exactly what we know about it today, I think we would land in doing midway between what Sweden did and what the rest of the world did.

Somewhere in between?

- Yes, I think there is potential for improvement in what we have done in Sweden, quite clearly. And it would be good to know more exactly what to shut down to prevent the spread of infection better.

Unlike many other countries in Europe, Sweden chose a strategy that would limit the spread of the corona virus, while protecting risk groups. Don't push it back as much as possible.

The strategy has allowed us to have a more open society.

But it has also caused the spread of infection in society, albeit at a lower level and even if the deaths have dropped, nearly 50 people still die in Sweden a day. And a total of more than 4,000 people have died in Sweden after being infected by the new corona virus.

State epidemiologist Anders Tegnell has constantly argued that Sweden had the most sustainable strategy, but he is now also self-critical. It is among other things the high death tolls that got Anders Tegnell to think about.

Have too many people died too soon in Sweden, so far?

- Yes absolutely.

And had it been possible to do something about it?

- Yes, that is what we might consider in the future if there was any way to prevent it.

But while he would have liked to use more measures that pushed back the corona virus faster and longer, he is still unsure of what measures Sweden should have introduced. Or if it is just that we should have introduced all the measures at once instead of step by step.

- Actually, all countries have thrown everything in right away. Sweden is one of the few countries that has worked up a stop more and more. All other countries started with a lot of things at once, and the problem with that is that you don't really know which of the measures you have taken has the best effect. Maybe we know that now when you start taking action off one by one, and then maybe we get some kind of lesson about what else, besides what we did, you could do without driving the total shutdown.
The Swedish strategy is clearly to criticize other countries' strategies non stop while praising the superiority of yours but not be able to explain what they did wrong and right and also be incapable to explain what you did wrong and right because the whole thing is run by a bunch of headless chickens. :story:

Edit: Britbong article http://archive.is/80YoK
Swedish expert admits country should have had tighter coronavirus controls
Shift comes as Stockholm promises a commission to investigate approach to pandemic

The architect of Sweden’s controversial lighter lockdown policy for dealing with coronavirus has for the first time conceded the Scandinavian country should have imposed more restrictions to avoid having such a high death toll.

Anders Tegnell, Sweden’s state epidemiologist, agreed with the interviewer on Sveriges Radio that too many people had died in the country.

“If we would encounter the same disease, with exactly what we know about it today, I think we would land midway between what Sweden did and what the rest of the world did,” Mr Tegnell said in the interview broadcast on Wednesday morning.

Mr Tegnell’s admission is striking as for months he has criticised other countries’ lockdowns and insisted that Sweden’s approach was more sustainable despite heavy international scrutiny of its stubbornly high death toll.

Sweden’s centre-left government on Monday said it would appoint a commission to investigate the country’s approach to coronavirus before the summer, bowing to pressure from opposition politicians.

The public mood in Sweden appears to have shifted somewhat since neighbouring Norway and Denmark last week opened their borders to each other but not their close neighbour. Sweden has reported a much higher death toll relative to its population size than Norway.

Mr Tegnell said in the interview: “There is quite obviously a potential for improvement in what we have done in Sweden. It would be good to know exactly what to close down to better prevent the spread of the virus.”

He added that because nearly all other European countries locked down suddenly it was difficult to know which measures worked best. Sweden kept its schools for under 16s open, a policy that health authorities in Norway and Denmark now think wise. It also kept its borders open to European visitors and relied on public co-operation rather than formal rules for social distancing.

The Swedish public has strongly backed Mr Tegnell’s approach but politicians and diplomats said they sensed a change in mood in recent days.

“Every week that goes by, the public discussion grows about the measures that have been taken or not,” said Hans Wallmark, a centre-right opposition MP.

He said the public were dismayed by three things: the high death toll in care homes that makes many people “almost ashamed”; the failure to deliver a mass testing scheme for Covid-19; and the closed borders for Swedes. “All those things are leading to a more critical discussion among Swedes,” he added.

A former senior Swedish diplomat said: “We have had a very deep and intimate Nordic co-operation in a great many aspects. People are not very happy that our close Nordic neighbours are closing their borders to us, and they are feeling worried and concerned that our strategy seems to have led to the worst kind of results.”

Sweden's diplomatic isolation in the Nordics has coincided with a more critical tone from Swedish media.

