Sickle trait only acts like sickle cell during extreme hypoxia, but it capable of further complicating such events. In other words, if you are severely oxygen deprived in a certain area due to restricted blood flow, the red cells will sickle up and start clots. If you are systemically deprived of oxygen enough to trigger sickle trait, then you're already dead so it doesn't matter anymore. So, if blood flow gets cut off, clots form, causing more loss of blood flow, causing more clots.
In looking for something like that after reading your comment, I recalled a website called SBPDL - Stuff Black People Don't Like. Seems defunct now, but hey look - you can buy the book!
There's a joke in there somewhere, I'm sure of it.
In looking for something like that after reading your comment, I recalled a website called SBPDL - Stuff Black People Don't Like. Seems defunct now, but hey look - you can buy the book!
Sickle trait only acts like sickle cell during extreme hypoxia, but it capable of further complicating such events. In other words, if you are severely oxygen deprived in a certain area due to restricted blood flow, the red cells will sickle up and start clots. If you are systemically deprived of oxygen enough to trigger sickle trait, then you're already dead so it doesn't matter anymore. So, if blood flow gets cut off, clots form, causing more loss of blood flow, causing more clots.
I guess I ought to clarify. So, typical sickle cell disease turns your regular donut-shaped red blood cells into banana-shaped red blood cells when your blood hits ~80 oxygen saturation levels. You can survive at those levels, where as sickle trait only sees the cells go bananas around 50% oxygen saturation, which is deadly low. Anything below 65% is associated with cyanosis, aka when you start going blue, aka how a junkie's lips look when they're overdosing. You can survive localized cyanosis though, like if blood flow gets cut off to your hand, it might go cyanotic enough to cause sickling in that area.
In Floyd's case, he was on enough fentanyl that he would have needed a respirator to work his lungs for him (anesthetic dose) and his methed up lung tissues were likely damaged and filled with water instead of blood according to the autopsy. So, you would see systemic hypoxia and it wouldn't take much blood flow restriction for individual areas to become cyanotic. For example, a heart vein with 90% occlusion is barely providing oxygen during the best of times. Now add meth and fentanyl and you see that area starving of oxygen, blood cells in those arteries sickling up and further blocking blood flow, and it's a massive cardiac event.
I guess I ought to clarify. So, typical sickle cell disease turns your regular donut-shaped red blood cells into banana-shaped red blood cells when your blood hits ~80 oxygen saturation levels. You can survive at those levels, where as sickle trait only sees the cells go bananas around 50% oxygen saturation, which is deadly low. Anything below 65% is associated with cyanosis, aka when you start going blue, aka how a junkie's lips look when they're overdosing. You can survive localized cyanosis though, like if blood flow gets cut off to your hand, it might go cyanotic enough to cause sickling in that area.
In Floyd's case, he was on enough fentanyl that he would have needed a respirator to work his lungs for him (anesthetic dose) and his methed up lung tissues were likely damaged and filled with water instead of blood according to the autopsy. So, you would see systemic hypoxia and it wouldn't take much blood flow restriction for individual areas to become cyanotic. For example, a heart vein with 90% occlusion is barely providing oxygen during the best of times. Now add meth and fentanyl and you see that area starving of oxygen, blood cells in those arteries sickling up and further blocking blood flow, and it's a massive cardiac event.
I mean it can't just be at extreme hypoxia levels since it's the main cause of death in African Americans in military basic training. While it is obviously a lot of exertion I doubt they're training to the point of cyanosis in basic.
I mean this guy was obviously in poor physical condition and stuffed full of a cocktail of drugs at OD level but if its felling recruits in basic it's obviously not just for the blocked artery druggies of the world.
Edit found some stuff. Yeah there is a few options and probably a few coincided here
In looking for something like that after reading your comment, I recalled a website called SBPDL - Stuff Black People Don't Like. Seems defunct now, but hey look - you can buy the book!
The sad reality of the entire ACAB, BLM, social justice shit about cops is if you actually read the police reports or watch the videos you will almost always see them reach for a gun, reach for a cops gun, refuse commands from an officer then lunge at them. Cops don't shoot people for fun. It's a massive amount of paperwork, legal trouble, makes your department look bad and can cost you your job and jail time possibly. Every round a cop fires has to be accounted for. You have to show it was a reasonable use of force. This is true even in shitty state prisons, let alone in social justice run hellholes like Baltimore, Chicago, Detroit, Minne
A little more on Lt. Richard Zimmerman of MNPD. Nothing outrageous.
