There are, but I haven't tried any of them myself save for
BlockTube, which I'd recommend in the strongest possible terms.
I'll give you a little demonstration from a fresh install.
View attachment 6147717
This is Mr. Beast. I do not like Mr. Beast.
In an ideal world, I would like to see him screaming in agony, ribcage splayed open, crucified on a burning upside-down cross in my backyard.
This is not an ideal world though, so never having his videos shilled to me again will have to suffice.
View attachment 6147729
All I have to do to make my dreams a reality is to hit the three dots on the right, hit "Block Channel"...
View attachment 6147734
...and voila.
View attachment 6147754
Never again will his airbrushed faggot face disgrace my sidebar.