“In the short run, it might be fair to say that Sweden is isolated. The general tone of people and the press is that they are more critical. The general public is waking up to the fact that neighbouring countries and others are critical,” said a European diplomat in Stockholm.

Sweden has had 4,468 Covid-19 deaths whereas Denmark and Norway, each with about half their neighbour’s population, have had 580 and 237, respectively. Both Copenhagen and Oslo said the higher infection rate in Sweden was behind their decision not to open their borders to Swedes.

Carl Bildt, the former centre-right Swedish prime minister, said: “It is disturbing that Swedes are considered somewhat more unsafe than others in our part of Europe.” He pointed to particular anger in the southern region of Skane, which is connected to Denmark by the Oresund bridge from Malmo to Copenhagen and where the infection rate is far lower than in Stockholm.

“I guess they feel to be punished for policies decided in a faraway capital up north,” Mr Bildt added.

Sweden has open borders to all EU and Norwegian citizens, and thousands of Danes streamed over the bridge to visit their summer cottages in Skane this Whitsun weekend. On Tuesday, Danish police reported 3km tailbacks on the bridge as Danes queued to return home.

Mette Frederiksen, Denmark’s centre-left prime minister, has said that her country is in talks to look at opening up to individual Swedish regions such as Skane, while Oslo is also holding talks with Stockholm about a potential opening up.

Mr Wallmark, whose constituency is in Skane, said that Swedes in border regions take the closed frontiers personally.

“The risk is that it feeds a feeling that we need countermeasures against them,” he said. “People are saying, especially in my constituency, ‘If we can’t go to Copenhagen, then why can the Danes come to Malmo?’ In the long run, it’s a really bad sentiment that goes against deepening co-operation and trust in the Nordic region.”

The centre-left government in Stockholm has been left weakened by the Norwegian and Danish decisions after weeks of pleading for Nordic co-operation in opening borders. But the direct effect may be limited as Sweden’s official advice is to avoid foreign travel or journeys of more than one or two hours.

Mikael Damberg, Sweden’s interior minister, told public broadcaster SVT that although Stockholm was hard hit, the border regions with Norway or Denmark had lower infection rates than on the other side. “There are pretty weak arguments for having closed borders, as it looks now,” he said.

Italy’s ambassador to Stockholm became only the latest European diplomat to express displeasure at the tendency of Mr Tegnell to compare Sweden favourably with other countries — in this case by saying it should “manage this better” than Rome.

“Tegnell has been very high-handed in his comments about other countries, and that’s not endeared him to others,” said the former Swedish diplomat, who also pointed out that his country appeared isolated in the EU when it had been one of the few countries not to send any help to Italy at the height of the pandemic.

Along with Denmark, the Netherlands and Austria, the other members of the so-called Frugal Four, Sweden is under pressure over its opposition to a €750bn recovery fund announced by the European Commission last week.

Andreas Hatzigeorgiou, head of the Stockholm Chamber of Commerce, said he was worried that in the long term, measures to combat coronavirus would lead to “protectionism or even isolationism”. He added: “Cross-border mobility, free trade and human exchange may have contributed to the spread of Covid-19, but an economic reboot will require opening up to foreign trade and international visitors sooner rather than later.”

Long article on the elderly eugenics boogaloo
The unknown curve shows how older people are prioritized away

The proportion of elderly people who received intensive care for covid-19 decreased sharply when the situation was at its worst, according to SvD's survey. At the same time, lack of medical skills has exacerbated the corona crisis in the elderly. Are we providing our oldest second-class care in Sweden?

The press conference on Saturday, March 21, does not differ significantly from what listeners and television viewers around the country have already begun to get used to. A couple of weeks after the sports holiday, a total of 17 deaths in covid-19 have been reported in Sweden and state epidemiologist Anders Tegnell is again reporting the strategy.
- We are continuing to plan out the curve so that we do not go beyond the limit for the number of medical places.
Two months later, the death toll has passed 4,000, but the curve on the number of intensive care patients has been flat and has always been below the ceiling for maximum care capacity. It is described as a success.
At the same time, the image of reports of elderly people who have not received the qualified care they are entitled to is clouded. The Inspectorate for Health and Care, Ivo, reports at the end of May that since March they have received 3,000 reports of risks and found serious deficiencies in every ten operations.
Several relatives whom SvD has been in contact with in recent months are concerned about whether their parents or partners receive the qualified care they are entitled to.
One woman says that her 90-year-old husband had a high fever at an accommodation where infection occurred. He was judged to be a corona patient and no further investigation was done. But the wife, who herself worked in health care, protested and demanded that a urine sample be taken.
- It showed that he had a urinary tract infection and after he got antibiotics he quickly got better. I can't stop thinking about how it would have been if I hadn't gone in, she says.