There's a dismissed appeal that names him as the respondent in allegations of excessive force, but reading the actual notes it appears to refer to an Officer Scheu [archive]. There may be a legitimate reason for this, but I don't know it.
He has an IMDB page as Rick Zimmerman, having appeared as himself in multiple episodes of The First 48 between 2008-18, as well as consulting. The A&E page is gone, but I found a cached version with a photograph confirming it's him [archive].
An article from CBS MN January 2020 quotes him upon the death of a black community activist:
"It helped change the culture of the department. It helped the white officers as much as it helped the young black officers that wanted to become police officers".
To be clear, I don't think this means much in terms of racial bias, more that he is a bit of a starfucker and angling for fame. Whoever it was that predicted a run for office, that sounds about right.
Edit: more from the A&E page here c/o @Fursei. Thank you! I forgot to include caps.
It has vicious premeditated murder, sexual manipulation, Mormonism, a Karen defence atty, an aggressive prosecutor, and the murderer took the stand in her own defense for over three weeks. First clip is 15min, the rest are very brief.
Trial compilation (NSFW, the first atty is defense):
An 'expert' witness (the jury get to ask questions to each witness in AZ):
on the subject ofBlack Women bringing religion into courts: that story was included with several others in Face to Face With Race, a collection of American Renessiance articles. I love this collection of names one lawyer collected.
In looking for something like that after reading your comment, I recalled a website called SBPDL - Stuff Black People Don't Like. Seems defunct now, but hey look - you can buy the book!
Pshaw, you thought I was gonna say you had to travel all the way to Liberia to immerse yourself in pure kang-culture. Kinda makes you think about Michelle Obama's decrying of white people 'fleeing'.
I'm not gonna powerlevel, but I'll note that in some remote places I've lived, it's an amazing thing how folks somehow manage to solve problems with their own ingenuity, rather than waiting for the government to come in and get 'er done. Also, Romans had functioning sewers over two thousand years ago. Romans! They were fucking Italians ("The other nigger") to boot!
In looking for something like that after reading your comment, I recalled a website called SBPDL - Stuff Black People Don't Like. Seems defunct now, but hey look - you can buy the book!
Sickle trait only acts like sickle cell during extreme hypoxia, but it capable of further complicating such events. In other words, if you are severely oxygen deprived in a certain area due to restricted blood flow, the red cells will sickle up and start clots. If you are systemically deprived of oxygen enough to trigger sickle trait, then you're already dead so it doesn't matter anymore. So, if blood flow gets cut off, clots form, causing more loss of blood flow, causing more clots.
It can happen to pro athletes too, Ryan Clarke was a steelers player with sickle cell trait who almost died on his first trip to play the broncos in Denver. The lower O2 levels at altitude caused his blood cells to start collapsing and going sickle shaped which caused an infarction in his pancrease.
I mean it can't just be at extreme hypoxia levels since it's the main cause of death in African Americans in military basic training. While it is obviously a lot of exertion I doubt they're training to the point of cyanosis in basic.
I mean this guy was obviously in poor physical condition and stuffed full of a cocktail of drugs at OD level but if its felling recruits in basic it's obviously not just for the blocked artery druggies of the world.
Edit found some stuff. Yeah there is a few options and probably a few coincided here
Hypoxygenation is something that actually can happen quite easily even in relatively fit people. It's all about conditioning, and not just pure aerobics. And Once sickle cell kicks in I'm assuming it gets exponentially worse.
For example when I was a kid I was fairly chunky, but ran a lot and hiked a lot. I was able to hike for literally hours, carrying heavy weight, without stopping. I could jog for like, hours with no problem too.
But put me on a mountain bike and I would fucking pass out. Just something about those big ass leg muscles going 100% for a minute or two would put me at an oxygen deficit, and I would wheeze like an asthmatic. I wouldn't even be tired at first, it would just feel like my throat was closing up and I would huff air like I was addicted to it.
When I started working out, it was the same thing. I would finish easy work outs choking and then go for a run 15 minutes later just fine. Within 2 weeks of working out that stopped.
People tend to work out at their comfort level, and when you push them outside it they crash and burn. I can imagine some kid whose ripped having to run cardio, and suddenly those big burly muscles become a problem. They don't breath right. They hit 49% in their legs. Banana blood. Death.