It and similar stories raise the question of whether the Public Health Authority's curve has been leveled out to keep the infection at bay - or whether it is because not all needy residents have received a proper medical assessment and access to intensive care.
When SvD, via the Swedish Intensive Care Register, Sir, maps the number of intensive care services in all of Sweden's health care regions since the outbreak took off, another curve emerges.
It shows that the proportion of people over 70 who have received intensive care started at a high level and then dropped when the outbreak reached its peak.
The least chance of getting intensive care was the elderly who became ill during Easter week and the rest of April. In Stockholm, every other intensive care corona patient was over 70 years from the beginning, a proportion that on April 21 had dropped to 11 percent, which SVT previously revealed. Following anonymous tips on cases where the elderly are prioritized away, the Inspectorate for Health and Care initiated an investigation that is still ongoing.
The SvD's review now shows that the downturn in Stockholm was more severe and lasted longer than previously reported. It also shows that the proportion of older covid-19 patients receiving intensive care again increased as the influx of the total number of new patients decreased in May.

So have the elderly been used as accordions to cope with the capacity for intensive care?
- If it is true that the elderly are chosen from intensive care for reasons other than medical, then it is very serious. Then you have made mistakes, which should prove in the review that Ivo is doing. But I have a hard time believing that this would have happened during the pandemic because we have so far had no shortage of IVA sites in Stockholm, says the Stockholm Regional Health Council, Anna Starbrink (L).
For those who are older than 70 years and ill in covid-19 during the spring, the opportunities for access to intensive care vary greatly depending on where in the country you live.
We clearly find the highest proportion of elderly people in intensive care in the Southern Healthcare region. When the entire period up to week 21 is summed up, it turns out that the proportion of elderly people receiving intensive care there has been twice as high as in Stockholm: 32.4 percent versus 16.3 percent.

Sweden also stands out in an international comparison.
According to the Norwegian Intensive Care Register, 30 percent of those enrolled have been older than 70 years. This can be compared with the Swedish national average during the entire outbreak of 21 percent.
In Denmark, the corresponding proportion is 49 percent. Finland is at the same level as Sweden, but at the same time has far fewer sick and deceased in total.

Johnny Hillgren, chairman of the Swedish Intensive Care Register, also says that he cannot judge whether the elderly have been used as accordion to avoid overcrowding, but this is not something he recognizes from his own activities. At the same time, he confirms that the statistics from the Nordic registers are comparable to the Swedish one.
- The criteria for the selection of data do not differ between the Nordic countries. In other parts of Europe, there may be differences that make it difficult to draw certain conclusions, says Johnny Hillgren, who is currently the head of operations for anesthesia in the Gävleborg Region.
He believes that future investigations may show what the differences between the Nordic countries are due to.
The hard sorting in intensive care is not the whole explanation for the fact that so many elderly people died in covid-19 in Sweden. Lack of experienced staff and medical skills, and for many temporary workers and unskilled hourly workers, has exacerbated the corona crisis in many of the country's 2,000 elderly homes.
A nurse who wants to be anonymous for fear of losing her job is upset when she contacts SvD. She works at a municipal residence where 14 elderly people have died and two have been hospitalized and died there during one of the corona months. Usually one to three people per month die on the property.
- It hurts the heart that so many have died. In the beginning, the management claimed that we had cleaned too badly. They didn't understand what was going on. We received no protective equipment or information about the spread of infection. We had to fix the mouthguards ourselves by washing cloths, she says.
Hand liquor and plastic clothing were not obvious at first and many of the staff became ill. But it was filled with new hourly employees who had never been to a retirement home before.
- Most people knew no Swedish and no one cared to explain to them, says the nurse and continues:
- Some were scared and did not want to go in to those who were infected. It was terrible for everyone, but mostly for the sick old. At night we are three nurses and a nurse who will keep track of six floors with a total of 54 elderly. This is not really possible, but now some rooms are empty, nobody wants to move here.
She also testifies that doctors are on site at most once a week.
There, she puts her finger on the most serious problem in the elderly, according to several of the experts SvD spoke to. Namely, the absence of doctors employed by the municipality both in the municipal management and in the individual residents.
- It is incomprehensible that geriatricians who are experts in the diseases of the elderly are not present in special elderly homes where our very sickest live. Something that has led to the death of the elderly has been unnecessarily dead, believes senior researcher Ingemar Skoog, director of the Center for Aging and Health at the University of Gothenburg.
He believes that it is time to change the so-called Ädelreformen from 1992. This meant that the municipalities were given a total responsibility for long-term service, care and care for the elderly. The focus was on the healthy in the elderly, and not on the sick. Therefore, the municipality would not have any doctors of its own. The person with the highest medical competence would be a "mas" - a medically responsible nurse.
- The elderly are usually listed at a health center and then there are general practitioners to call when needed. But there is no physician naturally in the organization, despite the fact that the elderly have become more ill at our elderly homes, says Ingemar Skoog, who now wants to get the geriatric expertise just like in Norway.
- Not only nursing, but also qualified healthcare is needed. And then medical knowledge and responsibility must be increased.
Ulf Nilsson, who lives in Ljungbyhed, has his 81-year-old mother at an Alzheimer's residence in Klippan municipality. He has pressed the municipality for tests to be carried out by the staff and that there should be requirements for oral protection.
- The strange thing is that it becomes a work environment issue where it is about protecting the staff from being infected by the old ones. It's not about protecting the old from being infected by the staff, says Ulf Nilsson.
He describes a development in which the elderly are exposed to constant savings. A new housing for Alzheimer's was closed for financial reasons and there is a shortage of specially trained nurses.
Olivia Wigzell, Director General of the National Board of Health, agrees that medical skills must be strengthened in municipal care.
- It must be in the municipal management. And the housing needs more experienced staff, both nurses and under-nurses. Whether to open up to the municipalities to have their own doctors is a political issue.
The Medical Association's Deputy Chairman Karin Båtelson believes that the pandemic has shown the need for a chief physician in each municipality, and that there is a medically responsible physician in the elderly care.
Through the Ädelreformen, the municipalities were given responsibility for social services and care, but also a healthcare assignment that corresponds to about 25 percent of the entire Swedish health care system.

- Traditionally, it has been regarded as a second-class health care activity. But then it has not been understood how great the healthcare needs are in the elderly. The most important thing for them is the continuity, a regular doctor's contact, says Anna Nergård, the government's special investigator for good and close care.

Former Social Democratic Minister Margareta Winberg is now investigating the social services of the future. She points out that the elderly residents came to be able to cook some food and cook coffee in their own little apartment. The social was more important than the medical.
- Nowadays, many are very ill. The time from when they get there and they die is very short and many describe it as a hospice, she says.

The chairman of the health care association Sineva Ribeiro also thinks that the skills must be increased in order to cope with multi-ill elderly people in special housing. But she would rather have more nurses than employed doctors in the municipalities.
- There are too few nurses and particularly advanced specialist nurses in the elderly. In Norway, there have not been so many deaths at their homes, and that is because every fifth employee in the elderly care is a nurse. This is three times more than in Sweden, Sineva Ribeiro points out.

In the Stockholm region, Familjeläkarna is one of the largest health care companies and is hired by 45 different elderly residents. Here, several hundred elderly patients have been found infected with covid-19 and many have died. For example, at the accommodation and care accommodation Berga in Solna, where at least 27 of the 96 inhabitants have died and almost half of the workforce has been or is on sick leave, according to the safety representative. A preliminary investigation is ongoing of several cases of work environment violations.
Stefan Amér, director of operations for Family Physicians, does not want to comment on a single accommodation that is under investigation. But he does not think that the corona eruption shows that there are no permanent doctors at the accommodation.
- It works well as long as the doctor becomes a bridge between municipal and regional health care, he says.
Andreas Fischer, chairman of the Hospital Doctors in Stockholm, on the other hand, believes that the form of employment is absolutely crucial. A private medical company is backed by its agreement.
- As a consultant, the doctor has no mandate to influence. In case of trouble, the doctor is replaced. If, on the other hand, we are part of the organization, the physician must ultimately guarantee patient safety. Not ignoring what a centrally placed general practitioner says doesn't look so good in a meeting protocol, says Andreas Fischer.
The Healthcare Region Council Anna Starbrink (L) believes that it does not matter where the doctors are employed. The important thing is that their skills are in the elderly care and that they are more often in place physically.
- But it is equally important to strengthen the competence of the nursing staff, for example we must have a proper degree for the nurses, she says.
Yngve Gustafson, senior professor of geriatrics, is not surprised by the high mortality rate in elderly housing. He has worked in the care of the elderly for 35 years and has a long research career with a focus on the elderly behind him.
- The Stockholm region has totally failed and has not offered many elderly people adequate care. If you give sedative like morphine and Midazolam then it is respiratory inhibitory. If you already have covid-19 with the risk of low oxygenation, you are practically doomed, says Yngve Gustafson.
But it is not only the medical skills that are lacking in the elderly housing. Yngve Gustafson says he is surprised that the Public Health Agency never mentions the nutritional status of the elderly.
- About a third of all elderly people suffer from nutritional deficiencies such as protein and iron. For those who are seriously ill, it may take a few months to recover, but for most people with moderate malnutrition, it can take a few days.
Older people have poorer uptake of protein but by splitting the meal on more occasions during the day, uptake can be increased.
An older person who gets a high fever is also quickly dehydrated, which requires quick action.
- Malnutrition and fluid deficiency are the strongest risk factor. Nutrition is extremely crucial to preventing and increasing the chance of recovery, says Yngve Gustafson.
To him, the realization of this is not new. Recently, the National Board of Health and Welfare explained that the mortality rate for special housing is not so much higher than in other years. But Yngve Gustafson thinks that mortality from vomiting sickness and seasonal flu even in an ordinary year is unacceptably high. The shortcomings that became clear during the corona crisis have long existed.
- In the case of vomiting, 90 percent would survive if they were allowed to drip for one to three days, he claims.
- The Stockholm region should be sued. I stand for that. In some homes, the risk of dying in covid-19 has been increased 50 times. In many places, night and weekend staffing is extremely low. Staff have had to run between departments and have not been able to change protective equipment. Assessments have been made by phone. It's such an outrageously poor quality, ”says Yngve Gustafson.

The figures indicate, in absolute terms, the number of cases of care for patients in the 70-79 age group and, where applicable, the number of patients 80-89 years and 90 years and older, respectively.
This is followed by the total number of cases at all ages during the week and thereafter the proportion that patients older than 70 years make up the total number of patients at all ages during the week.
The number of care places has been expanded during the period and was a maximum of 1060.
The text states that the proportion of older covid-19 patients in intensive care decreased as the pressure increased. By the increased pressure is meant the daily reported statistics from the Public Health Authority and the National Board of Health, which shows that the number who tested positive during these weeks has gone from close to zero to now over 37,000 and that 90 percent of the deceased have been older than 70 years.
 
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I knew there was one last point I wanted to bring up. I find it ironic that in the same states where people have been threatened with citations, fines, or even misdemeanor charges (i.e. a criminal record) for being out of the house unnecessarily while COVID-19 is an ongoing concern are being allowed to violate those same restrictions with impunity when they're out protesting or causing mayhem the past few days.

I also agree with whomever posted here or in the riot thread that we'll learn a lot more about COVID-19 in the next two weeks. If cases don't spike from protestors going out without masks and social distancing, it's going to be very difficult to sell independent-minded people on the claims that a second wave is inevitable the instant people start doing too many things out in public without precautions.

Also, I agree with the article that @JosephStalin posted that people largely confined to home for nearly three months with no outlet for their pent-up energies probably hit the boiling point this weekend. I believe most people are eager to partake in any sort of activity as soon as they're allowed to do so. Unfortunately, this isn't exactly the kind of activity anyone anticipated or probably wanted to see take place.
Vox Populi, Vox Dei
 
I've gathered some more intel and I think I've found out why COVID-19 disproportionately kills black people. It has to do with differences in endothelial function. Black people have substantially higher rates of high blood pressure and diabetes. It has to do with diet, genetics, and skin pigmentation. If someone is vitamin D deficient (that is, if they have less sun exposure because they're sedentary and always have a roof over their heads; black people carry the roof with them, it's called melanin), they'll have more NADPH oxidase activity and more oxidative stress. Vitamin D restrains and regulates the production of reactive oxygen species.


One such example of ROS is superoxide, produced by the action of NADPH oxidase. Superoxide reacts with nitric oxide to form peroxynitrite, a powerful oxidizing and nitrating agent that's cytotoxic. In the process, nitric oxide is depleted. Black people naturally produce more superoxide and peroxynitrite (i.e. they're always in a redox state).


To make matters worse, COVID-19 alters one's lipid and metabolite profile, reducing carbamoyl phosphate levels.


Normally, carbamoyl phosphate reacts with ornithine to form citrulline, and then it is converted to arginine, and finally, it's converted to nitric oxide.

Nitric oxide is a vasodilator and it's critical to endothelial health. If it's being converted into peroxynitrite by excess superoxide, and if carbamoyl phosphate is cut off, then nitric oxide is inevitably depleted. And this is what we're seeing in COVID-19. Loss of NO bioavailability.



This is concerning, because nitric oxide does more than support endothelial health. It also has a possible direct antiviral effect against coronaviruses. We know it can block the Spike protein and slow the replication of SARS-CoV. Due to their similarities, it may also be able to slow the replication of SARS-CoV-2.


In summary, black people are already teetering towards endothelial dysfunction just by default, all the time. COVID-19 tips the balance even further, with lethal consequences. This is most likely why COVID-19 disproportionately kills blacks.

I think the key to saving African-American patients sick with COVID-19 (as well as many of the other more severe cases) is to restore NO bioavailability. Nicotine and Vitamin D can regulate or even inhibit excessive NADPH oxidase activity. Citrulline, arginine, and cysteine supplementation can significantly increase nitric oxide.

To recap, SARS-CoV-2 can:
  • Get into the brain and cause encephalitis and new-onset seizure, with detectable virions in the cerebrospinal fluid.
  • Cause temporary loss of sense of smell and/or taste.
  • Infect the lungs and cause bilateral viral pneumonia, pulmonary fibrosis, and even full atelectasis of both lungs.
  • Cause hypoxemic insult to all of the vital organs.
  • Infect the lining of blood vessels and cause endotheliitis and even a Kawasaki disease-like syndrome in children.
  • Cause coagulopathy, viremia, and sepsis, with clotting severe enough to cause heart attacks, strokes, or even PE. Patients have thrombocytopenia because their platelets are used up, and their D-dimer levels are often well above 3000 ng/ml, and sometimes as high as 20,000+ ng/ml.
  • Infect the heart muscle and cause heart injury. Noticeable in elevated troponin levels.
  • Infect the liver and/or bile duct, causing abnormal liver enzyme levels.
  • Infect the kidneys and cause acute kidney injury requiring dialysis.
  • Infect the GI tract and cause abdominal pain and diarrhea.
  • Infect the testes and cause testicular pain, hormone imbalance, and possible male sterility.
  • Destroy T lymphocytes and cause lymphopenia.
  • Inhibit interferon production.
  • Imbalance the renin-angiotensin-aldosterone system and cause hypokalemia, oxidative stress, and severe inflammation, injuring tissues with cytokine storms and destabilizing atherosclerotic plaques.
  • Alter one's lipid and metabolic profile (in the case of SARS, this could even become permanent).
COVID-19 can look like (and be misdiagnosed as) any of the following things:
  • Pneumonia
  • Seizure
  • Stroke
  • Heart attack
  • Pulmonary embolism
  • Idiopathic pulmonary fibrosis
  • Kidney failure
  • Autoimmune disease
Any treatment must necessarily take all of this into account.
  • Vasodilation and bronchodilation for the lungs, as well as a nasal cannula supplying oxygen or intubation and mechanical ventilation. Nitric oxide inhalation may be very helpful.
  • Vitamin D, nicotine, citrulline, arginine, and/or cysteine to try and increase NO levels.
  • Anti-seizure medication, if necessary, like levetiracetam.
  • Anticoagulation therapy. Lots of heparin.
  • IV immunoglobulin for endotheliitis/capillary leak.
  • Dialysis, if the kidneys are having a hard time.
  • Lopinavir/ritonavir, camostat, and/or interferon to cut down on viral replication.
  • Monoclonal antibodies against each specific inflammatory cytokine, like tocilizumab.
I've had to listen to a bunch of politically-correct morons say "Oh, it's structural disadvantage, not genetics", trying to imply that it's nothing intrinsic in black people making them more susceptible to COVID-19. Wrong. It's both. If someone has a diet high in fats and carbohydrates and low in micronutrients, like the typical lower-class American diet of cheap processed crap, COVID-19 will kill them dead. This is especially true of people who have a harder time synthesizing their own nutrients, like people with dark skin living at higher latitudes who are vitamin D deficient and already had endothelial dysfunction before they were infected with a virus that causes severe endotheliitis. Vox tried to imply that it was living next to chemical plants that made black people more susceptible to COVID-19. What these geniuses cannot explain is why the disparity holds basically everywhere, not just right next to industrial zones.


Medicine doesn't give a damn about political correctness. People need therapy that's tailored to their genetics. Deluding ourselves into thinking that we're all physically identical is going to hurt and kill innocent people.
TLDR; Blacks should be sent back back to the Wakanda, as God intended (also get refund from the G-d's chosen people, who were the only ones selling and shipping them), where they won't have D-Vitamin deficiency.
 
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What happens if Ebola-san and Corona-chan gets married and have a child?

unlikely. Both are SSRNA viruses but one is positive sense and one negative sense. I do t think they can swap material.

Rate me late but isn't Covid losing traction in Italy and becoming less lethal?
Somewhat related, these protests and riots will be a real test if things really are getting better because that's a super spreader. If by two weeks no one gets sick from this, we should be in the clear to go back to somewhat normalcy.

yeah I read that - they’re saying they are getting much lower viral loads now. I’m not sure they can say that means it’s mutated to be less virulent but it’s a clinical observation that is interesting and needs to be looked at.

My own read on situation is that it is not becoming less lethal, but people, who were going to die to it have mostly died.

yes I think I’d agree. It’s scythed off those who were vulnerable. That also implies that:
1. A lot of people already had some kind of immunity.
2. If it was consistently spreading good see further outbreaks across less populated areas. While that’s happening a bit, it’s not happening enough to really drive the high level of infection. That seems to mean that basic distancing, of the sort that people who don’t live in densely populated areas do anyway, may be enough. This is a city disease.

It has to do with differences in endothelial function. Black people have substantially higher rates of high blood pressure and diabetes. It has to do with diet, genetics, and skin pigmentation
People of black African origin have genetic differences in the renin/angiotensin system. That leads to specific types of hypertension and differences in blood pressure from birth.
 
Well, well, well...have to ask if any of these governmental units really asked WHY tax revenues have gone down. Nah, takes too much thinking and common sense. When governors put entire states under house arrest for interminable periods, guess what? Income tax revenues go down! Sales tax revenues go down! Gasoline tax revenues go down! Hotel/motel occupancy taxes go down! Likely other taxes go down! But that obviously didn't register in the mind of ANY of these little Hitlers. If it had, we'd have seen the two-week lockdown, then quarantine hotspots and buffer zones, let others go back to work/school. Tax revenues would drop some, but not catastrophically. Fuck, no! Every one of these little Hitlers creamed their jeans/panties as a chance to enjoy a power play. Most of them are still fucking with their people. NFG for these states.

As an aside, believe some deadwood can be trimmed in every jurisdiction.


 
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Michigan, USA

Governor Gretchen Whitmer (D) is keeping the hair salons and barbershops closed longer than nearly all other establishments, and has told people to "Google how to do a haircut." Barbers and hair stylists are not happy.
(archive)

MICHIGAN RECAP
Most stuff reopened or about to be. Death toll and new cases way down. It's looking like it's all over except the lawsuits.

OFFICIAL DEATH TOLL

The Michigan Department of Health and Human Services reviews deaths and adds overlooked cases to the count three days a week: Tuesday, Thursday, and Saturday (usually). Recovery counts are updated on Saturdays.
11 deaths were added yesterday.

MDHHS said:
Regular reviews of death certificate data maintained in Vital Records reporting systems are conducted by MDHHS staff three times per week. As a part of this process, records that identify COVID-19 infection as a contributing factor to death are compared against all laboratory confirmed cases of COVID-19 in the Michigan Disease Surveillance System (MDSS). If a death certificate is matched to a confirmed COVID-19 case and that record in the MDSS does not indicate the individual died, the MDSS record is updated to indicate the death and the appropriate local health department is notified. These matched deaths are then included with mortality information posted to the Michigan Coronavirus website.

Detroit Metro (pop. 3,860,000 total; 1,796/sq. mi.; 694/sq km):*

35,735 confirmed / 4,308 dead
35,600 confirmed / 4,292 dead yesterday
(i.e. 16 new deaths, down 30 from this day last week)
Normal Detroit Metro Death Rate: 104 per day.**

Other Michigan (6,120,000; 65/sq. mi.; 25/sq km):

22,300 confirmed / 1,262 dead
22,131 confirmed / 1,261 dead yesterday
(i.e. 1 new death, down 21 from this day last week)
Normal not-Detroit Death Rate: 167 per day**

All Michigan (9,990,000; 103/sq. mi.; 40/sq km):

58,035 confirmed / 5,570 dead
57,731 confirmed / 5,553 dead yesterday
(i.e. 17 new deaths, down 51 from this day last week, down 37 with no adjustments)
Normal Michigan Death Rate: 271 per day.**

Death toll doubled since: April 21.
We were locked down from: March 24 (until April 30? May 21 June 1),
Masks have been mandatory in stores since: April 27 (until April 30?).

Detroit Metro Daily Deaths Last Seven Days:
17*** / 25 / 19*** / 23 / 10 / 13*** / 16 = 157***

State Government site, daily - today's archive;
State Gov site, total, includes breakdowns by sex, age, race and ethnicity - today's archive.
*Here defined as the City of Detroit, and Macomb, Oakland, and Wayne Counties, minus state and federal prisoners, who are not counted towards any county's cases, but are kept in categories of their own.
** As of 2018.
*** 17, 37, and 11 statewide deaths, respectively, were added on these days upon State review. I don't know how many were in Detroit.

One Ann Arbor man allegedly killed by his roommate in a Corona-related dispute (archive). The suspect has been released from custody while the investigation continues (archive).
One Flint security guard allegedly murdered for telling a woman that her daughter needed to wear a mask in a dollar store. Multiple suspects are in custody (archive, A&N thread).
 
I also agree with whomever posted here or in the riot thread that we'll learn a lot more about COVID-19 in the next two weeks. If cases don't spike from protestors going out without masks and social distancing, it's going to be very difficult to sell independent-minded people on the claims that a second wave is inevitable the instant people start doing too many things out in public without precautions.

I honestly can't remember if it was linked in the riot thread or something I came across myself elsewhere, But I did see an article about that - Apparently if/when wuflu cases spike in a couple weeks, it's not the protesters but those meanie cops using teargas causing spread. Which I wouldn't be at all surprised if that stuff does make things worse.

But whoever wrote the thing either didn't think that it pretty much means large, tight-packed gatherings themselves aren't themselves much of a problem or doesn't think anyone else will. Well, Are they or aren't they?

ETA: Here it is. Not quite as clear as I remembered. Just a bunch of speculation.
https://www.nytimes.com/2020/06/03/us/tear-gas-risks-protests-coronavirus.html
Archive (Someone else got it first) https://t.co/y6Z6hhiF1X?amp=1
 
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Not sure if this was already brought up:


Governments and WHO changed Covid-19 policy based on suspect data from tiny US company

"Science based decision making." God damn it. I had to fucking hear people regurgitate media talking points with absolutely no fucking skepticism because fucking people can't figure out the media is there to scare the shit out of you.
 
Not that it's really news to anyone here, but in a nutshell the CDC fucked up since the very beginning. A couple paragraphs of Trump stuff but the article was originally in the NYT, so that's a given. The link to the original NYT article is broken for some reason so Yahoo it is.

A few months ago we were told to "listen and believe" these assholes because they were "experts." That was kind of hard to do anyway since their statements and suggestions were often directly contradictory to each other, and continue to be.


 
I'm hearing that the local school district will be offering classes both online and in person this fall. Enrollment is down to the point where they're combining some lower grades into one class. Some teachers have been let go too.

Funny, I thought this was over and we'd moved on to protests.
 
Stumbled upon this piece of info in Financial Times updates...apparently WuFlu was not a contributing factor.

gfcorona.jpg
 
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